Synthesis of Nano-Praseodymium Oxide for Cataluminescence Sensing of Acetophenone in Exhaled Breath.

Author(s) Zhang, Q.C.; Yan, W.L.; Jiang, L.; Zheng, Y.G.; Wang, J.X.; Zhang, R.K.
Journal Molecules
Date Published 2019 Nov 23
Abstract

In this work, we successfully developed a novel and sensitive gas sensor for the determination of trace acetophenone based on its cataluminescence (CTL) emission on the surface of nano-praseodymium oxide (nano-PrO). The effects of working conditions such as temperature, flow rate, and detecting wavelength on the CTL sensing were investigated in detail. Under the optimized conditions, the sensor exhibited linear response to the acetophenone in the range of 15-280 mg/m (2.8-52 ppm), with a correlation coefficient () of 0.9968 and a limit of detection (S/N = 3) of 4 mg/m (0.7 ppm). The selectivity of the sensor was also investigated, no or weak response to other compounds, such as alcohols (methanol, ethanol, -propanol, -propanol, -butanol), aldehyde (formaldehyde and acetaldehyde), benzenes (toluene, -xylene, -xylene, -xylene), -pentane, ethyl acetate, ammonia, carbon monoxide, carbon dioxide. Finally, the present sensor was applied to the determination of acetophenone in human exhaled breath samples. The results showed that the sensor has promising application in clinical breath analysis.

DOI 10.3390/molecules24234275
Keywords Acetophenones; Biosensing Techniques; Breast Neoplasms; Breath Tests; Catalysis; Female; Humans; Luminescence; Nanoparticles; Oxides; Praseodymium; Surface Properties
ISSN 1420-3049
Citation Zhang Q-, Yan W-, Jiang L, Zheng Y-, Wang J-, Zhang R-. Synthesis of Nano-Praseodymium Oxide for Cataluminescence Sensing of Acetophenone in Exhaled Breath. Molecules. 2019;24(23).