20th anniversary seal20th anniversary seal20th anniversary seal

Strontium Ranelate

CAS #:

Linear Formula:

C12H6N2O8SSr2

MDL Number:

MFCD09038742

EC No.:

N/A

ORDER

PRODUCT Product Code ORDER SAFETY DATA TECHNICAL DATA
Strontium Ranelate
SR-OMX-01
Pricing > SDS > Data Sheet >

Properties

Compound Formula

C12H6N2O8SSr2

Molecular Weight

342.283

Appearance

Solid

Melting Point

N/A

Boiling Point

778.8°C

Density

N/A

Exact Mass

513.79571

Monoisotopic Mass

513.79571

Health & Safety Information

Signal Word N/A
Hazard Statements N/A
Hazard Codes N/A
Risk Codes N/A
Safety Statements N/A
Transport Information N/A

View and Print SDS

SAFETY DATA SHEET

Date Accessed: 04/24/2017
Date Revised: 05/15/2015

SECTION 1. IDENTIFICATION

Product Name: Strontium Ranelate

Product Number: All applicable American Elements product codes, e.g. SR-OMX-01

CAS #: 135459-87-9

Relevant identified uses of the substance: Scientific research and development

Supplier details:
American Elements
1093 Broxton Ave. Suite 2000
Los Angeles, CA 90024
Tel: +1 310-208-0551
Fax: +1 310-208-0351

Emergency telephone number:
Domestic, North America +1 800-424-9300
International +1 703-527-3887


SECTION 2. HAZARDS IDENTIFICATION

OSHA Haz Com: CFR 1910.1200: Acute Toxicity - Oral [Category 4]
Acute Toxicity - Dermal [Category 4]
Acute Toxicity - Inhalation [Category 4]
Skin Corrosion/Irritation [Category 2]
Eye Damage/Irritation [Category 2A]
Signal word: Warning!
Hazard Statement(s): Causes serious eye irritation
Causes skin irritation
Harmful if swallowed
Harmful in contact with skin
Harmful if inhaled

Exclamation Mark - GHS07

Pictogram(s) or Symbol(s):
Precautionary Statement(s):
[Prevention] Do not eat, drink or smoke when using this product. Wash hands and face thoroughly after handling. Wear
protective gloves and protective clothing. Avoid breathing dusts or mists. Use only outdoors or in a wellventilated
area. Wear protective gloves. Wear eye and face protection.
[Response] If swallowed: Immediately call a poison center or doctor. Rinse mouth. If on skin: Wash with plenty of
water. Call a poison center or doctor if you feel unwell. Take off contaminated clothing and wash it before
reuse. If inhaled: Remove person to fresh air and keep comfortable for breathing. If skin irritation or rash
occurs: Get medical advice/attention. If in eyes: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or
attention.
[Storage] None
[Disposal] Dispose of contents and container in accordance with US EPA guidelines for the classification and
determination of hazardous waste listed in 40 CFR 261.3. (See Section 13)
Supplementary Information: While this material is not classified as hazardous under OSHA, this SDS contains valuable information
critical to safe handling and proper use of the product. This SDS should be retained and available for
employees and other users of this product.


SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS

Substance/Mixture: Substance
Components: Strontium Ranelate
Percent: >97.0%(T)
CAS Number: 135459-87-9
Molecular Weight: 513.49
Chemical Formula: C12H6N2O8SSr2
Synonyms: Ranelic Acid Strontium Salt


