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Gadolinium Acetate
Gd(O2C2H3)3.4H2O
Product
Product Code
Order or Specifications
99% Gadolinium Acetate
GD-AC-01
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99.9% Gadolinium Acetate
GD-AC-03
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99.99% Gadolinium Acetate
GD-AC-04
 Contact American Elements
99.999% Gadolinium Acetate
GD-AC-05
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Gadolinium Acetate is a moderately water soluble crystalline Gadolinium source that decomposes to Gadolinium oxide on heating. It is generally immediately available in most volumes. Acetates are excellent precursors for production of ultra high purity compounds and certain catalyst and nanoscale(nanoparticles and nanopowders) materials. All metallic acetates are inorganic salts of a metal cation and the acetate anion. The acetate anion is a univalent (-1 charge) polyatomic ion composed of two carbon atoms ionically bound to three hydrogen and two oxygen atoms (Symbol: CH3COO) for a total formula weight of 59.05. Ultra high purity and high purity compositions improve both optical quality and usefulness as scientific standards. Nanoscale (See also Nanotechnology Information and Quantum Dots) elemental powders and suspensions, as alternative high surface area forms, may be considered. Gadolinium is utilized for both its high magnetic moment (7.94 µB) and in phosphors and scintillators. When complexed with EDTA ligands, it is used as an injectable contrast agent for patients undergoing magnetic resonance imaging. We also produce Gadolinium Acetate Solution. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement.

Gadolinium is a Block F, Group 3, Period 6 element. The electronic configuration is [Xe]4f75d16s2. In its elemental form gadolinium's CAS number is 7440-54-2. The gadolinium atom has a radius of 178.7.pm and it's Van der Waals radius is unknown. Gadolinium is utilized for both its high magnetic moment (7.94µB) and in phosphors and scintillator material. When complexed with EDTA ligands, it is used as an injectable contrast agent for patients undergoing magnetic resonance imaging. Gadolinium is available as metal and compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity); metals in the form of foil, sputtering target, and rod, and compounds as submicron and nanopowder.

Formula CAS No. Appearance Molecular Weight Solubility Stability
Gd(O2C2H3)3.4H2O 100587-93-7 White 334.39 Soluble in water, moderately soluble in strong mineral acids Slightly hygroscopic
PRODUCT CATALOG Gadolinium Research, Properties, & Information Submicron & Nanopowder Tolling Ultra High Purity Sputtering Target Crystal Growth Rod, Plate, Powder, etc. MSDS
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Recent Research & Development for Gadolinium

  • Gadolinium chloride suppresses styrene-induced cytochrome P450s expression in rat liver. Biomed Res. 2008 Dec;28(6):323-30.

  • Gadolinium and nephrogenic systemic fibrosis: association or causation. Nephrology (Carlton). 2008 Jun;13(3):235-41. Epub 2008 Jan 23.

  • Magnetic resonance imaging-based detection of glial brain tumors in mice after antiangiogenic treatment. Int J Cancer. 2008 May 1;122(9):1981-6.

  • Nephrogenic systemic fibrosis: chronic imaging findings and review of the medical literature. Skeletal Radiol. 2008 May;37(5):457-64. Epub 2008 Mar 7.

  • Gadolinium-based contrast exposure, nephrogenic systemic fibrosis, and gadolinium detection in tissue. AJR Am J Roentgenol. 2008 Apr;190(4):1060-8.

  • MRI of mandibular osteonecrosis secondary to bisphosphonates. AJR Am J Roentgenol. 2008 Apr;190(4):949-55.

  • Rapid and quantitative DNA analysis of genetic mutations for polycystic kidney disease (PKD) using magnetic/luminescent nanoparticles. Anal Bioanal Chem. 2008 Apr;390(7):1829-35. Epub 2008 Feb 7.

  • Differential regulation of neutrophil CD18 integrin function by di- and tri-valent cations: manganese vs. gadolinium. Ann Biomed Eng. 2008 Apr;36(4):647-60. Epub 2008 Mar 4.

  • Inflammatory biomarkers, disease activity and spinal disease measures in patients with ankylosing spondylitis after treatment with infliximab. Ann Rheum Dis. 2008 Apr;67(4):511-7. Epub 2007 Jul 20.

