About Oxalates

Structure of an Oxalate Anion

Oxalate is an anion with the formula C2O2-4, also written [(COO)2]2-. The ion forms salts or coordination complexes with many metals. The oxalate salts of alkali earth metals, such as calcium oxalate, a major component of human kidney stones that is also found in some plants as sharp crystals known as raphides, are insoluble in water and irritating to the skin and digestive tract. Calcium oxalate is used in the production of ceramics, while strontium oxalate and barium oxalate are used as reducing agents in laboratory chemistry and pyrotechnics.

Other oxalates used as chemical reagents include potassium hydrogenoxalate, also known as salt of sorrel, due to its occurrence in the sorrel plant. It is used in photography and for the removal of ink stains. Ferric oxalate is a chemical compound used in platinum printmaking, while cobalt oxalate is used in the production of cobalt catalysts. Oxalates may also be used in some instances as sources of the metals they contain.

Recent Research & Development for Oxalates

The preventive and therapeutic effects of α-lipoic acid on ethylene glycol-induced calcium oxalate deposition in rats., Wang, Zhenghao, Bai Yunjin, Wang Jiahao, and Wang Jia , Int Urol Nephrol, 2020 Mar 04, (2020)

The teleost fish intestine is a major oxalate-secreting epithelium., Whittamore, Jonathan M. , J Exp Biol, 2020 Mar 02, (2020)

Tannin-derived micro-mesoporous carbons prepared by one-step activation with potassium oxalate and CO., Phuriragpitikhon, Jenjira, Ghimire Pramila, and Jaroniec Mietek , J Colloid Interface Sci, 2020 Jan 15, Volume 558, p.55-67, (2020)

The enhanced effect of oxalic acid on the electroreduction of Cr(VI) via formation of intermediate Cr(VI)-oxalate complex., Liu, Yijie, Xin Shuaishuai, and Jiang Bo , Environ Technol, 2020 Jan, Volume 41, Issue 4, p.430-439, (2020)

Active Phagocytosis and Diachronic Processing of Calcium Oxalate Monohydrate Crystals in an in vitro Macrophage Model., Okada, Atsushi, Aoki Hiromasa, Onozato Daichi, Kato Taiki, Hashita Tadahiro, Takase Hiroshi, Sugino Teruaki, Unno Rei, Taguchi Kazumi, Hamamoto Shuzo, et al. , Kidney Blood Press Res, 2019 Sep 11, p.1-12, (2019)

Nanoporous NiP Evolutionarily Structured onto a Ni Foam for Highly Selective Hydrogenation of Dimethyl Oxalate to Methyl Glycolate., Zhu, Jian, Cao Liqun, Li Cuiyu, Zhao Guofeng, Zhu Tong, Hu Wei, Sun Weidong, and Lu Yong , ACS Appl Mater Interfaces, 2019 Oct 01, (2019)

Exosomes from miR-20b-3p-overexpressing stromal cells ameliorate calcium oxalate deposition in rat kidney., Shi, Jing, Duan Junyao, Gong Huijie, Pang Yuewen, Wang Ling, and Yan Yongji , J Cell Mol Med, 2019 Nov, Volume 23, Issue 11, p.7268-7278, (2019)

Oxalate-degrading bacteria, including Oxalobacter formigenes, colonise the gastrointestinal tract of healthy koalas (Phascolarctos cinereus) and those with oxalate nephrosis., Speight, K N., Houston-Francis M, Mohammadi-Dehcheshmeh M, Ebrahimie E, Saputra S, and Trott D J. , Aust Vet J, 2019 May, Volume 97, Issue 5, p.166-170, (2019)

Mechanisms of plant protection against two oxalate-producing fungal pathogens by oxalotrophic strains of Stenotrophomonas spp., Marina, María, Romero Fernando M., Villarreal Natalia M., Medina Andrés J., Gárriz Andrés, Rossi Franco R., Martinez Gustavo A., and Pieckenstain Fernando L. , Plant Mol Biol, 2019 Jun 12, (2019)

Porous CoC₂O₄/Graphene Oxide Nanocomposite for Advanced Potassium-Ion Storage., Wang, Lifeng, Wei Kaiyuan, Zhang Pengjun, Wang Hong, Qi Xiujun, Wu Xuan, Zhao Wei, and Ju Zhicheng , J Nanosci Nanotechnol, 2019 Jun 01, Volume 19, Issue 6, p.3610-3615, (2019)

Mitochondria Permeability Transition versus Necroptosis in Oxalate-Induced AKI., Mulay, Shrikant Ramesh, Honarpisheh Mohsen M., Foresto-Neto Orestes, Shi Chongxu, Desai Jyaysi, Zhao Zhi Bo, Marschner Julian A., Popper Bastian, Buhl Ewa Miriam, Boor Peter, et al. , J Am Soc Nephrol, 2019 Jul 11, (2019)

Efficacy and safety of bupropion hydrochloride extended-release versus escitalopram oxalate in Chinese patients with major depressive disorder: Results from a randomized, double-blind, non-inferiority trial., Shen, Yifeng, Zhao Qian, Yu Yimin, Tan Yunlong, Zhang Honggeng, Xu Xiufeng, Wang Zhiyang, Li Yan, Hu Jingqiu, Zhong Jinhua, et al. , J Affect Disord, 2019 Jul 05, Volume 257, p.143-149, (2019)

Modulatory effects of fibronectin on calcium oxalate crystallization, growth, aggregation, adhesion on renal tubular cells, and invasion through extracellular matrix., Khamchun, Supaporn, Sueksakit Kanyarat, Chaiyarit Sakdithep, and Thongboonkerd Visith , J Biol Inorg Chem, 2019 Jan 30, (2019)

Daily Green Tea Infusions in Hypercalciuric Renal Stone Patients: No Evidence for Increased Stone Risk Factors or Oxalate-Dependent Stones., Rode, Julie, Bazin Dominique, Dessombz Arnaud, Benzerara Yahia, Letavernier Emmanuel, Tabibzadeh Nahid, Hoznek Andras, Tligui Mohamed, Traxer Olivier, Daudon Michel, et al. , Nutrients, 2019 Jan 24, Volume 11, Issue 2, (2019)