SECTION 4. FIRST AID MEASURES

Inhalation: Call a poison center or doctor if you feel unwell. Move victim to fresh air. Give artificial respiration if victim
is not breathing. Administer oxygen if breathing is difficult. Keep victim warm and quiet. Treat
symptomatically and supportively. Ensure that medical personnel are aware of the material(s) involved and
take precautions to protect themselves.
Skin contact: Call a poison center or doctor if you feel unwell. Remove and wash contaminated clothing before re-use.
Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately
flush skin with running water for at least 20 minutes. Treat symptomatically and supportively. Ensure that
medical personnel are aware of the material(s) involved and take precautions to protect themselves.
Eye contact: IMMEDIATELY flush eyes with running water for at least 15 minutes, keeping eyelids open. Contact with
material may irritate or burn eyes. Call emergency medical service. Move victim to fresh air. Check for and
remove any contact lenses. Keep victim warm and quiet. Treat symptomatically and supportively. Effects of
exposure to substance may be delayed. Ensure that medical personnel are aware of the material(s)
involved and take precautions to protect themselves.
Ingestion: Harmful if swallowed. Do not induce vomiting with out medical advice. Call a physician or Poison Control
Center immediately. Do not use mouth-to-mouth method if victim ingested the substance; give artificial
respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory
medical device. Loosen tight clothing such as a collar, tie, belt or waistband. If a person vomits place them
in the recovery position so that vomit will not reenter the mouth and throat. Rinse mouth. Keep victim warm
and quiet. Treat symptomatically and supportively. Ensure that medical personnel are aware of the
material(s) involved and take precautions to protect themselves.
Symptoms/effects:
Acute: No data available
Delayed: No data available
Immediate medical attention: WARNING: It might be hazardous to the person providing aid to give mouth-to-mouth respiration, because
the inhaled material is harmful. If breathing has stopped, perform artificial respiration. Use first aid
treatment according to the nature of the injury. Ensure that medical personnel are aware of the material(s)
involved and take precautions to protect themselves.


SECTION 5. FIREFIGHTING MEASURES

Suitable extinguishing media: Dry chemical, CO2 , sand, earth, water spray or regular foam Consult with local fire authorities before
attempting large scale fire fighting operations.
Specific hazards arising from the chemical
Hazardous combustion products: None
Other specific hazards: Closed containers may explode from heat of a fire.
Special precautions for fire-fighters:
Use water spray or fog; do not use straight streams. Dike fire-control water for later disposal; do not scatter the material. Containers may explode when
heated. Move containers from fire area if you can do it without risk.
Special protective equipment for fire-fighters:
Wear positive pressure self-contained breathing apparatus (SCBA). Structural fire fighters' protective clothing provides limited protection in fire situations
ONLY; it may not be effective in spill situations. Wear chemical protective clothing which is specifically recommended by the manufacturer. It may
provide little or no thermal protection.


SECTION 6. ACCIDENTAL RELEASE MEASURES

Personal precautions: Avoid contact with skin, eyes, and clothing. Keep people away from and upwind of spill/leak. Do not touch
damaged containers or spilled material unless wearing appropriate protective clothing (Section 8). Warn
unnecessary personnel to move away. Stop leak if you can do it without risk. Ensure adequate ventilation.
Isolate the hazard area and deny entry to unnecessary and unprotected personnel.
Personal protective equipment: Wear eye protection (splash goggles) and face protection (full length face shield). Lab coat. Dust
respirator. Be sure to use a MSHA/NIOSH approved respirator or equivalent. Wear protective gloves
(nitrile).
Emergency procedures: Prevent dust cloud. In case of a spill and/or a leak, always shut off any sources of ignition, ventilate the
area, and excercise caution. Do not touch damaged containers or spilled material unless wearing
appropriate protective clothing. Warn personnel to move away. Prevent entry into sewers, basements or
confined areas; dike if needed.
Methods and materials for containment and cleaning up:
ELIMINATE all ignition sources (no smoking, flares, sparks, or flames in immediate area). Stop leak if without risk. Ventilate the area. Absorb with an
inert material and put the spilled material in an appropriate waste disposal container. Use clean non-sparking tools to collect absorbed material.
Environmental precautions:
Keep away from living quarters. Prevent further leakage or spillage if safe to do so. Water runoff can cause environmental damage. Prevent entry into
sewers, basements or confined areas; dike if needed.


