CAS #:

Linear Formula:


MDL Number:


EC No.:



>95% Bis(8-quinolinolato)copper(II)
Pricing > SDS > Data Sheet >

Bis(8-quinolinolato)copper(II) Properties (Theoretical)

Compound Formula C18H12CuN2O2
Molecular Weight 351.85
Appearance Yellow to deep green crystalline powder
Melting Point N/A
Boiling Point N/A
Density N/A
Solubility in H2O Insoluble
Exact Mass 351.019475 g/mol
Monoisotopic Mass 351.019475 g/mol

Bis(8-quinolinolato)copper(II) Health & Safety Information

Signal Word Warning
Hazard Statements N/A
Hazard Codes T, N
Risk Codes N/A
Safety Statements N/A
RTECS Number VC5250000
Transport Information N/A
GHS Pictograms

View and Print SDS


Date Accessed: 08/12/2022
Date Revised: 05/15/2015


Product Name: Bis(8-quinolinolato)copper(II)

Product Number: All applicable American Elements product codes, e.g. CU-OMX-015-C

CAS #: 10380-28-6

Relevant identified uses of the substance: Scientific research and development

Supplier details:
American Elements
10884 Weyburn Ave.
Los Angeles, CA 90024
Tel: +1 310-208-0551
Fax: +1 310-208-0351

Emergency telephone number:
Domestic, North America: +1 800-424-9300
International: +1 703-527-3887


OSHA Haz Com: CFR 1910.1200: Acute Toxicity - Oral [Category 4]
Eye Damage/Irritation [Category 2B]
Specific Target Organ Toxicity (Single Exposure) [Category 2]
Aquatic Hazard (Acute) [Category 1]
Signal word: Warning!
Hazard Statement(s): Causes eye irritation
Harmful if swallowed
Very toxic to aquatic life
May cause damage to organs:
Pictogram(s) or Symbol(s):

Exclamation Mark - GHS07Health Hazard - GHS08Environment - GHS09

Precautionary Statement(s):
[Prevention] Do not eat, drink or smoke when using this product. Wash hands and face thoroughly after handling. Do
not breathe dusts or mists. Wash all exposed skin thoroughly after handling.
[Response] If swallowed: Immediately call a poison center or doctor. Rinse mouth. If in eyes: Rinse cautiously with
water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye
irritation persists: Get medical advice or attention. If exposed or concerned: Call a poison center or doctor.
[Storage] Store locked up.
[Disposal] Dispose of contents and container in accordance with US EPA guidelines for the classification and
determination of hazardous waste listed in 40 CFR 261.3. (See Section 13)


Substance/Mixture: Substance
Components: Bis(8-quinolinolato)copper(II)
Percent: >95.0%(T)
CAS Number: 10380-28-6
Molecular Weight: 351.85
Chemical Formula: C18H12CuN2O2
Synonyms: Bis(8-hydroxyquinolinato)copper(II) , Copper(II) Bis(8-hydroxyquinolinate) , Oxine-Copper


Inhalation: Call emergency medical service. Effects of exposure (inhalation) to substance may be delayed. Inhalation
of vapors or contact with substance will result in contamination and potential harmful effects. Move victim
to fresh air. Give artificial respiration if victim is not breathing. Administer oxygen if breathing is difficult.
Keep victim warm and quiet. Treat symptomatically and supportively. Ensure that medical personnel are
aware of the material(s) involved and take precautions to protect themselves.
Skin contact: Call a poison center or doctor if you feel unwell. Effects of exposure (skin contact) to substance may be
delayed. Remove and wash contaminated clothing before re-use. Remove and isolate contaminated
clothing and shoes. In case of contact with substance, immediately flush skin with running water for at
least 20 minutes. Treat symptomatically and supportively. Ensure that medical personnel are aware of the
material(s) involved and take precautions to protect themselves.
Eye contact: IMMEDIATELY flush eyes with running water for at least 15 minutes, keeping eyelids open. Contact with
material may irritate or burn eyes. Call emergency medical service. Move victim to fresh air. Check for and
remove any contact lenses. Keep victim warm and quiet. Treat symptomatically and supportively. Effects of
exposure to substance may be delayed. Ensure that medical personnel are aware of the material(s)
involved and take precautions to protect themselves.
Ingestion: Harmful if swallowed. Do not induce vomiting with out medical advice. Effects of exposure (ingestion) to
substance may be delayed. If swallowed, seek medical advice immediately and show the container or
label. Do not use mouth-to-mouth method if victim ingested the substance; give artificial respiration with
the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Loosen tight clothing such as a collar, tie, belt or waistband. If a person vomits place them in the recovery
position so that vomit will not reenter the mouth and throat. Rinse mouth. Keep victim warm and quiet.
Treat symptomatically and supportively. Ensure that medical personnel are aware of the material(s)
involved and take precautions to protect themselves.
Acute: Redness.
Delayed: No data available
Immediate medical attention: WARNING: It might be hazardous to the person providing aid to give mouth-to-mouth respiration, because
the inhaled material is harmful. If breathing has stopped, perform artificial respiration. Use first aid
treatment according to the nature of the injury. Ensure that medical personnel are aware of the material(s)
involved and take precautions to protect themselves.


