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Periodic table of the elements science and academic information, elements and advanced materials data, scientific presentations and all pages, designs, concepts, logos, and color schemes herein are the copyrighted proprietary rights and intellectual property of American Elements. American Elements is a U.S. Registered Trademark. © 2001-2009. American Elements. All rights reserved. |
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Recent Research & Development for Samarium
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Enantiopure Aminopyrans by a Lewis Acid Promoted Rearrangement of 1,2-Oxazines: Versatile Building Blocks for Oligosaccharide and Sugar Amino Acid Mimetics.
Al-Harrasi A, Pfrengle F, Prisyazhnyuk V, Yekta S, Koós P, Reissig HU.
Chemistry. 2009 Sep 24. [Epub ahead of print]
PMID: 19780107 [PubMed - as supplied by publisher]
- Synthesis, Structure, and Reaction Chemistry of Samarium(II), Europium(II), and Ytterbium(II) Complexes of the Unsymmetrical Benzamidinate Ligand [PhC(NSiMe(3))(NC(6)H(3)Pr(i)(2)-2,6)](-).
Yao S, Chan HS, Lam CK, Lee HK.
Inorg Chem. 2009 Sep 16. [Epub ahead of print]
PMID: 19757783 [PubMed - as supplied by publisher]
- Our experience on pain palliation of bone metastasis with Sr-89 or Sm-153 in cancer patients resistant to a conventional analgesic therapy. A retrospective study.
Montesano T, Giacomobono S, Acqualagna G, Colandrea M, Di Nicola A, Travascio L, Giancamerla M, D'Apollo R, Toteda M, Ugolini F, Filesi M, Ronga G.
Clin Ter. 2009 May-Jun;160(3):193-9.
PMID: 19756320 [PubMed - in process]
- Effect of the thermodynamic properties of W/O microemulsions on samarium oxide nanoparticle size.
Zhu W, Xu L, Ma J, Yang R, Chen Y.
J Colloid Interface Sci. 2009 Aug 12. [Epub ahead of print]
PMID: 19740477 [PubMed - as supplied by publisher]
- SmI(2)-mediated carbon-carbon bond fragmentation in alpha-aminomethyl malonates.
Xu Q, Cheng B, Ye X, Zhai H.
Org Lett. 2009 Sep 17;11(18):4136-8.
PMID: 19739686 [PubMed - in process]
- Spectrofluorimetric assessment of Ramipril using optical sensor Samarium ion-doxycycline complex doped in sol-gel matrix.
Attia MS.
J Pharm Biomed Anal. 2009 Aug 22. [Epub ahead of print]
PMID: 19735989 [PubMed - as supplied by publisher]
- Expression, purification, crystallization and preliminary X-ray analysis of the N-terminal domain of GNBP3 from Drosophila melanogaster.
Mishima Y, Coste F, Bobezeau V, Hervouet N, Kellenberger C, Roussel A.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Sep 1;65(Pt 9):870-3. Epub 2009 Aug 20.
PMID: 19724120 [PubMed - in process]
- Samarium diiodide mediated reactions in total synthesis.
Nicolaou KC, Ellery SP, Chen JS.
Angew Chem Int Ed Engl. 2009;48(39):7140-65.
PMID: 19714695 [PubMed - in process]
- Tandem SmI2-induced nitrone beta-elimination/aldol-type reaction.
Racine E, Py S.
Org Biomol Chem. 2009 Sep 7;7(17):3385-7. Epub 2009 Jul 15.
PMID: 19675890 [PubMed - in process]
- Treatment of painful bone metastases in hormone-refractory prostate cancer with zoledronic acid and samarium-153-ethylenediaminetetramethylphosphonic acid combined.
Lam MG, de Klerk JM, Zonnenberg BA.
J Palliat Med. 2009 Jul;12(7):649-51.
PMID: 19594354 [PubMed - in process]
- Medium-sized carbocycles by samarium diiodide-induced carbonyl-alkene cyclizations.
Saadi J, Lentz D, Reissig HU.
Org Lett. 2009 Aug 6;11(15):3334-7.
PMID: 19583214 [PubMed - in process]
- A new approach to 3-hydroxyprolinol derivatives by samarium diiodide-mediated reductive coupling of chiral nitrone with carbonyl compounds.
Wu SF, Zheng X, Ruan YP, Huang PQ.
Org Biomol Chem. 2009 Jul 21;7(14):2967-75. Epub 2009 Jun 2.
PMID: 19582307 [PubMed - in process]
- Monodisperse samarium and cerium orthovanadate nanocrystals and metal oxidation states on the nanocrystal surface.
Nguyen TD, Dinh CT, Do TO.
Langmuir. 2009 Sep 15;25(18):11142-8.
PMID: 19572496 [PubMed - in process]
- Stabilization of Imidosamarium(III) Cubane by Amidinates.
