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[Progress in treatment of acute aluminum phosphide poisoning].

Author(s) Lu, M.F.; Nie, S.N.
Journal Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
Date Published 2019 Nov 20
Abstract

Aluminum phosphide (ALP) is frequently used for grain conservation despite its high toxicity. In some developing countries increased utilization of ALP has resulted in increment of ALP-attributed poisoning numbers. The mortality of ALP poisoning is extremely high and no effective antidote is available so far. However, the astute survey of potential misconceptions in the course of acute toxicity has led some scientists to introduce novel therapeutic approaches. Meanwhile, some new antioxidants were discovered and expected to be used in the management of ALP poisoning. In addition, the progress in intensive care has promoted technologies such as CRRT, IABP and ECMO for the treatment of ALP poisoning with reported success in alleviating severe toxicity. Recent studies on the therapy of ALP poisoning are reviewed in this article.

DOI 10.3760/cma.j.issn.1001-9391.2019.11.021
Keywords Aluminum Compounds; Antioxidants; Humans; Pesticides; Phosphines; Poisoning
ISSN 1001-9391
Citation Lu MF, Nie SN. [Progress in treatment of acute aluminum phosphide poisoning]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2019;37(11):877-880.

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