Sequential Pd2(dba)3 participated C–C bond cleavage of O-bromophenyl cyclobutanones/Michael addition en route to benzospirones

Title Sequential Pd2(dba)3 participated C–C bond cleavage of O-bromophenyl cyclobutanones/Michael addition en route to benzospirones
Authors Fu, L.; Wu, Y.; Pei, W.; Ao, Y.; Zhang, L.; Zhang, Z.; Zhang, M.; Liu, Y.
Journal Journal of Saudi Chemical Society
DOI 10.1016/j.jscs.2018.03.003
Abstract A tandem Pd2(dba)3 participated C–C bond cleavage of O-bromophenyl cyclobutanone derivatives/Michael addition reaction sequence was realized. We disclosed the first intramolecular C–Br bond triggered ring opening reaction of arylcyclobutanones, distinct from related reports in which the reactions were initiated by arylboron, silane or unsaturated chemical motifs, among others. The in situ generated palladium species underwent ring expansion process leading to methyleneindanones, which further reacted with dba to provide benzospirones in one step.
Citation Fu, L.; Wu, Y.; Pei, W.; Ao, Y.; Zhang, L.; Zhang, Z.; Zhang, M.; Liu, Y..Sequential Pd2(dba)3 participated C–C bond cleavage of O-bromophenyl cyclobutanones/Michael addition en route to benzospirones.

Related Elements

Palladium

46 Pd 106.420000000 Palladium

Palladium Bohr ModelSee more Palladium products. Palladium (atomic symbol: Pd, atomic number: 46) is a Block D, Group 10, Period 5 element with an atomic weight of 106.42. The number of electrons in each of palladium's shells is 2, 8, 18, 18 and its electron configuration is [Kr] 4d10. The palladium atom has a radius of 137 pm and a Van der Waals radius of 202 pm. In its elemental form, palladium has a silvery white appearance. Palladium is a member of the platinum group of metals (along with platinum, rhodium, ruthenium, iridium and osmium). Elemental PalladiumPalladium has the lowest melting point and is the least dense of the group. Palladium can be found as a free metal and alloyed with other platinum-group metals. Nickel-copper deposits are the main commercial source of palladium. Palladium was discovered and first isolated by William Hyde Wollaston in 1803. Its name is derived from the asteroid Pallas.

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