Pan CL, Chen W, Song S, Zhang H, Li X.
Inorg Chem. 2009 Jun 24. [Epub ahead of print]
PMID: 19552452 [PubMed - as supplied by publisher]
- A novel tetraazamacrocycle bearing a thiol pendant arm for labeling biomolecules with radiolanthanides.
Lacerda S, Campello MP, Marques F, Gano L, Kubícek V, Fousková P, Tóth E, Santos I.
Dalton Trans. 2009 Jun 21;(23):4509-18. Epub 2009 Apr 9.
PMID: 19488449 [PubMed - indexed for MEDLINE]
- Evaluation of a method for activity estimation in Sm-153 EDTMP imaging.
Vanzi E, Genovesi D, Di Martino F.
Med Phys. 2009 Apr;36(4):1219-29.
PMID: 19472629 [PubMed - indexed for MEDLINE]
- Percutaneous tumor curettage and interstitial delivery of samarium-153 coupled with kyphoplasty for treatment of vertebral metastases.
Cardoso ER, Ashamalla H, Weng L, Mokhtar B, Ali S, Macedon M, Guirguis A.
J Neurosurg Spine. 2009 Apr;10(4):336-42.
PMID: 19441992 [PubMed - indexed for MEDLINE]
- Bone marrow recovery following use of systemic (153)Sm-lexidronam and (89)Sr-chloride for bone pain palliation after myelosuppressive therapy.
Papatheofanis FJ, Najib MM.
Int J Radiat Biol. 2009 May;85(5):448-53.
PMID: 19437245 [PubMed - indexed for MEDLINE]
- Selective reductions of cyclic 1,3-diesters using SmI(2) and H(2)O.
Guazzelli G, De Grazia S, Collins KD, Matsubara H, Spain M, Procter DJ.
J Am Chem Soc. 2009 Jun 3;131(21):7214-5.
PMID: 19422232 [PubMed - indexed for MEDLINE]
- Phase I study of concurrent weekly docetaxel and repeated samarium-153 lexidronam in patients with castration-resistant metastatic prostate cancer.
Tu SM, Mathew P, Wong FC, Jones D, Johnson MM, Logothetis CJ.
J Clin Oncol. 2009 Jul 10;27(20):3319-24. Epub 2009 May 4.
PMID: 19414670 [PubMed - indexed for MEDLINE]
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Material Safety Data Sheet |
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1 Identification of substance
- Product details
- Trade name Samarium nitrate
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2 Composition/Data on components:
- Chemical characterization:
Designation: (CAS#)
Samarium nitrate, hexahydrate (CAS# 13759-83-6), 100%
- Identification number(s):
- EINECS Number: 233-796-5
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3 Hazards identification
- Hazard designation:
Xi Irritant
O Oxidising
- Information pertaining to particular dangers for man and environment
R 8 Contact with combustible material may cause fire.
R 36/37/38 Irritating to eyes, respiratory system and skin.
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4 First aid measures
- After inhalation
Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if symptoms persist.
Seek immediate medical advice.
- After skin contact
Instantly wash with water and soap and rinse thoroughly.
Seek immediate medical advice.
- After eye contact
Rinse opened eye for several minutes under running water. Then consult doctor.
- After swallowing Seek immediate medical advice.
- Information for doctor
- The following symptoms may occur:
Dazed
Cramp
Gastric or intestinal trouble
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5 Fire fighting measures
- Suitable extinguishing agents
CO2, extinguishing powder or water jet. Fight larger fires with water jet.
- Special hazards caused by the material, its products of combustion or
flue gases:
This substance is an oxidizer and its heat of reaction with reducing agents or combustibles may cause ignition.
Can be released in case of fire:
Nitrogen oxides (NOx)
- Protective equipment:
Wear self-contained breathing apparatus.
Wear full protective suit.
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6 Accidental release measures
- Person-related safety precautions:
Wear protective equipment. Keep unprotected persons away.
Ensure adequate ventilation
- Measures for environmental protection:
Do not allow material to be released to the environment without proper governmental permits.
- Measures for cleaning/collecting: Ensure adequate ventilation.
- Additional information:
See Section 7 for information on safe handling
See section 8 for information on personal protection equipment.
See Section 13 for information on disposal.
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7 Handling and storage
- Handling
- Information for safe handling:
Keep containers tightly sealed.
Store in cool, dry place in tightly closed containers.
Ensure good ventilation/exhaustion at the workplace.
- Information about protection against explosions and fires:
Substance/product can reduce the ignition temperature of flammable substances.
This substance is an oxidizer and its heat of reaction with reducing agents or combustibles may cause ignition.
- Storage
- Requirements to be met by storerooms and containers:
No special requirements.