  • Molecular imaging of {alpha}v{beta}3 integrin expression in atherosclerotic plaques with a mimetic of RGD peptide grafted to Gd-DTPA. Cardiovasc Res. 2008 Apr 1;78(1):148-57. Epub 2008 Jan 3.

  • Preconditioning with death ligands FasL and TNF-alpha protects the cirrhotic mouse liver against ischaemic injury. Gut. 2008 Apr;57(4):492-9. Epub 2007 Dec 13.

  • Black-Blood Diffusion-Weighted EPI Acquisition of the Liver with Parallel Imaging: Comparison with a Standard T2-Weighted Sequence for Detection of Focal Liver Lesions. Invest Radiol. 2008 Apr;43(4):261-266.

  • Left Ventricular Postmyocardial Infarction Remodeling Studied by Combining MR-Tagging With Delayed MR Contrast Enhancement. Invest Radiol. 2008 Apr;43(4):219-228.

  • Synthesis of a new gadolinium complex with a high affinity for human serum albumin and its manifold physicochemical characterization by proton relaxation rate analysis, NMR diffusometry and electrospray mass spectrometry. J Inorg Biochem. 2008 Apr;102(4):721-30. Epub 2007 Nov 17.

  • Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. J Pathol. 2008 Apr;214(5):584-93.

  • Optimized 3D bright blood MRI of aortic plaque at 3 T. Magn Reson Imaging. 2008 Apr;26(3):330-6. Epub 2008 Feb 20.

  • Nephrogenic systemic fibrosis after exposure to gadolinium in patients with renal failure. Nephrol Dial Transplant. 2008 Apr;23(4):1467. No abstract available.

  • Comparison between gadolinium and iodine contrast for percutaneous intervention in atherosclerotic renal artery stenosis: clinical outcomes. Nephrol Dial Transplant. 2008 Apr;23(4):1233-40. Epub 2008 Feb 5.

  • Regulation of stretch-activated ANP secretion by chloride channels. Peptides. 2008 Apr;29(4):613-21. Epub 2007 Dec 8.

  • Iodixanol 320 results in better renal tolerance and radiodensity than do gadolinium-based contrast media: arteriography in ischemic porcine kidneys. Radiology. 2008 Apr;247(1):88-97. Epub 2008 Feb 21.

 

 

Material Safety Data Sheet
  • 1 Identification of substance

    • Product details

    • Trade name Gadolinium acetate
  • 2 Composition/Data on components:

    • Chemical characterization:
                 Designation: (CAS#)                                        
      Gadolinium acetate, hydrate (CAS# ?), 100%
    • Identification number(s):
    • EINECS Number: 240-204-9
  • 3 Hazards identification

    • Hazard designation: · void
    • Information pertaining to particular dangers for man and environment
      Not applicable
  • 4 First aid measures

    • After inhalation
      Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if symptoms persist.
      Seek immediate medical advice.
    • After skin contact
      Instantly wash with water and soap and rinse thoroughly.
      Seek immediate medical advice.
    • After eye contact
      Rinse opened eye for several minutes under running water. Then consult doctor.
    • After swallowing Seek medical treatment.
  • 5 Fire fighting measures

    • Suitable extinguishing agents
      CO2, extinguishing powder or water jet. Fight larger fires with water jet.
    • Special hazards caused by the material, its products of combustion or
        flue gases:
      Can be released in case of fire:
      Carbon monoxide (CO)
    • Protective equipment:
      Wear self-contained breathing apparatus.
      Wear full protective suit.
  • 6 Accidental release measures

    • Person-related safety precautions:
      Wear protective equipment. Keep unprotected persons away.
      Ensure adequate ventilation
    • Measures for environmental protection:
      Do not allow material to be released to the environment without proper governmental permits.
    • Measures for cleaning/collecting: Collect mechanically.
    • Additional information:
      See Section 7 for information on safe handling
      See section 8 for information on personal protection equipment.
      See Section 13 for information on disposal.
  • 7 Handling and storage


    • Handling
    • Information for safe handling:
      Keep containers tightly sealed.
      Store in cool, dry place in tightly closed containers.
      No special precautions necessary if used correctly.
    • Information about protection against explosions and fires:
      No special measures required.

