Calcium information, including Technical Data, Safety Data and its High Purity properties, research, applications and other useful facts are discussed below. Scientific facts such as the atomic structure, ionization energy, abundance on Earth, conductivity and thermal properties are included.
 Calcium is a member of the alkaline earth elements. Calcium is an essential metal for living organisms and is non-toxic. Its primary commercial application is in its metallic form as a reducing agent in the production of other metals. In iron and steel production it is added to the melt to remove oxygen, sulfur and carbon. The various calcium compounds have wide application in food, pharmaceutical and cosmetics. It is used in small doses in alloys of copper and beryllium. It is used in dietary supplements and food production because it has been shown to improve bone and dental health.
Calcium facts, including appearance, CAS #, and molecular formula and safety data, research and properties are
available for many specific states, forms and shapes on the product pages listed to the left. Elemental or metallic forms include pellets, rod, wire and granules for evaporation source material purposes. Nanoparticles and nanopowders provide ultra high surface area which nanotechnology research and recent experiments demonstrate function to create new and unique properties and benefits.
Oxides are available in forms including powders and dense pellets for such uses as optical coating and thin film  applications. Oxides tend to be insoluble. Fluorides are another insoluble form for uses in which oxygen is undesirable such as metallurgy, chemical and physical vapor deposition and in some optical coatings. Calcium is available in soluble forms including chlorides, nitrates and acetates. These compounds are also manufactured as solutions at specified stoichiometries.
Calcium is a Block S, Group 2, Period 4 element. The number of electrons in each of Calcium's shells is 2, 8, 8, 2 and its electronic configuration is [Ar] 4s2. In its elemental form calcium's CAS number is 7440-70-2. The calcium atom has a radius of 197.4.pm and it's Van der Waals radius is 200.pm.
 All elemental metals, compounds and solutions may be synthesized in ultra high purity (e.g. 99.999%) for laboratory standards, advanced electronic, thin fillm deposition using sputtering targets and evaporation materials, metallurgy and optical materials and other high technology applications. Information is provided for stable (non-radioactive) isotopes. Organo-Metallic Calcium compounds are soluble in organic or non-aqueous solvents. See Analytical Services for information on available certified chemical and physical analysis techniques including MS-ICP, X-Ray Diffraction, PSD and Surface Area (BET) analysis.
Calcium was first discovered by Sir Humphrey Davy in 1808. The name calcium originates from the Latin word 'calics' meaning lime.
 calcium |
 Calcium |
 calcio |
 Cálcio |
 calcio |
 Kalcium
|
Abundance. The following table shows the abundance of calcium and each of its naturally occurring isotopes on Earth along with the atomic mass for each isotope.
| Isotope |
Atomic Mass |
% Abundance on Earth |
| Ca-40 |
39.9625911 |
96.94 |
| Ca-42 |
41.9586183 |
0.65 |
| Ca-43 |
42.9587668 |
0.14 |
| Ca-44 |
43.9554811 |
2.09 |
| Ca-46 |
45.953693 |
0.01 |
| Ca-48 |
47.952534 |
0.19 |
The following table shows the abundance of Calcium present in the human body and in the universe scaled to parts per billion (ppb) by weight and by atom:
| |
Typical Human Body |
Universe |
| by Weight |
14000000 ppb |
70000 ppb |
| by Atom |
2200000 ppb |
2000 ppb |
Safety Data and Biological Role. The safety data for calcium metal, nanoparticles and its compounds can vary widely depending on the form. For potential hazard information, toxicity, and road, sea and air transportation limitations, such as DOT Hazard Class, DOT Number, EU Number, NFPA Health rating and RTECS Class, please see the specific material or compound referenced in the left margin. Calcium compounds have an essential biological role for all life. Calcium helps form cell walls and bones, and is an important component in the coagulation of blood.
Ionization Energy. The ionization energy for calcium (the least required energy to release a single electron from the atom in it's ground state in the gas phase) is stated in the following table:
| 1st Ionization Energy |
589.83 kJ mol-1 |
| 2nd Ionization Energy |
1145.46 kJ mol-1 |
| 3rd Ionization Energy |
4912.40 kJ mol-1 |
Conductivity. As to calcium's electrical and thermal conductivity, the electrical conductivity measured as to electrical resistivity @ 20 ºC is 3.91 μΩcm and its electronegativities (or its ability to draw electrons relative to other elements) is 1. The thermal conductivity of calcium is 190 W m-1 K-1.
Thermal Properties. The melting point and boiling point for calcium are stated below. The following chart sets forth the heat of fusion, heat of vaporization and heat of atomization.
| Heat of Fusion |
9.33 kJ mol-1 |
| Heat of Vaporization |
150.6 kJ mol-1 |
| Heat of Atomization |
177.74 kJ mol-1 |
Recent Research & Development for Calcium
Prevention of preterm labour: 2011 update on tocolysis.
Hubinont C, Debieve F.
J Pregnancy. 2011;2011:941057. Epub 2011 Nov 15.
PMID:
22175022
[PubMed - in process]
Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector.
Addis RC, Hsu FC, Wright RL, Dichter MA, Coulter DA, Gearhart JD.
PLoS One. 2011;6(12):e28719. Epub 2011 Dec 9.
PMID:
22174877
[PubMed - in process]
Dysferlin Interacts with Histone Deacetylase 6 and Increases alpha-Tubulin Acetylation.
Di Fulvio S, Azakir BA, Therrien C, Sinnreich M.
PLoS One. 2011;6(12):e28563. Epub 2011 Dec 8.
PMID:
22174839
[PubMed - in process]
Regulation of Brain-Derived Neurotrophic Factor Exon IV Transcription through Calcium Responsive Elements in Cortical Neurons.
