Hydroaminoalkylation of sterically hindered alkenes with N,N-dimethyl anilines using a scandium catalyst.

Author(s) Su, J.; Zhou, Y.; Xu, X.
Journal Org Biomol Chem
Date Published 2018 Dec 17
Abstract An atom- and step-economical C(sp3)-H addition of N,N-dimethyl anilines to various sterically demanding 1,1- and 1,2-disubstituted alkenes has been achieved by using a simple β-diketiminato ligand supported scandium dialkyl complex in combination with a borate compound. The corresponding C(sp3)-C(sp3) bond forming reaction occurs with excellent regioselectivities to give a variety of tertiary aromatic amines.
DOI 10.1039/c8ob02657b
ISSN 1477-0539
Citation Su J, Zhou Y, Xu X. Hydroaminoalkylation of sterically hindered alkenes with N,N-dimethyl anilines using a scandium catalyst. Org Biomol Chem. 2018.

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