- Information about storage in one common storage facility:
Store away from flammable substances.
Store away from reducing agents.
- Further information about storage conditions:
Keep container tightly sealed.
Store in cool, dry conditions in well sealed containers.
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8 Exposure controls and personal protection
- Additional information about design of technical systems:
Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.
- Components with critical values that require monitoring at the
workplace:
Not required.
- Additional information: No data
- Personal protective equipment
- General protective and hygienic measures
The usual precautionary measures should be adhered to in handling the chemicals.
Keep away from foodstuffs, beverages and food.
Instantly remove any soiled and impregnated garments.
Wash hands during breaks and at the end of the work.
Avoid contact with the eyes and skin.
- Breathing equipment: Use breathing protection with high concentrations.
- Protection of hands: Impervious gloves
- Eye protection:
Safety glasses
Face protection
- Body protection: Protective work clothing.
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9 Physical and chemical properties:
- General Information
- Form: Crystalline
- Colour: Yellow
- Smell: Odourless
- Value/Range Unit Method
- Change in condition
- Melting point/Melting range: 78-79 ° C
- Boiling point/Boiling range: Not determined
- Sublimation temperature / start: Not determined
- Flash point: Not applicable
- Inflammability (solid, gaseous)
Contact with combustible material may cause fire.
- Ignition temperature: Not determined
- Decomposition temperature: Not determined
- Critical values for explosion:
- Lower: Not determined
- Upper: Not determined
- Steam pressure: Not determined
- Density at 20 ° C 2.375 g/cm³
- Solubility in / Miscibility with
- Water: Soluble
Fully miscible
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10 Stability and reactivity
- Thermal decomposition / conditions to be avoided:
No decomposition if used and stored according to specifications.
- Materials to be avoided:
Reducing agents, easily oxidized materials
Organic materials
Bases
Acids
- Dangerous reactions:
Reacts with reducing agents
Reacts with flammable substances
- Dangerous products of decomposition:
Nitrous vitriol gases
Metal oxide
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11 Toxicological information
- Acute toxicity:
LD/LC50 values that are relevant for classification:
Oral: LD50: 2160 mg/kg (rat)
- Primary irritant effect:
- on the skin: Irritant for skin and mucous membranes.
- on the eye: Irritant effect.
- Sensitization: No sensitizing effect known.
- Additional toxicological information:
To the best of our knowledge the acute and chronic toxicity of this substance is not fully known.
No classification data on carcinogenic properties of this material is available from the EPA, IARC, NTP, OSHA or ACGIH.
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12 Ecological information:
- General notes:
Do not allow material to be released to the environment without proper governmental permits.
Water hazard class 1 (Self-assessment): slightly hazardous for water.
Do not allow undiluted product or large quantities of it to reach ground water, water bodies or sewage system.
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13 Disposal considerations
- Product:
- Recommendation
Consult state, local or national regulations for proper disposal.
Hand over to disposers of hazardous waste.
Must be specially treated under adherence to official regulations.
- Uncleaned packagings:
- Recommendation:
Disposal must be made according to official regulations.
- Recommended cleaning agent: Water, if necessary with cleaning agent.
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14 Transport information
- Land transport ADR/RID and GGVS/GGVE (cross-border/domestic)
- ADR/RID-GGVS/E Class: 5.1 (O2) Oxidizing substances.
- Kemler Number: 50
- UN-Number: 1477
- Packaging group: III
- Label 5.1
- Designation of goods: 1477 NITRATES, INORGANIC, N.O.S. (samarium
nitrate)
- Maritime transport IMDG/GGVSea:
- IMDG/GGVSea Class: 5.1
- UN Number: 1477
- Label 5.1
- Packaging group: III
- Correct technical name: NITRATES, INORGANIC, N.O.S.
- Air transport ICAO-TI and IATA-DGR:
- ICAO/IATA Class: 5.1
- UN/ID Number: 1477
- Label 5.1
- Packaging group: III
- Correct technical name: NITRATES, INORGANIC, N.O.S.
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15 Regulatory information
- Designation according to EC guidelines:
- Code letter and hazard designation of product:
Xi Irritant O Oxidising
- Risk phrases:
8 Contact with combustible material may cause fire.
36/37/38 Irritating to eyes, respiratory system and skin.
- Safety phrases:
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
- National regulations
- Information about limitation of use:
For use only by technically qualified individuals.
Employment restrictions concerning young persons must be observed.
- Water hazard class:
Water hazard class 1 (Self-assessment): slightly hazardous for water.
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16 Other information:
Employers should use this information only as a supplement to other information gathered by them, and should make independent judgement of suitability of this information to ensure proper use and protect the health and safety of employees. This information is furnished without warranty, and any use of the product not in conformance with this Material Safety Data Sheet, or in combination with any other product or process, is the responsibility of the user.
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