Determination and removal of clenbuterol with a stable fluorescent zirconium(IV)-based metal organic framework.

Author(s) Yang, H.; Wang, B.; Cheng, J.; Wang, R.; Zhang, S.; Dong, S.; Wei, S.; Wang, P.; Li, J.R.
Journal Mikrochim Acta
Date Published 2019 Jun 14
Abstract

A metal organic framework (MOF) based adsorbent of type UiO-66 was hydrothermally prepared and applied to simultaneous sensing and removal of the asthma drug clenbuterol. The MOF possesses a large specific surface area (1460 cm·g) and a stable structure, and has a large adsorption capacity for clenbuterol (160 mg·g). If clenbuterol binds to the MOF, the fluorescence of the sorbent (best measured at excitation/emission wavelengths of 290/396 nm) is quenched by up to 88%. Based on these findings, a fluorometric assay has been developed for the rapid determination of clenbuterol. The adsorption equilibrium of UiO-66 for CLB can be achieved at 60 min and the adsorption efficiency is above 80%. The method has a linear response in the 4.0 to 40 ng·mL concentration range, and the lower limit of detection is 0.17 μM. All of this indicates that UiO-66 is promising for simultaneous detection and the removal of CLB in water. Graphical abstract Schematic presentation of the detection and removal of clenbuterol in water medium by a stable fluorescent Zr(IV)-based metal organic framework. This method exhibited a large adsorption capacity for clenbuterol (160 mg/g) and low limit of detection (0.17 μM).

DOI 10.1007/s00604-019-3586-3
ISSN 1436-5073
Citation Yang H, Wang B, Cheng J, Wang R, Zhang S, Dong S, et al. Determination and removal of clenbuterol with a stable fluorescent zirconium(IV)-based metal organic framework. Mikrochim Acta. 2019;186(7):454.

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