cis-Dichlorobis(diethylsulfide)platinum(II) is one of numerous organo-metallic compounds sold by American Elements under the tradename AE Organo-MetallicsT. cis-Dichlorobis(diethylsulfide)platinum(II) is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Additional technical, research and safety information is available.
Platinum is a Block D, Group 10, Period 6 element. The number of electrons in each of Platinum's shells is 2, 8, 18, 32, 17, 1 and its electronic configuration is [Xe] 4f14 5d9 6s1. In its elemental form platinum's CAS number is 7440-06-4. The platinum atom has a radius of 137.3.pm and it's Van derWaals radius is 172.pm. Platinum is not toxic. Platinum is a member of the platinum group of metals. It is highly corrosion resistant and has numerous catalytic applications. These include in petrochemical cracking catalysts, automotive catalytic converters and in the processes used for proton exchange membrane fuel cells. The metal does not oxidize in air at any temperature. The metal is extensively used in jewelry, electronic wire, and crucibles for corrosive and high temperature laboratory uses and in many advanced instruments. Platinum compounds have application in medicine. Platinum is available as metal and compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity); metals in the form of foil, sputtering target, and rod, and compounds as submicron and nanopowder. Platinum was first discovered by Julius Scaliger in 1735. The origin of the name comes from the Spanish word platina meaning silver. See Platinum research below.
Sulfur is a Block P, Group 16, Period 3 element. The number of electrons in each of Sulfur's shells is 2, 8, 6 and its electronic configuration is [Ne]3s2 3p4. In its elemental form sulfur's CAS number is 7704-34-9. The sulfur atom has a radius of 100pm and it's Van der Waals radius is 180pm. Sulfur is a crucial element for all life and serves as both fuels and respiratory (oxygen-replacing) materials for simple organisms. In nature, sulfur can be found in hot springs, meteorites, volcanoes, and as galena, gypsum, Epsom salts, and barite. Sulfur, when organically bonded, is a component of all proteins, as the amino acids methionine and cysteine. In organic form, Sulfur is present in the vitamins thiamine and biotin. Sulfur is also a vital part of many enzymes and also in antioxidant molecules like glutathione and thioredoxin.Sulfur is available as compounds with purities from 99% to 99.9999% (ACS grade to ultra-high purity). Sulfur has been known since ancient times but was not accepted as an element until 1777. Antoine Lavoisier helped to convince the scientific commuity that sulfus is an element and not a compound. See Sulfur research below.
PACKAGING SPECIFICATIONS FOR BULK & RESEARCH QUANTITIES
Typical bulk packaging includes palletized plastic 5 gallon/25 kg. pails, fiber and steel drums to 1 ton super sacks in full container (FCL) or truck load (T/L) quantities. Research and sample quantities and hygroscopic, oxidizing or other air sensitive materials may be packaged under argon or vacuum. Shipping documentation includes a Certificate of Analysis and Material Safety Data Sheet (MSDS). Solutions are packaged in polypropylene, plastic or glass jars up to palletized 440 gallon liquid totes.
S-1 Monotherapy for Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck After Progression on Platinum-based Chemotherapy.
Yokota T, Onozawa Y, Boku N, Hamauchi S, Tsushima T, Taniguchi H, Todaka A, Machida N, Yamazaki K, Fukutomi A, Yasui H.
Jpn J Clin Oncol. 2011 Oct 5. [Epub ahead of print]
PMID:
21980053
[PubMed - as supplied by publisher]
Gemcitabine and platinum pathway pharmacogenetics in asian breast cancer patients.
Wong AL, Yap HL, Yeo WL, Soong R, Ng SS, Wang LZ, Cordero MT, Yong WP, Goh BC, Lee SC.
Cancer Genomics Proteomics. 2011 Sep;8(5):255-9.
PMID:
21980041
[PubMed - in process]
Pt-rotaxanes as cytotoxic agents.
Wang X, Smithrud DB.
Bioorg Med Chem Lett. 2011 Sep 16. [Epub ahead of print]
PMID:
21978681
[PubMed - as supplied by publisher]
Effects of solvents on in vitro potencies of platinum compounds.
