A terbium(iii) luminescent ATCUN-based peptide sensor for selective and reversible detection of copper(ii) in biological media.

Author(s) Falcone, E.; Gonzalez, P.; Lorusso, L.; Sénèque, O.; Faller, P.; Raibaut, L.
Journal Chem Commun (Camb)
Date Published 2020 Mar 30
Abstract

The measurement of exchangeable Cu2+ levels in biological samples is gaining interest in the context of copper-related pathologies. Here, we report a Tb3+ luminescent turn-off sensor for Cu2+ based on the specific and suitable-affinity Xxx-Zzz-His (ATCUN) peptide motif, enabling Cu2+ detection in the presence of a biological fluorescent background.

DOI 10.1039/d0cc01007c
ISSN 1364-548X
Citation Falcone E, Gonzalez P, Lorusso L, Sénèque O, Faller P, Raibaut L. A terbium(iii) luminescent ATCUN-based peptide sensor for selective and reversible detection of copper(ii) in biological media. Chem Commun (Camb). 2020.