Comparative Heating Efficiency of Cobalt-, Manganese-, and Nickel-Ferrite Nanoparticles for a Hyperthermia Agent in Biomedicines.

Author(s) Dönmez, Ç.E.Demirci; Manna, P.K.; Nickel, R.; Aktürk, S.; van Lierop, J.
Journal ACS Appl Mater Interfaces
Date Published 2019 Feb 20

In this study, the ac magnetic hyperthermia responses of spinel CoFeO, MnFeO, and NiFeO nanoparticles of comparable sizes (∼20 nm) were investigated to evaluate their feasibility of use in magnetic hyperthermia. The heating ability of EDT-coated nanoparticles which were dispersed in two different carrier media, deionized water and ethylene glycol, at concentrations of 1 and 2 mg/mL, was evaluated by estimating the specific loss power (SLP) (which is a measure of magnetic energy transformed into heat) under magnetic fields of 15, 25, and 50 kA/m at a constant frequency of 195 kHz. The maximum value of SLP has been found to be ∼315 W/g for CoFeO and ∼295 W/g for MnFeO and NiFeO nanoparticles. We report very promising heating temperature rising characteristics of CoFeO, MnFeO, and NiFeO nanoparticles under different applied magnetic fields that indicate the effectiveness of these nanoparticles as hyperthermia agents.

DOI 10.1021/acsami.8b22600
ISSN 1944-8252
Citation ACS Appl Mater Interfaces. 2019;11(7):68586866.

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