SECTION 7. HANDLING AND STORAGE

Precautions for safe handling: Avoid inhalation of vapor or mist. Do not ingest. Avoid contact with skin and eyes. Avoid contact with skin.
Good general ventilation should be sufficient to control airborne levels. Keep container dry. Handle and
open container with care. Wear suitable protective clothing, gloves and eye/face protection. When using do
not eat, drink, or smoke. Keep away from sources of ignition.
Conditions for safe storage: Keep only in the original container in a cool well-ventilated place. Keep away from incompatibles.
Containers which are opened must be carefully resealed and kept upright to prevent leakage. Avoid
prolonged storage periods. Store in a freezer.
Storage incompatibilities: Store away from oxidizing agents


SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Exposure limits: No data available
Appropriate engineering controls:
Good general ventilation should be sufficient to control airborne levels. Ventilation is normally required when handling or using this product. Eyewash
fountains should be provided in areas where there is any possibility that workers could be exposed to the substance. Follow safe industrial
engineering/laboratory practices when handling any chemical.
Personal protective equipment
Respiratory protection: Dust respirator. Be sure to use a MSHA/NIOSH approved respirator or equivalent.
Hand protection: Nitrile gloves.
Eye protection: Safety glasses.
Skin and body protection: Lab coat.


SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES

Physical state (20°C): Solid
Form: Crystal - Powder
Color: White - Slightly pale yellow
Odor: No data available
Odor threshold: No data available

Melting point/freezing point: No data available
Boiling point/range: No data available
Decomposition temperature: No data available
Relative density: No data available
Kinematic Viscosity: No data available
Partition coefficient: No data available
n-octanol/water (log Pow)
Flash point: No data available
Flammability (solid, gas): No data available

pH: No data available
Vapor pressure: No data available
Vapor density: No data available
Dynamic Viscosity: No data available
Evaporation rate: No data available
(Butyl Acetate = 1)
Autoignition temperature: No data available
Flammability or explosive limits: No data available
Lower: No data available
Upper: No data available

Solubility(ies):
Water: Insoluble
Insoluble: Ether, Benzene, Ethanol


SECTION 10. STABILITY AND REACTIVITY

Reactivity: Not Available.
Chemical Stability: Stable under recommended storage conditions. (See Section 7)
Possibility of Hazardous Reactions: No hazardous reactivity has been reported.
Conditions to avoid: Avoid excessive heat and light.
Incompatible materials: Oxidizing agents
Hazardous Decomposition Products: No data available


SECTION 11. TOXICOLOGICAL INFORMATION

Acute Toxicity:
No data available
Skin corrosion/irritation:
No data available
Serious eye damage/irritation:
No data available
Respiratory or skin sensitization:
No data available
Germ cell mutagenicity:
No data available
Carcinogenicity:
No data available
IARC: No data available
NTP: No data available
OSHA: No data available
Reproductive toxicity:
No data available
Routes of Exposure: Inhalation, Eye contact, Ingestion, Skin contact.
Symptoms related to exposure:
Overexposure may result in serious illness or death. Skin contact may result in inflammation; characterized by itching, scaling, reddening, or occasionally
blistering. Skin contact may result in redness, pain or dry skin. Eye contact may result in redness or pain.
Potential Health Effects:
Skin and eye contact may result in irritation.
Target organ(s): No data available


SECTION 12. ECOLOGICAL INFORMATION

Ecotoxicity
Fish: No data available
Crustacea: No data available
Algae: No data available
Persistence and degradability: No data available
Bioaccumulative potential (BCF): No data available
Mobillity in soil: No data available
Partition coefficient:
n-octanol/water (log Pow)
No data available
Soil adsorption (Koc): No data available
Henry's Law:
constant (PaM3/mol)
No data available


SECTION 13. DISPOSAL CONSIDERATIONS

Disposal of product: Recycle to process if possible. It is the generator's responsibility to comply with Federal, State and Local
rules and regulations. You may be able to dissolve or mix material with a combustible solvent and burn in a
chemical incinerator equipped with an afterburner and scrubber system. This section is intended to provide
assistance but does not replace these laws, nor does compliance in accordance with this section ensure
regulatory compliance according to the law. US EPA guidelines for Identification and Listing of Hazardous
Waste are listed in 40 CFR Parts 261. The product should not be allowed to enter the environment, drains,
water ways, or the soil.
Disposal of container: Dispose of as unused product. Do not re-use empty containers.
Other considerations: Observe all federal, state and local regulations when disposing of the substance.


SECTION 14. TRANSPORT INFORMATION

DOT (US) Non-hazardous for transportation.
IATA Non-hazardous for transportation.
IMDG Non-hazardous for transportation.


