One-Pot Synthesis of N-Imidoyl-(1H)-Indoles via Palladium-Catalyzed Oxidative Insertion Domino Reaction with Isocyanide and Arylboronic Acid.

Author(s) Tao, S.W.; Zhou, J.Y.; Liu, R.Q.; Zhu, Y.M.
Journal J Org Chem
Date Published 2019 May 27
Abstract

An efficient one-pot synthesis of N-imidoyl-(1H)-indoles has been described, which is achieved by the palladium-catalyzed oxidative insertion of 2-(phenylethynyl)aniline, arylboronic acid and isonitrile. This method provide a new way to synthesize N-imidoyl-(1H)-indoles which has a wide substrate scope, good functional group tolerance and mild reaction condition.

DOI 10.1021/acs.joc.9b00990
ISSN 1520-6904
Citation Tao S-, Zhou J-, Liu R-, Zhu Y-. One-Pot Synthesis of N-Imidoyl-(1H)-Indoles via Palladium-Catalyzed Oxidative Insertion Domino Reaction with Isocyanide and Arylboronic Acid. J Org Chem. 2019.