Suitable extinguishing media: Dry chemical, CO2 , water spray, or alcohol-resistant foam. Consult with local fire authorities before
attempting large scale fire fighting operations.
Specific hazards arising from the chemical
Hazardous combustion products: These products include: Carbon oxides Nitrogen oxides Metallic oxides
Other specific hazards: Closed containers may explode from heat of a fire.
Special precautions for fire-fighters:
Use water spray or fog; do not use straight streams. Dike fire-control water for later disposal; do not scatter the material. Containers may explode when
heated. Move containers from fire area if you can do it without risk.
Special protective equipment for fire-fighters:
Wear positive pressure self-contained breathing apparatus (SCBA). Structural fire fighters' protective clothing provides limited protection in fire situations
ONLY; it may not be effective in spill situations. Wear chemical protective clothing which is specifically recommended by the manufacturer. It may
provide little or no thermal protection.


Personal precautions: Avoid contact with skin, eyes, and clothing. Keep people away from and upwind of spill/leak. Do not touch
damaged containers or spilled material unless wearing appropriate protective clothing (Section 8). Warn
unnecessary personnel to move away. Stop leak if you can do it without risk. Ensure adequate ventilation.
Isolate the hazard area and deny entry to unnecessary and unprotected personnel.
Personal protective equipment: Wear eye protection (splash goggles) and face protection (full length face shield). Lab coat. Dust
respirator. Be sure to use a MSHA/NIOSH approved respirator or equivalent. Wear protective gloves
Emergency procedures: Prevent dust cloud. Do not clean-up or dispose except under supervision of a specialist. In case of a spill
and/or a leak, always shut off any sources of ignition, ventilate the area, and excercise caution. Do not
touch damaged containers or spilled material unless wearing appropriate protective clothing. Warn
personnel to move away. Prevent entry into sewers, basements or confined areas; dike if needed.
Methods and materials for containment and cleaning up:
ELIMINATE all ignition sources (no smoking, flares, sparks, or flames in immediate area). Stop leak if without risk. Absorb with an inert material and put
the spilled material in an appropriate waste disposal container. Use clean non-sparking tools to collect absorbed material. Dike far ahead of spill; use dry
sand to contain the flow of material. Ventilate the area.
Environmental precautions:
Keep away from living quarters. Environmental hazard. Do not let product enter drains. Prevent further leakage or spillage if safe to do so. Water runoff
can cause environmental damage. Prevent entry into sewers, basements or confined areas; dike if needed.


Precautions for safe handling: Avoid inhalation of vapor or mist. Do not ingest. Avoid contact with skin and eyes. Good general ventilation
should be sufficient to control airborne levels. Keep container dry. Handle and open container with care.
Wear suitable protective clothing, gloves and eye/face protection. When using do not eat, drink, or smoke.
Keep away from sources of ignition.
Conditions for safe storage: Store locked up. Keep containers tightly closed in a cool, well-ventilated place. Keep away from
incompatibles. Containers which are opened must be carefully resealed and kept upright to prevent
leakage. Avoid prolonged storage periods.
Storage incompatibilities: Store away from oxidizing agents


Exposure limits: No data available
Appropriate engineering controls:
Good general ventilation should be sufficient to control airborne levels. Ventilation is normally required when handling or using this product. Eyewash
fountains should be provided in areas where there is any possibility that workers could be exposed to the substance. Follow safe industrial
engineering/laboratory practices when handling any chemical.
Personal protective equipment
Respiratory protection: Dust respirator. Be sure to use a MSHA/NIOSH approved respirator or equivalent.
Hand protection: Wear protective gloves.
Eye protection: Safety glasses.
Skin and body protection: Lab coat.


Physical state (20°C): Solid
Form: Crystal - Powder
Color: Yellow - Deep green
Odor: Odorless
Odor threshold: No data available

Melting point/freezing point: No data available
Boiling point/range: No data available
Decomposition temperature: No data available
Relative density: No data available
Kinematic Viscosity: No data available
Partition coefficient: 2.46
n-octanol/water (log Pow)
Flash point: No data available
Flammability (solid, gas): No data available
pH: No data available
Vapor pressure: No data available
Vapor density: No data available
Dynamic Viscosity: No data available
Evaporation rate: No data available
(Butyl Acetate = 1)
Autoignition temperature: No data available
Flammability or explosive limits: No data available
Lower: No data available
Upper: No data available

Water: Insoluble (0.07mg/L)
Very slightly soluble: Chloroform, Hot pyridine
Insoluble: Many organic solvents


Reactivity: Not Available.
Chemical Stability: Stable under recommended storage conditions. (See Section 7)
Possibility of Hazardous Reactions: No hazardous reactivity has been reported.
Conditions to avoid: Avoid excessive heat and light.
Incompatible materials: Oxidizing agents
Hazardous Decomposition Products: No data available


