About Oxalates

Structure of an Oxalate Anion

Oxalate is an anion with the formula C2O2-4, also written [(COO)2]2-. The ion forms salts or coordination complexes with many metals. The oxalate salts of alkali earth metals, such as calcium oxalate, a major component of human kidney stones that is also found in some plants as sharp crystals known as raphides, are insoluble in water and irritating to the skin and digestive tract. Calcium oxalate is used in the production of ceramics, while strontium oxalate and barium oxalate are used as reducing agents in laboratory chemistry and pyrotechnics.

Other oxalates used as chemical reagents include potassium hydrogenoxalate, also known as salt of sorrel, due to its occurrence in the sorrel plant. It is used in photography and for the removal of ink stains. Ferric oxalate is a chemical compound used in platinum printmaking, while cobalt oxalate is used in the production of cobalt catalysts. Oxalates may also be used in some instances as sources of the metals they contain.

Recent Research & Development for Oxalates

Electrochemiluminescent competitive immunosensor based on polyethyleneimine capped SiO2 nanomaterials as labels to release Ru(bpy)32+ fixed in 3D Cu/Ni oxalate for the detection of aflatoxin B1., Wang, Yaoguang, Zhao Guanhui, Li Xiaojian, Liu Li, Cao Wei, and Wei Qin , Biosens Bioelectron, 2018 Mar 15, Volume 101, p.290-296, (2018)

CO oxidative coupling to dimethyl oxalate over Pd-Me (Me = Cu, Al) catalysts: a combined DFT and kinetic study., Han, Bingying, Feng Xue, Ling Lixia, Fan Maohong, Liu Ping, Zhang Riguang, and Wang Baojun , Phys Chem Chem Phys, 2018 Mar 07, Volume 20, Issue 10, p.7317-7332, (2018)

Colorimetric sensing of oxalate based on its inhibitory effect on the reaction of Fe (III) with curcumin nanoparticles., Pourreza, Nahid, Lotfizadeh Neda, and Golmohammadi Hamed , Spectrochim Acta A Mol Biomol Spectrosc, 2018 Mar 05, Volume 192, p.251-256, (2018)

Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats., Albert, Abhishek, Tiwari Vidhi, Paul Eldho, Ponnusamy Sasikumar, Ganesan Divya, Prabhakaran Rajkumar, Sivakumar Selvi Mariaraj, and Sadasivam Selvam Govindan , Toxicol Mech Methods, 2018 Mar, Volume 28, Issue 3, p.195-204, (2018)

Quantum Spin Liquid from a Three-Dimensional Copper-Oxalate Framework., Zhang, Bin, Baker Peter J., Zhang Yan, Wang Dongwei, Wang Zheming, Su Shaokui, Zhu Daoben, and Pratt Francis L. , J Am Chem Soc, 2018 Jan 10, Volume 140, Issue 1, p.122-125, (2018)

Reactive Silver Oxalate Ink Composition with Enhanced Curing Conditions for Flexible Substrates., Zope, Khushbu Ramesh, Cormier Denis D., and Williams Scott , ACS Appl Mater Interfaces, 2018 Jan 05, (2018)

Does green tea consumption increase urinary oxalate excretion? Results of a prospective trial in healthy men., Chen, Kang, Chen Dong, Lan Chuangxin, Liang Xiongfa, Zeng Tao, Huang Jian, Duan Xiaolu, Kong Zhenzhen, Li Shujue, Tiselius Hans-Göran, et al. , Int Urol Nephrol, 2018 Jan, Volume 50, Issue 1, p.29-33, (2018)

Electrorheological Fluids with High Shear Stress Based on Wrinkly Tin Titanyl Oxalate., Wu, Jinghua, Zhang Lei, Xin Xing, Zhang Yang, Wang Hui, Sun Aihua, Cheng Yuchuan, Chen Xinde, and Xu Gaojie , ACS Appl Mater Interfaces, 2018 Feb 12, (2018)

Regulation of bone mineral density in the grey squirrel, Sciurus carolinensis: Bioavailability of calcium oxalate, and implications for bark stripping., Nichols, C P., Gregory N G., Goode N, Gill R M. A., and Drewe J A. , J Anim Physiol Anim Nutr (Berl), 2018 Feb, Volume 102, Issue 1, p.330-336, (2018)

Protective Effects of Pistacia lentiscus L. fruit extract against calcium oxalate monohydrate induced proximal tubular injury., Cheraft-Bahloul, Nassima, Husson Cécile, Ourtioualous Meriam, Sinaeve Sébastien, Atmani Djebbar, Stévigny Caroline, Nortier Joëlle L., and Antoine Marie-Hélène , J Ethnopharmacol, 2017 Sep 14, Volume 209, p.248-254, (2017)

Can Randall's plug composed of calcium oxalate form via the free particle mechanism?, Grases, F, and Söhnel O , BMC Urol, 2017 Sep 08, Volume 17, Issue 1, p.80, (2017)

Time-dependent subcellular structure injuries induced by nano-/micron-sized calcium oxalate monohydrate and dihydrate crystals., Sun, Xin-Yuan, Yu Kai, and Ouyang Jian-Ming , Mater Sci Eng C Mater Biol Appl, 2017 Oct 01, Volume 79, p.445-456, (2017)

Invited response to Recurrence of oxalate nephropathy after isolated kidney transplantation for primary hyperoxaluria type 2., Dhondup, Tsering, Lorenz Elizabeth C., Milliner Dawn S., and Lieske John C. , Am J Transplant, 2017 Nov 21, (2017)

Inhibitory effect of an aqueous extract of Radix Paeoniae Alba on calcium oxalate nephrolithiasis in a rat model., Li, Xiaoran, Wang Wenyun, Su Yu, Yue Zhongjin, and Bao Junsheng , Ren Fail, 2017 Nov, Volume 39, Issue 1, p.120-129, (2017)

Calcium oxalate crystals induces tight junction disruption in distal renal tubular epithelial cells by activating ROS/Akt/p38 MAPK signaling pathway., Yu, Lei, Gan Xiuguo, Liu Xukun, and An Ruihua , Ren Fail, 2017 Nov, Volume 39, Issue 1, p.440-451, (2017)