American Elements specializes in assisting our customers in the pharmaceutical industry in both R&D capacities and scaling up operations, allowing them to bring their products from "bench to clinic" in the most cost-efficient means possible. The American Elements pharmaceutical production facility in Bluffdale, Utah operates under fully documented GMP standards. It has been fully audited by Bristol Myers Squibb, Pfizer and many other important pharma customers.

Several key pharmaceutical, nutritional and cosmetic additives have been developed by or in cooperation with American Elements. For example, we co-developed a new class of excipient powder now in common use in such drugs as Abilify™.

Question? Speak to an American Elements engineer at pharmaceuticals@americanelements.com

Innovation Case Study #21: American Elements Invents New Rapid Dissolve Pharmaceutical Powder for Psychiatric Patients

#21: American Elements Invents New Rapid Dissolve Pharmaceutical Powder for Psychiatric Patients


The Challenge

Formulating new innovations in drugs often requires the development of two separate materials-the performing “Active Ingredient” and the “Excipient” which determines in which region(s) and how quickly the active ingredient will be absorbed in the patient’s body. Bristol Myers Squibb sought a new ultra quick dissolving powder that could easily pack into a pill using existing equipment for its new schizophrenia drug, Abilify™.

The Innovation

To meet this gap in excipient technology, American Elements invented a new class of micronized crystalline powder that both dissolved in the mouth instantly and exhibited excellent packing density. Once approved by BMS, we scaled the process to full scale production at our Murray, Utah facility.

The Result

Bristol Myers Squibb received FDA approval in 2002 for use of Abilify to treat schizophrenia. The drug is now in wide use. The excipient developed by American Elements can now be found in numerous other drugs as well. In 2012, American Elements transferred this technology to the Engineered Materials division of the JM Huber Corporation which markets the powder under the trade name RxCIPIENTS® FM1000.
Below is merely a selection of the full catalog of Pharmaceuticals & Cosmetics products that American Elements manufactures. If you do not see a material you're looking for listed, please search the website or contact customerservice@americanelements.com.

Selected Products Supplied to the Pharmaceuticals & Cosmetics Industry

(1R-trans)-1,2-Cyclohexanediamine Platinum Complex (4N) 99.99% High Purity Magnesium Oxide Powder (5N) 99.999% Silicon Oxide (6N) 99.9999% Selenium Metal
(6N) 99.9999% Ytterbium(III) Chloride Hexahydrate Aluminum Acetotartrate Aluminum Acrylate Ammonium Dihydrogen Arsenate
Ammonium Hexafluorogermanate Ammonium Iron(II) Sulfate Hexahydrate Ammonium Manganese(III) Pyrophosphate Boric Acid
Boron Citrate Bromo(triphenylphosphine)gold(I) Calcium Carbonate Calcium Carbonate Sputtering Target
Calcium Lactobionate Monohydrate Calcium Perchlorate Hydrate Calcium Phosphate Dibasic Anhydrous Calcium Phosphate Dibasic Dihydrate
Calcium-44 Carbonate Isotope Calcium-44 Chloride Isotope Calcium-44 Metal Isotope Carbonyl Iron Powder
Carboplatin Carboxylated Silver Nanoparticles Cesium Carbonate Cesium Carbonate Nanoparticles / Nanopowder
Chromium Phosphate Tetrahydrate cis-Diamminedichloroplatinum Copper Aluminum Zinc Alloy Cyclopentadienylrhenium Tricarbonyl
Devarda's Alloy Nanoparticles Disodium Calcium Ethylenediaminetetraacetate Disodium Calcium Ethylenediaminetetraacetate Hydrate Ferric Hydroxide Oxide
Foscarnet Sodium Salt Fumed Silica Gold Colloid Iron Blocks
Iron Cubes Iron Foil Iron(III) Chloride Iron(III) Oxide Powder
Lithium Carbonate Lithium Iodide Lithium Iodide Trihydrate Magnesium Aluminum Silicate
Magnesium Ammonium Phosphate Hexahydrate Magnesium Chromate Hydrate Magnesium Granules Magnesium Phosphate Tribasic Octahydrate
Mangafodipir Trisodium Manganese(II,III) Oxide Manganese(III) Oxide Manganese(III) Oxide Sputtering Target
Miboplatin Molybdenum Oxide Pellets Multi-Walled Carbon Nanotubes Nedaplatin
Neodymium Fluoride Nickel Tin Oxide Dihydrate Octamethylcyclotetrasiloxane Oxaliplatin
Platinum Oxide Powder Polyhydroxylated Fullerenes Potassium Bromide Potassium Bromide Windows
Potassium Carbonate Potassium Isopropoxide Raltegravir Potassium Salt Reduced Graphene Oxide
Samarium Oxide Powder Satraplatin Silicon Nanowire Dispersion Silicon Nanowires
Silver Carbonate Nanoparticles Sodium 2-mercaptoethanesulfonate Sodium Benzoate Sodium Dodecylbenzenesulfonate
Sodium Ferrocyanide Decahydrate Sodium Hydrogen Carbonate Sodium Nitrate Sodium Phosphate Dibasic Dihydrate
Sodium Phosphonoformate Tribasic Hexahydrate Sodium Salicylate Sodium Selenate Decahydrate Sodium Selenide
Sodium Stannate Sodium Stannate Trihydrate Spirogermanium Titanium Oxide Nanoparticle Dispersion
Titanium Oxide Nanoparticles / Nanopowder Titanium(IV) Oxide, Brookite Nanopowder trans-Diamminedichloroplatinum(II) Ytterbium Chloride
Ytterbium Fluoride Zinc Acetate Zinc Carbonate Zinc Carbonate Basic
Zinc Carbonate Sputtering Target Zinc Nanoparticle Dispersion Zinc Nanoparticles Zinc Oleate
Zinc Phosphate Dihydrate