Yi YW, Bae I.
DNA Repair (Amst). 2011 Oct 4. [Epub ahead of print] No abstract available.
PMID:
21978437
[PubMed - as supplied by publisher]
DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies.
Rezaee M, Alizadeh E, Hunting D, Sanche L.
Bioinorg Chem Appl. 2012;2012:923914. Epub 2011 Oct 2.
PMID:
21977010
[PubMed - in process]
Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in partially platinum-sensitive ovarian cancer patients: results from a subset analysis of the CALYPSO phase III trial.
Gladieff L, Ferrero A, De Rauglaudre G, Brown C, Vasey P, Reinthaller A, Pujade-Lauraine E, Reed N, Lorusso D, Siena S, Helland H, Elit L, Mahner S.
Ann Oncol. 2011 Oct 5. [Epub ahead of print]
PMID:
21976386
[PubMed - as supplied by publisher]
Multiple hydrogen bondings in a platinum complex.
Tabei ES, Samouei H, Rashidi M.
Dalton Trans. 2011 Oct 6. [Epub ahead of print]
PMID:
21975945
[PubMed - as supplied by publisher]
Surgery for early-stage small cell lung cancer.
Schneider BJ, Saxena A, Downey RJ.
J Natl Compr Canc Netw. 2011 Oct;9(10):1132-9.
PMID:
21975913
[PubMed - in process]
Epidermal growth factor receptor blockers for the treatment of ovarian cancer.
Haldar K, Gaitskell K, Bryant A, Nicum S, Kehoe S, Morrison J.
Cochrane Database Syst Rev. 2011 Oct 5;10:CD007927.
PMID:
21975775
[PubMed - in process]
Adjuvant chemotherapy for endometrial cancer after hysterectomy.
Johnson N, Bryant A, Miles T, Hogberg T, Cornes P.
Cochrane Database Syst Rev. 2011 Oct 5;10:CD003175.
PMID:
21975736
[PubMed - in process]
Mechanism and release rates of surface confined cyclodextrin guests.
Mallon CT, Forster RJ, Keyes TE.
Analyst. 2011 Oct 6. [Epub ahead of print]
PMID:
21975325
[PubMed - as supplied by publisher]
Erlotinib Monotherapy for the Maintenance Treatment of Non-Small Cell Lung Cancer after Previous Platinum-Containing Chemotherapy: A NICE Single Technology Appraisal.
Dickson R, Bagust A, Boland A, Blundell M, Davis H, Dundar Y, Hockenhull J, Martin Saborido C, Oyee J, Ramani VS.
Pharmacoeconomics. 2011 Oct 3. [Epub ahead of print]
PMID:
21967156
[PubMed - as supplied by publisher]
Low temperature crystallization of transparent, highly ordered nanoporous SnO(2) thin films: application to room-temperature hydrogen sensing.
Shao S, Qiu X, He D, Koehn R, Guan N, Lu X, Bao N, Grimes CA.
Nanoscale. 2011 Oct 5;3(10):4283-9. Epub 2011 Aug 30.
PMID:
21879121
[PubMed - in process]
Design, synthesis, characterization, luminescence and non-linear optical (NLO) properties of multinuclear platinum(ii) alkynyl complexes.
Chan CK, Tao CH, Li KF, Wong KM, Zhu N, Cheah KW, Yam VW.
Dalton Trans. 2011 Oct 28;40(40):10670-85. Epub 2011 Aug 19.
PMID:
21858294
[PubMed - in process]
Platinum porphyrins as ionophores in polymeric membrane electrodes.
Lvova L, Verrelli G, Stefanelli M, Nardis S, Di Natale C, Amico AD, Makarychev-Mikhailov S, Paolesse R.
Analyst. 2011 Oct 4. [Epub ahead of print]
PMID:
21971176
[PubMed - as supplied by publisher]
Acquired platinum resistance enhances tumour angiogenesis through angiotensin II type 1 receptor in bladder cancer.