Zheng F, Zhou X, Luo Y, Xiao H, Wayman G, Wang H.
PLoS One. 2011;6(12):e28441. Epub 2011 Dec 9.
PMID:
22174809
[PubMed - in process]
Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for angelman syndrome.
Daily JL, Nash K, Jinwal U, Golde T, Rogers J, Peters MM, Burdine RD, Dickey C, Banko JL, Weeber EJ.
PLoS One. 2011;6(12):e27221. Epub 2011 Dec 9.
PMID:
22174738
[PubMed - in process]
Nifedipine Protects INS-1 ß-Cell from High Glucose-Induced ER Stress and Apoptosis.
Wang Y, Gao L, Li Y, Chen H, Sun Z.
Int J Mol Sci. 2011;12(11):7569-80. Epub 2011 Nov 7.
PMID:
22174617
[PubMed - in process]
Chitosan Fibers Modified with HAp/ß-TCP Nanoparticles.
Wawro D, Pighinelli L.
Int J Mol Sci. 2011;12(11):7286-300. Epub 2011 Oct 25.
PMID:
22174598
[PubMed - in process]
Mild and moderate pre-dialysis chronic kidney disease is associated with increased coronary artery calcium.
Roy SK, Cespedes A, Li D, Choi TY, Budoff MJ.
Vasc Health Risk Manag. 2011;7:719-24. Epub 2011 Dec 2.
PMID:
22174582
[PubMed - in process]
Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZ.
Duprez D, Ferdinand K, Purkayastha D, Samuel R, Wright R.
Vasc Health Risk Manag. 2011;7:701-8. Epub 2011 Nov 24.
PMID:
22174580
[PubMed - in process]
Leukotriene E4 Activates Human Th2 Cells for Exaggerated Proinflammatory Cytokine Production in Response to Prostaglandin D2.
Xue L, Barrow A, Fleming VM, Hunter MG, Ogg G, Klenerman P, Pettipher R.
J Immunol. 2011 Dec 14. [Epub ahead of print]
PMID:
22174450
[PubMed - as supplied by publisher]
Association Between Depression and Vascular Disease in Systemic Lupus Erythematosus.
Greco CM, Li T, Sattar A, Kao AH, Danchenko N, Edmundowicz D, Sutton-Tyrrell K, Tracy RP, Kuller LH, Manzi S.
J Rheumatol. 2011 Dec 15. [Epub ahead of print]
PMID:
22174200
[PubMed - as supplied by publisher]
A rare electrocardiographic manifestation of a rare form of multiple electrolyte disturbances: hyperparathyroid crisis.
Hajsadeghi S, Chitsazan M, Miresmail SJ.
Acta Med Iran. 2011 Dec;49(12):824-7.
PMID:
22174173
[PubMed - in process]
A cross-sectional study to determine the prevalence of calcium metabolic disorder in malignant childhood cancers in patients admitted to the pediatric ward of vali-asr hospital.
Moayeri H, Oloomi Z, Sambo SA.
Acta Med Iran. 2011 Dec;49(12):818-23.
PMID:
22174172
[PubMed - in process]
Study to Evaluate Two Dosage Regimens of Vitamin D through an Academic Year in Middle School Girls: a Randomized Trial.
Shakiba M, Ghadir M, Nafei Z, Akhavan Karbasi S, Lotfi MH, Shajari A.
Acta Med Iran. 2011 Dec;49(12):780-3.
PMID:
22174164
[PubMed - in process]
Oxidative stress due to aluminium exposure induces eryptosis which is prevented by erythropoietin.
Vota DM, Crisp RL, Nesse AB, Vittori DC.
J Cell Biochem. 2011 Dec 15. doi: 10.1002/jcb.24026. [Epub ahead of print]
PMID:
22174104
[PubMed - as supplied by publisher]
Parameters Affecting the Efficient Delivery of Mesoporous Silica Nanoparticle Materials and Gold Nanorods into Plant Tissues by the Biolistic Method.
Martin-Ortigosa S, Valenstein JS, Sun W, Moeller L, Fang N, Trewyn BG, Lin VS, Wang K.
Small. 2011 Dec 16. doi: 10.1002/smll.201101294. [Epub ahead of print]
PMID:
22174078
[PubMed - as supplied by publisher]
Cell Excitability Necessary for Male Mating Behavior in Caenorhabditis elegans is Coordinated by Interactions Between BK and EAG Family K+ Channels.
Leboeuf B, Garcia LR.
Genetics. 2011 Dec 14. [Epub ahead of print]
PMID:
22174070
[PubMed - as supplied by publisher]
Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia.
Jung CB, Moretti A, Schnitzler MM, Iop L, Storch U, Bellin M, Dorn T, Ruppenthal S, Pfeiffer S, Goedel A, Dirschinger RJ, Seyfarth M, Lam JT, Sinnecker D, Gudermann T, Lipp P, Laugwitz KL.
EMBO Mol Med. 2011 Dec 15. doi: 10.1002/emmm.201100194. [Epub ahead of print]
PMID:
22174035
[PubMed - as supplied by publisher]
Vitamin D Regulates Anti-Mullerian Hormone Expression in Granulosa Cells of the Hen.
Wojtusik J, Johnson PA.
Biol Reprod. 2011 Dec 14. [Epub ahead of print]
PMID:
22174023
[PubMed - as supplied by publisher]
Mechanistic involvement of the calpain-calpastatin system in Alzheimer neuropathology.
Higuchi M, Iwata N, Matsuba Y, Takano J, Suemoto T, Maeda J, Ji B, Ono M, Staufenbiel M, Suhara T, Saido TC.
FASEB J. 2011 Dec 15. [Epub ahead of print]
PMID:
22173972
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