SECTION 15. REGULATORY INFORMATION

Toxic Substance Control Act (TSCA 8b.):
This product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40 CFR 720.36 (C) for those
products not on the inventory list:
(i) These products are supplied solely for use in research and development by or under the supervision of a technically qualified individual as defined in
40 CFR 720.0 et sec.
(ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be supplied on a SDS sheet.
US Federal Regulations
CERCLA Hazardous substance and Reportable Quantity:
SARA 313: Not Listed
SARA 302: Not Listed
State Regulations
State Right-to-Know
Massachusetts Not Listed
New Jersey Not Listed
Pennsylvania Not Listed
California Proposition 65: Not Listed
Other Information
NFPA Rating:
Health: 0
Flammability: 0
Instability: 0
HMIS Classification:
Health: 0
Flammability: 0
Physical: 0
International Inventories


16. OTHER INFORMATION

Safety Data Sheet according to Regulation (EC) No. 1907/2006 (REACH). The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. American Elements shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. COPYRIGHT 1997-2016 AMERICAN ELEMENTS. LICENSED GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY.

About

Strontium Ranelate is generally immediately available in most volumes, including bulk quantities. American Elements can produce most materials in high purity and ultra high purity (up to 99.99999%) forms and follows applicable ASTM testing standards; a range of grades are available including Mil Spec (military grade), ACS, Reagent and Technical Grade, Food, Agricultural and Pharmaceutical Grade, Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia). We can also produce materials to custom specifications by request, in addition to custom compositions for commercial and research applications and new proprietary technologies. Typical and custom packaging is available, as is additional research, technical and safety (MSDS) data. Please contact us above for information on specifications, lead time and pricing.

Synonyms

Ranelic acid, strontium salt; 5-(Bis(carboxymethyl)amino)-2-carboxy-4-cyano-3-thiopheneacetic acid; 3-Thiopheneacetic acid, 5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-, strontium salt (1:2), 135459-90-4, 2-[N,N-Di(carboxymethyl)amino]-3-cyano-4-carboxymethylthiophene-5-carboxylic acid strontium salt, 5-[Bis(carboxymethyl)amino]-2-carboxy-4-cyano-3-thiopheneacetic acid, strontium salt, Distrontium renelate, Ranelic acid strontium salt

Chemical Identifiers

Linear Formula

C12H6N2O8SSr2

Pubchem CID

46782942

MDL Number

MFCD09038742

EC No.

N/A

Beilstein Registry No.

N/A

IUPAC Name

distrontium; 5-[bis(carboxylatomethyl)amino]-3-(carboxylatomethyl)-4-cyanothiophene-2-carboxylate

SMILES

InChI=1S/C12H10N2O8S.2Sr/c13-2-6-5(1-7(15)16)10(12(21)22)23-11(6)14(3-8(17)18)4-9(19)20;;/h1,3-4H2,(H,15,16)(H,17,18)(H,19,20)(H,21,22);;/q;2*+2/p-4

InchI Identifier

C(C1=C(SC(=C1C#N)N(CC(=O)[O-])CC(=O)[O-])C(=O)[O-])C(=O)[O-].[Sr+2].[Sr+2]

InchI Key

XXUZFRDUEGQHOV-UHFFFAOYSA-J

Packaging Specifications

Typical bulk packaging includes palletized plastic 5 gallon/25 kg. pails, fiber and steel drums to 1 ton super sacks in full container (FCL) or truck load (T/L) quantities. Research and sample quantities and hygroscopic, oxidizing or other air sensitive materials may be packaged under argon or vacuum. Shipping documentation includes a Certificate of Analysis and Safety Data Sheet (SDS). Solutions are packaged in polypropylene, plastic or glass jars up to palletized 440 gallon liquid totes, and 36,000 lb. tanker trucks.