Tanaka N, Miyajima A, Kosaka T, Miyazaki Y, Shirotake S, Shirakawa H, Kikuchi E, Oya M.
Br J Cancer. 2011 Oct 4. doi: 10.1038/bjc.2011.399. [Epub ahead of print]
PMID:
21970881
[PubMed - as supplied by publisher]
Preclinical emergence of vandetanib as a potent antitumour agent in mesothelioma: molecular mechanisms underlying its synergistic interaction with pemetrexed and carboplatin.
Giovannetti E, Zucali PA, Assaraf YG, Leon LG, Smid K, Alecci C, Giancola F, Destro A, Gianoncelli L, Lorenzi E, Roncalli M, Santoro A, Peters GJ.
Br J Cancer. 2011 Oct 4. doi: 10.1038/bjc.2011.400. [Epub ahead of print]
PMID:
21970874
[PubMed - as supplied by publisher]
An indirect comparison of the efficacy of bevacizumab plus carboplatin and paclitaxel versus pemetrexed with cisplatin in patients with advanced or recurrent non-squamous adenocarcinoma non-small cell lung cancer.
Nuijten MJ, Aultman R, Carpeño JD, Vergnenègre A, Chouaid C, Walzer S, Siebert U.
Curr Med Res Opin. 2011 Oct 4. [Epub ahead of print]
PMID:
21970659
[PubMed - as supplied by publisher]
Hypersensitivity reactions to anticancer agents: data mining of the public version of the FDA Adverse Event Reporting System, AERS.
Kadoyama K, Kuwahara A, Yamamori M, Brown J, Sakaeda T, Okuno Y.
J Exp Clin Cancer Res. 2011 Oct 5;30(1):93. [Epub ahead of print]
PMID:
21970649
[PubMed - as supplied by publisher]
Reactions of metallodrugs with proteins: selective binding of phosphane-based platinum(ii) dichlorides to horse heart cytochrome c probed by ESI MS coupled to enzymatic cleavage.
Mügge C, Micheucci E, Boscaro F, Gabbiani C, Messori L, Weigand W.
Metallomics. 2011 Oct 4;3(10):987-90. Epub 2011 Sep 22.
PMID:
21947338
[PubMed - in process]
Self-assembly of a sulphur-terminated graphene nanoribbon within a single-walled carbon nanotube.
Chuvilin A, Bichoutskaia E, Gimenez-Lopez MC, Chamberlain TW, Rance GA, Kuganathan N, Biskupek J, Kaiser U, Khlobystov AN.
Nat Mater. 2011 Aug 7. doi: 10.1038/nmat3082. [Epub ahead of print]
PMID:
21822259
[PubMed - as supplied by publisher]
Crystallization and preliminary X-ray analysis of the yeast tRNA-thiouridine modification protein 1 (Tum1p).
Qiu R, Wang F, Liu M, Yang Z, Wu T, Ji C.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 1;67(Pt 8):953-5. Epub 2011 Jul 27.
PMID:
21821903
[PubMed - in process]
Characterization of Bacillus thuringiensis L-isoleucine dioxygenase toward the production of useful amino acids.
Hibi M, Kawashima T, Kodera T, Smirnov SV, Sokolov PM, Sugiyama M, Shimizu S, Yokozeki K, Ogawa J.
Appl Environ Microbiol. 2011 Aug 5. [Epub ahead of print]
PMID:
21821743
[PubMed - as supplied by publisher]
Characterization of the sulfurtransferase family from Oryza sativa L.
Guretzki S, Papenbrock J.
Plant Physiol Biochem. 2011 Jul 23. [Epub ahead of print]
PMID:
21821426
[PubMed - as supplied by publisher]
Development of a small-scale bioreactor method to monitor the molecular diversity and environmental impacts of bacterial biofilm communities from an acid mine drainage impacted creek.
Cole M, Wrubel J, Henegan P, Janzen C, Holt J, Tobin T.
