Cobalt oxyhydroxide nanoflakes with oxidase-mimicking activity induced chemiluminescence of luminol for glutathione detection.

Author(s) Yang, X.Ju; Li, R.Sheng; Li, C.Mei; Li, Y.Fang; Huang, C.Zhi
Journal Talanta
Date Published 2020 Aug 01

Cobalt oxyhydroxide nanoflakes (CoOOH NFs), a typical two-dimensional (2D) nanomaterials, were found to induce chemiluminescence (CL) of luminol since the oxidase-like activity of CoOOH NFs enables the dissolved oxygen to generate various radicals (OH, Oand O) even if without the addition of oxidants such as hydrogen peroxide, and these radicals could be scavenged by glutathione (GSH), making GSH could be detected sensitively in the range of 10 nM to 1 μM with the detection limit of 6.4 nM.

DOI 10.1016/j.talanta.2020.120928
ISSN 1873-3573
Citation Talanta. 2020;215:120928.

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