A glucose biosensor based on novel Lutetium bis-phthalocyanine incorporated silica-polyaniline conducting nanobeads.

Title A glucose biosensor based on novel Lutetium bis-phthalocyanine incorporated silica-polyaniline conducting nanobeads.
Authors H. Al-Sagur; S. Komathi; H. Karaka?; D. Atilla; A.G. Gurek; T. Basova; N. Farmilo; A.K. Hassan
Journal Biosens Bioelectron
DOI 10.1016/j.bios.2017.12.004
Abstract

The facile preparation of highly sensitive electrochemical bioprobe based on lutetium phthalocyanine incorporated silica nanoparticles (SiO(LuPc)) grafted with Poly(vinyl alcohol-vinyl acetate) itaconic acid (PANI(PVIA)) doped polyaniline conducting nanobeads (SiO(LuPc)PANI(PVIA)-CNB) is reported. The preparation of CNB involves two stages (i) pristine synthesis of LuPc incorporated SiO and PANI(PVIA); (ii) covalent grafting of PANI(PVIA) onto the surface of SiO(LuPc). The morphology and other physico-chemical characteristics of CNB were investigated. The scanning electron microscopy images show that the average particle size of SiO(LuPc)PANI(PVIA)-CNB was between 180-220nm. The amperometric measurements showed that the fabricated SiO(LuPc)PANI(PVIA)-CNB/GOx biosensor exhibited wide linear range (1-16mM) detection of glucose with a low detection limit of 0.1mM. SiO(LuPc)PANI(PVIA)-CNB/GOx biosensor exhibited high sensitivity (38.53µAmMcm) towards the detection of glucose under optimized conditions. Besides, the real (juice and serum) sample analysis based on a standard addition method and direct detection method showed high precision for measuring glucose at SiO(LuPc)PANI(PVIA)-CNB/GOx biosensor. The SiO(LuPc)PANI(PVIA)-CNB/GOx biosensor stored under refrigerated condition over a period of 45 days retains ~ 96.4% glucose response current.

Citation H. Al-Sagur; S. Komathi; H. Karaka?; D. Atilla; A.G. Gurek; T. Basova; N. Farmilo; A.K. Hassan.A glucose biosensor based on novel Lutetium bis-phthalocyanine incorporated silica-polyaniline conducting nanobeads.. Biosens Bioelectron. 2018;102:637645. doi:10.1016/j.bios.2017.12.004

Related Elements

Lutetium

See more Lutetium products. Lutetium (atomic symbol: Lu, atomic number: 71) is a Block F, Group 3, Period 6 element with an atomic weight of 174.9668. The number of electrons in each of Lutetium's shells is [2, 8, 18, 32, 9, 2] and its electron configuration is [Xe] 4f15 5d1 6s2.Lutetium Bohr Model In its elemental form, lutetium has a silvery-white appearance. The lutetium atom has a radius of 174 pm and a Van der Waals radius of 221 pm. Lutetium was discovered and first isolated by Georges Urbain, Carl Auer von Welsbach and Charles James in 1906, all independently of each other.Elemental Lutetium Urbain was awarded the naming honor because he published his findings first. Lutetium is the last member of the rare earth series. Unlike most rare earths it lacks a magnetic moment. It has the smallest metallic radius of any rare earth and it is perhaps the least naturally abundant of the lanthanides. The most common source of commercially produced lutetium is the mineral monazite. The name lutetium originates from the Latin word Lutetia, meaning Paris. Lutetium is found with almost all other rare earth metals, but it never occurs naturally by itself.

Nitrogen

See more Nitrogen products. Nitrogen is a Block P, Group 15, Period 2 element. Its electron configuration is [He]2s22p3. Nitrogen is an odorless, tasteless, colorless and mostly inert gas. It is the seventh most abundant element in the universe and it constitutes 78.09% (by volume) of Earth's atmosphere. Nitrogen was discovered by Daniel Rutherford in 1772.

Silicon

See more Silicon products. Silicon (atomic symbol: Si, atomic number: 14) is a Block P, Group 14, Period 3 element with an atomic weight of 28.085. Silicon Bohr MoleculeThe number of electrons in each of Silicon's shells is 2, 8, 4 and its electron configuration is [Ne] 3s2 3p2. The silicon atom has a radius of 111 pm and a Van der Waals radius of 210 pm. Silicon was discovered and first isolated by Jöns Jacob Berzelius in 1823. Silicon makes up 25.7% of the earth's crust, by weight, and is the second most abundant element, exceeded only by oxygen. The metalloid is rarely found in pure crystal form and is usually produced from the iron-silicon alloy ferrosilicon. Elemental SiliconSilica (or silicon dioxide), as sand, is a principal ingredient of glass, one of the most inexpensive of materials with excellent mechanical, optical, thermal, and electrical properties. Ultra high purity silicon can be doped with boron, gallium, phosphorus, or arsenic to produce silicon for use in transistors, solar cells, rectifiers, and other solid-state devices which are used extensively in the electronics industry.The name Silicon originates from the Latin word silex which means flint or hard stone.

Related Forms & Applications