    • Storage
    • Requirements to be met by storerooms and containers:
      No special requirements.
    • Information about storage in one common storage facility:
      Store away from oxidizing agents.
      Store away from water.
    • Further information about storage conditions:
      This product is hygroscopic.
      Protect from humidity and keep away from water.
      Keep container tightly sealed.
      Store in cool, dry conditions in well sealed containers.
  • 8 Exposure controls and personal protection

    • Additional information about design of technical systems:
      Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.

    • Components with critical values that require monitoring at the
      workplace:                                                             
      Not required.
    • Additional information: No data

    • Personal protective equipment
    • General protective and hygienic measures
      The usual precautionary measures should be adhered to in handling the chemicals.
      Keep away from foodstuffs, beverages and food.
      Instantly remove any soiled and impregnated garments.
      Wash hands during breaks and at the end of the work.
    • Breathing equipment: Use breathing protection with high concentrations.
    • Protection of hands: Impervious gloves
    • Eye protection: Safety glasses
    • Body protection: Protective work clothing.
  • 9 Physical and chemical properties:

    • General Information

    • Form: Crystalline
    • Colour: White
    • Smell: Odourless
    •   Value/Range  Unit    Method      
    • Change in condition
    • Melting point/Melting range:       Not determined
    • Boiling point/Boiling range:       Not determined
    • Sublimation temperature / start:   Not determined

    • Flash point:                       Not applicable

    • Ignition temperature:              Not determined

    • Decomposition temperature:         Not determined

    • Danger of explosion:               Product is not explosive.

    • Critical values for explosion:
    • Lower:                             Not determined
    • Upper:                             Not determined

    • Steam pressure:                    Not determined

    • Density                            Not determined

    • Solubility in / Miscibility with
    • Water:                             Slightly soluble
      Not determined
  • 10 Stability and reactivity

    • Thermal decomposition / conditions to be avoided:
      No decomposition if used and stored according to specifications.
    • Materials to be avoided:
      Oxidizing agents
      Water/moisture
      Acids
    • Dangerous reactions: No dangerous reactions known
    • Dangerous products of decomposition:
      Carbon monoxide and carbon dioxide
      Metal oxide
  • 11 Toxicological information

    • Acute toxicity:
    • Primary irritant effect:
    • on the skin: Powder: irritant effect
    • on the eye: Powder: irritant effect
    • Sensitization: No sensitizing effect known.
    • Additional toxicological information:
      To the best of our knowledge the acute and chronic toxicity of this substance is not fully known.
      No classification data on carcinogenic properties of this material is available from the EPA, IARC, NTP, OSHA or ACGIH.
  • 12 Ecological information:

    • General notes:
      Do not allow material to be released to the environment without proper governmental permits.
      Water hazard class 1 (Self-assessment): slightly hazardous for water.
      Do not allow undiluted product or large quantities of it to reach ground water, water bodies or sewage system.
  • 13 Disposal considerations


    • Product:
    • Recommendation
      Consult state, local or national regulations for proper disposal.
      Hand over to disposers of hazardous waste.
      Must be specially treated under adherence to official regulations.

    • Uncleaned packagings:
    • Recommendation:
      Disposal must be made according to official regulations.
  • 14 Transport information


    • Land transport ADR/RID and GGVS/GGVE (cross-border/domestic)
    • ADR/RID-GGVS/E Class:         None

    • Maritime transport IMDG/GGVSea:
    • IMDG/GGVSea Class:        None

    • Air transport ICAO-TI and IATA-DGR:
    • ICAO/IATA Class:          None

    • Transport/Additional information:
      Not dangerous according to the above specifications.
  • 15 Regulatory information


    • Designation according to EC guidelines:
      Observe the normal safety regulations when handling chemicals
      The product is not subject to identification regulations under EC Directives and the Ordinance on Hazardous Materials (GefStoffV).

    • National regulations

    • Information about limitation of use:
      For use only by technically qualified individuals.

    • Water hazard class:
      Water hazard class 1 (Self-assessment): slightly hazardous for water.
  • 16 Other information:

      Employers should use this information only as a supplement to other information gathered by them, and should make independent judgement of suitability of this information to ensure proper use and protect the health and safety of employees.  This information is furnished without warranty, and any use of the product not in conformance with this Material Safety Data Sheet, or in combination with any other product or process, is the responsibility of the user.

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