J Microbiol Methods. 2011 Jul 28. [Epub ahead of print]
PMID:
21821067
[PubMed - as supplied by publisher]
In situ incorporation of nickel nanoparticles into the mesopores of MCM-41 by manipulation of solvent-solute interaction and its activity toward adsorptive desulfurization of gas oil.
Samadi-Maybodi A, Teymouri M, Vahid A, Miranbeigi A.
J Hazard Mater. 2011 Jul 6. [Epub ahead of print]
PMID:
21820806
[PubMed - as supplied by publisher]
Stearoyl-CoA desaturase is an essential enzyme for the parasitic protist Trypanosoma brucei.
Alloatti A, Gupta S, Gualdrón-López M, Nguewa PA, Altabe SG, Deumer G, Wallemacq P, Michels PA, Uttaro AD.
Biochem Biophys Res Commun. 2011 Jul 28. [Epub ahead of print]
PMID:
21820408
[PubMed - as supplied by publisher]
The use of multi-element stable isotope analysis to monitor the origin of chondroitin sulfates.
Thomas F, Jamin E, Shimoo K, Nagao J, Osaki Y, Granier C.
Rapid Commun Mass Spectrom. 2011 Sep 15;25(17):2533-7. doi: 10.1002/rcm.5159.
PMID:
21818814
[PubMed - in process]
Sulphur isotopes in animal hair track distance to sea.
Zazzo A, Monahan FJ, Moloney AP, Green S, Schmidt O.
Rapid Commun Mass Spectrom. 2011 Sep 15;25(17):2371-8. doi: 10.1002/rcm.5131.
PMID:
21818798
[PubMed - in process]
Experimental and Theoretical Evidence of Aromatic Behavior in Heterobenzene-Like Molecules with Metal-Metal Multiple Bonds.
Fang W, He Q, Tan ZF, Liu CY, Lu X, Murillo CA.
Chemistry. 2011 Aug 4. doi: 10.1002/chem.201003693. [Epub ahead of print]
PMID:
21818792
[PubMed - as supplied by publisher]
Rhodovulum phaeolacus sp. nov. a phototrophic alphaproteobacterium isolated from a brown pond.
Venkata Naga Satya Lakshmi K, Sasikala C, Venkata Ramana V, Veera Venkata Ramaprasad E, Venkata Ramana C.
J Gen Appl Microbiol. 2011;57(3):145-51.
PMID:
21817826
[PubMed - in process]
Comparative data on effects of leading pretreatments and enzyme loadings and formulations on sugar yields from different switchgrass sources.
Wyman CE, Balan V, Dale BE, Elander RT, Falls M, Hames B, Holtzapple MT, Ladisch MR, Lee YY, Mosier N, Pallapolu VR, Shi J, Thomas SR, Warner RE.
Bioresour Technol. 2011 Jun 21. [Epub ahead of print]
PMID:
21816612
[PubMed - as supplied by publisher]
Target loads of atmospheric sulfur deposition for the protection and recovery of acid-sensitive streams in the Southern Blue Ridge Province.
Sullivan TJ, Cosby BJ, Jackson WA.
J Environ Manage. 2011 Aug 2. [Epub ahead of print]
PMID:
21816535
[PubMed - as supplied by publisher]
Differential effects of a post-anthesis fertilizer regimen on the wheat flour proteome determined by quantitative 2-DE.
Altenbach SB, Tanaka CK, Hurkman WJ, Whitehand LC, Vensel WH, Dupont FM.
Proteome Sci. 2011 Aug 4;9(1):46. [Epub ahead of print]
PMID:
21816081
[PubMed - as supplied by publisher]
Comparative toxicity of arsenic metabolites in human bladder cancer EJ-1 cells.
Naranmandura H, Michael CW, Xu S, Lee J, Leslie E, Weinfeld M, Le XC.
Chem Res Toxicol. 2011 Aug 4. [Epub ahead of print]
PMID:
21815631
[PubMed - as supplied by publisher]
The Effects of Different Garlic-derived Allyl Sulfides on Peroxidative Processes and Anaerobic Sulfur Metabolism in Mouse Liver.
