| Title | Effects of hemoglobin level on myocardial washout rate of thallium-201 in patients with normal myocardial perfusion assessed by single-photon emission computed tomography. |
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| Authors | Kurisu, S.; Sumimoto, Y.; Ikenaga, H.; Watanabe, N.; Ishibashi, K.; Dohi, Y.; Fukuda, Y.; Kihara, Y. |
| Journal | Heart Vessels |
| DOI | 10.1007/s00380-017-0975-6 |
| Abstract |
Myocardial perfusion single-photon emission computed tomography (SPECT) is often performed even in patients with suspected coronary artery disease complicated by anemia. We assessed the effects of hemoglobin level on myocardial washout rate of Thallium-201 (Tl-201) in patients with normal myocardial perfusion assessed by SPECT. The study population consisted of 231 patients with summed stress score of zero on SPECT. The mean myocardial washout rate of Tl-201 in the left ventricle was calculated from the stress and the redistribution Bull's eye map. Hematological test was performed within 2 weeks before gated SPECT. There were 135 male and 96 female patients with a mean age of 72.6 ± 9.0 years. The mean hemoglobin was 12.9 ± 1.9 mg/dl; the median was 13.2 mg/dl and the range was 8.0-16.5 mg/dl. There was a significant inverse correlation between hemoglobin level and myocardial washout rate of Tl-201 (r = -0.45, p 0.001). Univariate linear regression analysis showed that age, female, body mass index, serum creatinine, hemoglobin, end-diastolic volume, and ejection fraction were associated with myocardial washout rate of Tl-201. Multivariate analysis showed that only hemoglobin was the independent predictor of myocardial washout rate of Tl-201 (β = -0.35, p 0.001). Our data suggested that anemia was a major determinant of increased myocardial washout rate of Tl-201 in patients with normal myocardial perfusion on SPECT. |
See more Thallium products. Thallium (atomic symbol: Tl, atomic number: 81) is a Block P, Group 13, Period 6 element with an atomic weight of 204.38. 
The number of electrons in each of thallium's shells is 2, 8, 18, 32, 18, 3 and its electron configuration is [Xe] 4f14 5d10 6s2 6p1. The thallium atom has a radius of 170 pm and a Van der Waals radius of 196 pm. Thallium was discovered by Sir William Crookes in 1861 and first isolated by Claude-Auguste Lamy in 1862. Thallium is a post-transition metal that is not found free in nature. Thallium is primarily used for its electrical conductivity as thallium sulfide, which changes with exposure to infrared light. This ability makes the compound useful in photocells. 
Thallium bromide-iodide crystals have been used as infrared optical materials. Thallium has also been used with sulfur, selenium or arsenic to produce low melting glasses which become fluid between 125 and 150 °C, while thallium oxide has been used to produce glasses with a high index of refraction, and is also used in the manufacture of photo cells. Its name is derived from the Greek word thallos, which means twig or green shoot.