Rhodium-Catalyzed ?-Selective Oxidative Heck-Type Coupling of Vinyl Acetate via C-H Activation.

Title Rhodium-Catalyzed ?-Selective Oxidative Heck-Type Coupling of Vinyl Acetate via C-H Activation.
Authors H.J. Zhang; W. Lin; F. Su; T. Bin Wen
Journal Org Lett
DOI 10.1021/acs.orglett.6b03244
Abstract

An efficient Rh(III)-catalyzed direct ortho-C-H olefination of acetanilides with vinyl acetate was developed. This protocol provides a straightforward pathway to a series of (E)-2-acetamidostyryl acetates, giving access to indole derivatives following a simple hydrolysis/cyclization process.

Citation H.J. Zhang; W. Lin; F. Su; T. Bin Wen.Rhodium-Catalyzed ?-Selective Oxidative Heck-Type Coupling of Vinyl Acetate via C-H Activation.. Org Lett. 2016;18(24):63566359. doi:10.1021/acs.orglett.6b03244

Related Elements

Rhodium

See more Rhodium products. Rhodium (atomic symbol: Rh, atomic number: 45) is a Block D, Group 9, Period 5 element with an atomic weight of 102.90550. Rhodium Bohr ModelThe number of electrons in each of Rhodium's shells is [2, 8, 18, 16, 1] and its electron configuration is [Kr] 4d8 5s1. The rhodium atom has a radius of 134 pm and a Van der Waals radius of 195 pm. Rhodium was discovered and first isolated by William Wollaston in 1804. In its elemental form, rhodium has a silvery white metallic appearance. Elemental RhodiumRhodium is a member of the platinum group of metals. It has a higher melting point than platinum, but a lower density. Rhodium is found in ores mixed with other metals such as palladium, silver, platinum, and gold. Rhodium is primarily used as the catalyst in the three-way catalytic converters of automobiles it is also highly valued in jewelry. The name Rhodium originates from the Greek word 'Rhodon,' which means rose.

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