Related Elements

See more Strontium products. Strontium (atomic symbol: Sr, atomic number: 38) is a Block S, Group 2, Period 5 element with an atomic weight of 87.62 . Strontium Bohr ModelThe number of electrons in each of Strontium's shells is [2, 8, 18, 8, 2] and its electron configuration is [Kr] 5s2. The strontium atom has a radius of 215 pm and a Van der Waals radius of 249 pm. Strontium was discovered by William Cruickshank in 1787 and first isolated by Humphry Davy in 1808. In its elemental form, strontium is a soft, silvery white metallic solid that quickly turns yellow when exposed to air. Elemental StrontiumCathode ray tubes in televisions are made of strontium, which are becoming increasingly displaced by other display technologies pyrotechnics and fireworks employ strontium salts to achhieve a bright red color. Radioactive isotopes of strontium have been used in radioisotope thermoelectric generators (RTGs) and for certain cancer treatments. In nature, most strontium is found in celestite (as strontium sulfate) and strontianite (as strontium carbonate). Strontium was named after the Scottish town where it was discovered.

Recent Research

Tunable resistance switching in solution processed chromium-doped strontium titanate nanoparticles films., Wan, Tao, Qu Bo, Du Haiwei, Lin Xi, Guan Peiyuan, Lin Qianru, Chen Nan, Tan Thiam Teck, Hang Tao, and Chu Dewei , J Colloid Interface Sci, 2017 May 15, Volume 494, p.178-184, (2017)

Tunable pyroelectric properties of barium strontium titanate thin films., Shirokov, V B., Razumnaya A G., and Yuzyuk Yu I. , J Phys Condens Matter, 2017 May 10, Volume 29, Issue 18, p.185701, (2017)

Nucleation and growth process of atomic layer deposition platinum nanoparticles on strontium titanate nanocuboids., Wang, Chuandao, Hu Linhua, Poeppelmeier Kenneth, Stair Peter C., and Marks Laurence , Nanotechnology, 2017 May 05, Volume 28, Issue 18, p.185704, (2017)

Effect of strontium on Nd doped Ba1-x Sr x Ce0.65Zr0.25Nd0.1O3-δ proton conductor as an electrolyte for solid oxide fuel cells., J Sailaja, Madhuri, K Babu Vijaya, Murali N, and Veeraiah V , J Adv Res, 2017 May, Volume 8, Issue 3, p.169-181, (2017)

Orange-red emitting europium doped strontium ortho-silicate phosphor prepared by a solid state reaction method., Sahu, Ishwar Prasad , Luminescence, 2017 May, Volume 32, Issue 3, p.364-374, (2017)

Preferential site occupancy of Eu(3+) ions in strontium hydroxyapatite nanocrystalline - Sr10(PO4)6(OH)2 - structural and spectroscopic characterisation., Zawisza, Katarzyna, and Wiglusz Rafal J. , Dalton Trans, 2017 Mar 07, Volume 46, Issue 10, p.3265-3275, (2017)

Formation, Structure, and Frequency-Doubling Effect of a Modification of Strontium Cyanurate (α-SCY)., Kalmutzki, Markus Johannes, Dolabdjian Konstantin, Wichtner Nadja, Ströbele Markus, Berthold Christoph, and Meyer Hans-Jürgen , Inorg Chem, 2017 Mar 07, (2017)

Role of magnesium oxide and strontium oxide as modifiers in silicate-based bioactive glasses: Effects on thermal behaviour, mechanical properties and in-vitro bioactivity., Bellucci, Devis, Sola Antonella, Salvatori Roberta, Anesi Alexandre, Chiarini Luigi, and Cannillo Valeria , Mater Sci Eng C Mater Biol Appl, 2017 Mar 01, Volume 72, p.566-575, (2017)

Strontium hydroxyapatite/chitosan nanohybrid scaffolds with enhanced osteoinductivity for bone tissue engineering., Lei, Yong, Xu Zhengliang, Ke Qinfei, Yin Wenjing, Chen Yixuan, Zhang Changqing, and Guo Yaping , Mater Sci Eng C Mater Biol Appl, 2017 Mar 01, Volume 72, p.134-142, (2017)

Configuration interaction study on the low-lying electronic states of strontium hydride cation including spin-orbit coupling., Shi, Dandan, Liu Xiaoting, Shan Shimin, Xu Haifeng, and Yan Bing , Spectrochim Acta A Mol Biomol Spectrosc, 2017 Jun 05, Volume 180, p.29-36, (2017)

TODAY'S SCIENCE POST!

April 24, 2017
Los Angeles, CA
Each business day American Elements' scientists & engineers post their choice for the most exciting materials science news of the day

3-D printing glass objects