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Reversible and Sensitive HgDetection by a Cell-Permeable Ytterbium Complex.
Title Reversible and Sensitive HgDetection by a Cell-Permeable Ytterbium Complex.
Authors Bao, G.; Zha, S.; Liu, Z.; Fung, Y.H.; Chan, C.F.; Li, H.; Chu, P.H.; Jin, D.; Tanner, P.A.; Wong, K.L.
Journal Inorg Chem
DOI 10.1021/acs.inorgchem.7b02243
Abstract

A cell-permeable ytterbium complex shows reversible binding with Hgin aqueous solution and in vitroby off-on visible and NIR emission. The fast response and 150 nM sensitivity of Hgdetection is based upon FRET and the lanthanide antenna effect. The reversible Hgdetection can be performed in vitro, and the binding mechanism is suggested by NMR employing the motif structure in a La complex and by DFT calculations.