Iciek MB, Kowalczyk-Pachel D, Kwiecien I, Dudek MB.
Phytother Res. 2011 Aug 4. doi: 10.1002/ptr.3572. [Epub ahead of print]
PMID:
21815229
[PubMed - as supplied by publisher]
A combined model of hepatic polyamine and sulfur amino acid metabolism to analyze S-adenosyl methionine availability.
Reyes-Palomares A, Montañez R, Sánchez-Jiménez F, Medina MA.
Amino Acids. 2011 Aug 4. [Epub ahead of print]
PMID:
21814788
[PubMed - as supplied by publisher]
Microbial gene functions enriched in the Deepwater Horizon deep-sea oil plume.
Lu Z, Deng Y, Van Nostrand JD, He Z, Voordeckers J, Zhou A, Lee YJ, Mason OU, Dubinsky EA, Chavarria KL, Tom LM, Fortney JL, Lamendella R, Jansson JK, D'haeseleer P, Hazen TC, Zhou J.
ISME J. 2011 Aug 4. doi: 10.1038/ismej.2011.91. [Epub ahead of print]
PMID:
21814288
[PubMed - as supplied by publisher]
1,1'-(3-Methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a Building Block in Heterocyclic Synthesis. Novel Synthesis of Some Pyrazole and Pyrimidine Derivatives.
Mabkhot YN, Al-Majid AM, Barakat A, Alshahrani S, Siddiqui Y.
Molecules. 2011 Aug 3;16(8):6502-11.
PMID:
21814162
[PubMed - in process]
Towards the Growth of an Aligned Single-Layer MoS2 Film.
Kim D, Sun D, Lu W, Cheng Z, Zhu Y, Le D, Rahman TS, Bartels L.
Langmuir. 2011 Aug 3. [Epub ahead of print]
PMID:
21812475
[PubMed - as supplied by publisher]
Platinum is a Block D, Group 10, Period 6 element. The number of electrons in each of Platinum's shells is 2, 8, 18, 32, 17, 1 and its electronic configuration is [Xe] 4f14 5d9 6s1. In its elemental form platinum's CAS number is 7440-06-4. The platinum atom has a radius of 137.3.pm and it's Van derWaals radius is 172.pm. Platinum is not toxic. Platinum is a member of the platinum group of metals. It is highly corrosion resistant and has numerous catalytic applications. These include in petrochemical cracking catalysts, automotive catalytic converters and in the processes used for proton exchange membrane 
not oxidize in air at any
temperature. The metal is extensively used in jewelry, electronic wire, and crucibles for corrosive and high temperature laboratory uses and in many advanced instruments. Platinum compounds have application in medicine. Platinum is available as metal and compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity); metals in the form of foil, sputtering target, and rod, and compounds as submicron and nanopowder. Platinum was first discovered by Julius Scaliger in 1735. The origin of the name comes from the Spanish word platina meaning silver. See Platinum research below.
Sulfur is a Block P, Group 16, Period 3 element. The number of electrons in each of Sulfur's shells is 2, 8, 6 and its electronic configuration is [Ne]3s2 3p4. In its elemental form sulfur's CAS number is 7704-34-9. The sulfur atom has a radius of 100pm and it's Van der Waals radius is 180pm. Sulfur is a crucial element for all life and serves as both fuels and respiratory (oxygen-replacing) materials for simple organisms. In nature, sulfur can be found in hot springs, meteorites, volcanoes, and as galena, gypsum, Epsom salts, and barite. Sulfur, when organically bonded, is a component of all proteins, as the amino acids methionine 
and cysteine. In organic form, Sulfur is present in the vitamins thiamine and biotin. Sulfur is also a vital part of many enzymes and also in antioxidant molecules like glutathione and thioredoxin.Sulfur is available as compounds with purities from 99% to 99.9999% (ACS grade to ultra-high purity). Sulfur has been known since ancient times but was not accepted as an element until 1777. Antoine Lavoisier helped to convince the scientific commuity that sulfus is an element and not a compound. See Sulfur research below. 
