Sodium Hexahydroxyplatinate(IV) is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Iodide compounds are used in internal medicine. Treating an iodide with Platinum dioxide and sulfuric acid sublimes the iodine.American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia)and follows applicable ASTM testing standards.Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement.
Sodium is a Block S, Group 1, Period 3 element. The number of electrons in each of Sodium's shells is 2, 8, 1 and its electronic configuration is [Ne] 3s1. In its elemental form sodium's CAS number is 7440-23-5. The sodium atom has a radius of 185.8.pm and it's Van der Waalsradius is 227.pm. Sodium is not toxic but skin contact may cause irritation and burns. Sodium is primarily used in its metallic form in the production of chemical esters and in the manufacturing of various other organic compounds. The metal is used in the alloy of tin, nickel and copper for its structural characteristics. Sodium is availableas metal and compounds with purities from 99% to 99.9999% (ACS grade to ultra-high purity); metals in the form of foil, sputtering target, and rod, and compounds as submicron and nanopowder. High purity sodium compounds are used as reducing agents. Sodium compounds are used in low tech applications throughout industry. Sodium was first discovered by Sir Humphrey Davy in 1807. The name Sodium comes from the Latin word "natrium" which means sodium carbonate. See Sodium research below.
Platinum is a Block D, Group 10, Period 6 element. The number of electrons in each of Platinum's shells is 2, 8, 18, 32, 17, 1 and its electronic configuration is [Xe] 4f14 5d9 6s1. In its elemental form platinum's CAS number is 7440-06-4. The platinum atom has a radius of 137.3.pm and it's Van derWaals radius is 172.pm. Platinum is not toxic. Platinum is a member of the platinum group of metals. It is highly corrosion resistant and has numerous catalytic applications. These include in petrochemical cracking catalysts, automotive catalytic converters and in the processes used for proton exchange membrane fuel cells. The metal does not oxidize in air at any temperature. The metal is extensively used in jewelry, electronic wire, and crucibles for corrosive and high temperature laboratory uses and in many advanced instruments. Platinum compounds have application in medicine. Platinum is available as metal and compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity); metals in the form of foil, sputtering target, and rod, and compounds as submicron and nanopowder. Platinum was first discovered by Julius Scaliger in 1735. The origin of the name comes from the Spanish word platina meaning silver. See Platinum research below.
PACKAGING SPECIFICATIONS FOR BULK & RESEARCH QUANTITIES
Typical bulk packaging includes palletized plastic 5 gallon/25 kg. pails, fiber and steel drums to 1 ton super sacks in full container (FCL) or truck load (T/L) quantities. Research and sample quantities and hygroscopic, oxidizing or other air sensitive materials may be packaged under argon or vacuum. Shipping documentation includes a Certificate of Analysis and Material Safety Data Sheet (MSDS). Solutions are packaged in polypropylene, plastic or glass jars up to palletized 440 gallon liquid totes.
Natural history of Christianson syndrome.
Schroer RJ, Holden KR, Tarpey PS, Matheus MG, Griesemer DA, Friez MJ, Fan JZ, Simensen RJ, Strømme P, Stevenson RE, Stratton MR, Schwartz CE.
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Gemcitabine and platinum pathway pharmacogenetics in asian breast cancer patients.
Wong AL, Yap HL, Yeo WL, Soong R, Ng SS, Wang LZ, Cordero MT, Yong WP, Goh BC, Lee SC.
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21980041
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Pt-rotaxanes as cytotoxic agents.
Wang X, Smithrud DB.
Bioorg Med Chem Lett. 2011 Sep 16. [Epub ahead of print]
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Effects of solvents on in vitro potencies of platinum compounds.
Yi YW, Bae I.
DNA Repair (Amst). 2011 Oct 4. [Epub ahead of print] No abstract available.
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DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies.
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Gladieff L, Ferrero A, De Rauglaudre G, Brown C, Vasey P, Reinthaller A, Pujade-Lauraine E, Reed N, Lorusso D, Siena S, Helland H, Elit L, Mahner S.
Ann Oncol. 2011 Oct 5. [Epub ahead of print]
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Multiple hydrogen bondings in a platinum complex.
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Surgery for early-stage small cell lung cancer.
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Erlotinib Monotherapy for the Maintenance Treatment of Non-Small Cell Lung Cancer after Previous Platinum-Containing Chemotherapy: A NICE Single Technology Appraisal.
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Low temperature crystallization of transparent, highly ordered nanoporous SnO(2) thin films: application to room-temperature hydrogen sensing.
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Design, synthesis, characterization, luminescence and non-linear optical (NLO) properties of multinuclear platinum(ii) alkynyl complexes.
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Platinum porphyrins as ionophores in polymeric membrane electrodes.
Lvova L, Verrelli G, Stefanelli M, Nardis S, Di Natale C, Amico AD, Makarychev-Mikhailov S, Paolesse R.
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21971176
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Acquired platinum resistance enhances tumour angiogenesis through angiotensin II type 1 receptor in bladder cancer.
Tanaka N, Miyajima A, Kosaka T, Miyazaki Y, Shirotake S, Shirakawa H, Kikuchi E, Oya M.
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Preclinical emergence of vandetanib as a potent antitumour agent in mesothelioma: molecular mechanisms underlying its synergistic interaction with pemetrexed and carboplatin.
Giovannetti E, Zucali PA, Assaraf YG, Leon LG, Smid K, Alecci C, Giancola F, Destro A, Gianoncelli L, Lorenzi E, Roncalli M, Santoro A, Peters GJ.
Br J Cancer. 2011 Oct 4. doi: 10.1038/bjc.2011.400. [Epub ahead of print]
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21970874
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An indirect comparison of the efficacy of bevacizumab plus carboplatin and paclitaxel versus pemetrexed with cisplatin in patients with advanced or recurrent non-squamous adenocarcinoma non-small cell lung cancer.
Nuijten MJ, Aultman R, Carpeño JD, Vergnenègre A, Chouaid C, Walzer S, Siebert U.
Curr Med Res Opin. 2011 Oct 4. [Epub ahead of print]
PMID:
21970659
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Hypersensitivity reactions to anticancer agents: data mining of the public version of the FDA Adverse Event Reporting System, AERS.
Kadoyama K, Kuwahara A, Yamamori M, Brown J, Sakaeda T, Okuno Y.
J Exp Clin Cancer Res. 2011 Oct 5;30(1):93. [Epub ahead of print]
PMID:
21970649
[PubMed - as supplied by publisher]
Reactions of metallodrugs with proteins: selective binding of phosphane-based platinum(ii) dichlorides to horse heart cytochrome c probed by ESI MS coupled to enzymatic cleavage.
Mügge C, Micheucci E, Boscaro F, Gabbiani C, Messori L, Weigand W.
Metallomics. 2011 Oct 4;3(10):987-90. Epub 2011 Sep 22.
PMID:
21947338
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