High final energy of gallium arsenide laser increases MyoD gene expression during the intermediate phase of muscle regeneration after cryoinjury in rats.

Title High final energy of gallium arsenide laser increases MyoD gene expression during the intermediate phase of muscle regeneration after cryoinjury in rats.
Authors C.Pereira Santos; A.Fernando Aguiar; I.Cristina Giometti; T.Bruno Mariano; C.Eduardo As de Freitas; G.Alborghett Nai; S.Zambelli de Freitas; M. Dal Pai-Silva; F.Lopes Pacagnelli
Journal Lasers Med Sci
DOI 10.1007/s10103-018-2439-3
Abstract

The aim of this study was to determine the effects of gallium arsenide (GaAs) laser on IGF-I, MyoD, MAFbx, and TNF-? gene expression during the intermediate phase of muscle regeneration after cryoinjury 21 Wistar rats were divided into three groups (n?=?7 per group): untreated with no injury (control group), cryoinjury without GaAs (injured group), and cryoinjury with GaAs (GaAs-injured group). The cryoinjury was induced in the central region of the tibialis anterior muscle (TA). The region injured was irradiated once a day during 14 days using GaAs laser (904 nm; spot size 0.035 cm, output power 50 mW; energy density 69 J cm; exposure time 4 s per point; final energy 4.8 J). Twenty-four hours after the last application, the right and left TA muscles were collected for histological (collagen content) and molecular (gene expression of IGF-I, MyoD, MAFbx, and TNF-?) analyses, respectively. Data were analyzed using one-way ANOVA at P??0.05) differences in collagen density and IGF-I gene expression in all experimental groups. There were similar (P?

Citation C.Pereira Santos; A.Fernando Aguiar; I.Cristina Giometti; T.Bruno Mariano; C.Eduardo As de Freitas; G.Alborghett Nai; S.Zambelli de Freitas; M. Dal Pai-Silva; F.Lopes Pacagnelli.High final energy of gallium arsenide laser increases MyoD gene expression during the intermediate phase of muscle regeneration after cryoinjury in rats.. Lasers Med Sci. 2018;33(4):843850. doi:10.1007/s10103-018-2439-3

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Gallium

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