RTECS Number: VC5250000
Acute Toxicity:
ihl-rat LC50:820 mg/kg
ipr-rat LD50:22 mg/kg
orl-rat LD50:9930 mg/kg
skn-rbt LD50:>2 g/kg
Skin corrosion/irritation:
No data available
Serious eye damage/irritation:
No data available
Respiratory or skin sensitization:
No data available
Germ cell mutagenicity:
mmo-sat 5 ug/plate (-S9)
scu-mus TDLo:156 mg/kg/39W-I
IARC: Group 3 (Not classifiable as
carcinogenic to humans).
NTP: No data available
OSHA: No data available
Reproductive toxicity:
No data available
Routes of Exposure: Inhalation, Eye contact, Ingestion, Skin contact.
Symptoms related to exposure:
Overexposure may result in serious illness or death. Eye contact may result in redness or pain.
Potential Health Effects:
No specific information available; skin and eye contact may result in irriatation. May be harmful if inhaled or ingested.
Target organ(s):
May cause damage to organs:


Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence and degradability: 64% (NO2), 76% (NH3) (by BOD), 97 % (by HPLC), 100 % (by UV-VIS)
Bioaccumulative potential (BCF): No data available
Mobillity in soil: No data available
Partition coefficient:
n-octanol/water (log Pow)
Soil adsorption (Koc): No data available
Henry's Law:
constant (PaM3/mol)
No data available


Disposal of product: Recycle to process if possible. It is the generator's responsibility to comply with Federal, State and Local
rules and regulations. You may be able to dissolve or mix material with a combustible solvent and burn in a
chemical incinerator equipped with an afterburner and scrubber system. This section is intended to provide
assistance but does not replace these laws, nor does compliance in accordance with this section ensure
regulatory compliance according to the law. US EPA guidelines for Identification and Listing of Hazardous
Waste are listed in 40 CFR Parts 261. The product should not be allowed to enter the environment, drains,
water ways, or the soil.
Disposal of container: Dispose of as unused product. Do not re-use empty containers.
Other considerations: Observe all federal, state and local regulations when disposing of the substance.


DOT (US) Non-hazardous for transportation.
IATA Non-hazardous for transportation.
IMDG Non-hazardous for transportation


Toxic Substance Control Act (TSCA 8b.):
This product is ON the EPA Toxic Substances Control Act (TSCA) inventory.
US Federal Regulations
CERCLA Hazardous substance and Reportable Quantity:
SARA 313: Not Listed
SARA 302: Not Listed
State Regulations
State Right-to-Know
Massachusetts Not Listed
New Jersey Not Listed
Pennsylvania Not Listed
California Proposition 65: Not Listed
Other Information
NFPA Rating:

HMIS Classification:

International Inventories
WHMIS hazard class: D2A: Materials causing other toxic effects. (Very Toxic)
D2B: Materials causing other toxic effects. (Toxic)
EC-No: 233-841-9


Safety Data Sheet according to Regulation (EC) No. 1907/2006 (REACH). The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. American Elements shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. COPYRIGHT 1997-2022 AMERICAN ELEMENTS. LICENSED GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY.

About Bis(8-quinolinolato)copper(II)

Bis(8-quinolinolato)copper(II) or Oxine-Copper is a copper-based organometallic compound used as a fungicide.

Bis(8-quinolinolato)copper(II) Synonyms

Copper(II) Bis(8-hydroxyquinolinate),Copper 8-quinolinolate; copper quinolate; oxine-copper; oxine-Cu; bis(quinolin-8-olato-O,N)copper(II); cupric 8-quinolinoxide; bis(8-quinolinolato-κN1,κO8)copper, Cu 8Q, copper oxinate, bioquin 1, copper dioxinate, copper oxyquinolate

Chemical Identifiers

Linear Formula C18H12CuN2O2
MDL Number MFCD00067392
EC No. 233-841-9
Pubchem CID 3032555
IUPAC Name copper; quinolin-8-olate
SMILES C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]
InchI Identifier InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2

Packaging Specifications

Typical bulk packaging includes palletized plastic 5 gallon/25 kg. pails, fiber and steel drums to 1 ton super sacks in full container (FCL) or truck load (T/L) quantities. Research and sample quantities and hygroscopic, oxidizing or other air sensitive materials may be packaged under argon or vacuum. Shipping documentation includes a Certificate of Analysis and Safety Data Sheet (SDS). Solutions are packaged in polypropylene, plastic or glass jars up to palletized 440 gallon liquid totes, and 36,000 lb. tanker trucks.

Related Elements


See more Copper products. Copper Bohr Model Copper (atomic symbol: Cu, atomic number: 29) is a Block D, Group 11, Period 4 element with an atomic weight of 63.546. The number of electrons in each of copper's shells is 2, 8, 18, 1 and its electron configuration is [Ar]3d10 4s1. The copper atom has a radius of 128 pm and a Van der Waals radius of 186 pm. Copper was first discovered by Early Man prior to 9000 BC. In its elemental form, copper has a reddish-orange metallic and lustrous appearance. Of all pure metals, only silver Elemental Copperhas a higher electrical conductivity. The origin of the word copper comes from the Latin word 'cuprium' which translates as "metal of Cyprus," as the Mediterranean island of Cyprus was known as an ancient source of mined copper..


August 12, 2022
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