Tetramethyl Orthosilicate

SECTION 1. IDENTIFICATION

Product Name: Tetramethyl Orthosilicate

Product Number: All applicable American Elements product codes, e.g. 4MTH-OSAT-02-LIQ , 4MTH-OSAT-03-LIQ , 4MTH-OSAT-04-LIQ , 4MTH-OSAT-05-LIQ , 4MTH-OSAT-018-LIQ

CAS #: 681-84-5

Relevant identified uses of the substance: Scientific research and development

Supplier details:
American Elements
10884 Weyburn Ave.
Los Angeles, CA 90024
Tel: +1 310-208-0551
Fax: +1 310-208-0351

Emergency telephone number:
Domestic, North America: +1 800-424-9300
International: +1 703-527-3887

SECTION 2. HAZARDS IDENTIFICATION

Classification of the substance or mixture in accordance with 29 CFR 1910 (OSHA HCS)
GHS02 Flame
Flam. Liq. 3 H226 Flammable liquid and vapour.
GHS06 Skull and crossbones
Acute Tox. 1 H330 Fatal if inhaled.
GHS05 Corrosion
Eye Dam. 1 H318 Causes serious eye damage.
GHS07
Skin Irrit. 2
H315 Causes skin irritation.
STOT SE 3 H335 May cause respiratory irritation.
Hazards not otherwise classified
No information known.
Label elements
GHS label elements
The product is classified and labeled in accordance with 29 CFR 1910 (OSHA HCS)
Hazard pictograms

GHS02 GHS05 GHS06
Signal word
Danger
Hazard statements
H226 Flammable liquid and vapour.
H330 Fatal if inhaled.
H315 Causes skin irritation.
H318 Causes serious eye damage.
H335 May cause respiratory irritation.
Precautionary statements
P210
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P320
Specific treatment is urgent (see on this label).
P405
Store locked up.
P501
Dispose of contents/container in accordance with local/regional/national/international regulations.
WHMIS classification
B2 - Flammable liquid
D1A - Very toxic material causing immediate and serious toxic effects
D2B - Toxic material causing other toxic effects
Classification system
HMIS ratings (scale 0-4)
(Hazardous Materials Identification System)
Health (acute effects) = 4
Flammability = 3
Physical Hazard = 1
Other hazards
Results of PBT and vPvB assessment
PBT:
Not applicable.

SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS

Chemical characterization: Substances
CAS# Description:
681-84-5 Tetramethoxysilane
Identification number(s):
EC number: 211-656-4

SECTION 4. FIRST AID MEASURES

Description of first aid measures
General information
Immediately remove any clothing soiled by the product.
Remove breathing apparatus only after contaminated clothing has been completely removed.
In case of irregular breathing or respiratory arrest provide artificial respiration.
After inhalation
Supply fresh air. If required, provide artificial respiration. Keep patient warm.
Seek immediate medical advice.
After skin contact
Immediately wash with water and soap and rinse thoroughly.
Seek immediate medical advice.
After eye contact
Rinse opened eye for several minutes under running water. Then consult a doctor.
After swallowing
Seek medical treatment.
Information for doctor
Most important symptoms and effects, both acute and delayed
Causes skin irritation.
Fatal if inhaled.
Causes serious eye damage.
May cause respiratory irritation.
Indication of any immediate medical attention and special treatment needed
No further relevant information available.

SECTION 5. FIREFIGHTING MEASURES

Extinguishing media
Suitable extinguishing agents
Carbon dioxide, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Special hazards arising from the substance or mixture
If this product is involved in a fire, the following can be released:
Carbon monoxide and carbon dioxide
Silicon oxide
Advice for firefighters
Protective equipment:
Wear self-contained respirator.
Wear fully protective impervious suit.

SECTION 6. ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures
Wear protective equipment. Keep unprotected persons away.
Ensure adequate ventilation
Keep away from ignition sources
Environmental precautions:
Do not allow product to reach sewage system or any water course.
Methods and material for containment and cleaning up:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Dispose of contaminated material as waste according to section 13.
Ensure adequate ventilation.
Prevention of secondary hazards:
Keep away from ignition sources.
Reference to other sections
See Section 7 for information on safe handling
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.

SECTION 7. HANDLING AND STORAGE

Handling
Precautions for safe handling
Handle under dry protective gas.
Keep container tightly sealed.
Store in cool, dry place in tightly closed containers.
Ensure good ventilation at the workplace.
Open and handle container with care.
Information about protection against explosions and fires:
Protect against electrostatic charges.
Fumes can combine with air to form an explosive mixture.
Keep ignition sources away.
Conditions for safe storage, including any incompatibilities
Storage
Requirements to be met by storerooms and receptacles:
No special requirements.
Information about storage in one common storage facility:
Store away from water/moisture.
Store away from oxidizing agents.
Further information about storage conditions:
Store under dry inert gas.
This product is moisture sensitive.
Keep container tightly sealed.
Store in cool, dry conditions in well sealed containers.
Protect from humidity and water.
Specific end use(s)
No further relevant information available.

SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Additional information about design of technical systems:
Properly operating chemical fume hood designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.
Control parameters
Components with limit values that require monitoring at the workplace:
681-84-5 Tetramethoxysilane (100.0%)
REL (USA)
Long-term value: 6 mg/m³, 1 ppm
TLV (USA)
Long-term value: 6 mg/m³, 1 ppm
EL (Canada) Long-term value: 1 ppm
EV (Canada) Long-term value: 6.2 mg/m³, 1 ppm
Additional information:
No data
Exposure controls
Personal protective equipment
General protective and hygienic measures
The usual precautionary measures for handling chemicals should be followed.
Keep away from foodstuffs, beverages and feed.
Remove all soiled and contaminated clothing immediately.
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Avoid contact with the eyes and skin.
Maintain an ergonomically appropriate working environment.
Breathing equipment:
Use self-contained respiratory protective device in emergency situations.
Recommended filter device for short term use:
Use a respirator with multi-purpose combination (US) or type ABEK (EN 14387) as a backup to engineering controls. Risk assessment should be performed to determine if air-purifying respirators are appropriate. Only use equipment tested and approved under appropriate government standards such as NIOSH (USA) or
CEN (EU).
Protection of hands:
Impervious gloves
Check protective gloves prior to each use for their proper condition.
The selection of suitable gloves not only depends on the material, but also on quality. Quality will vary from manufacturer to manufacturer.
Material of gloves
Butyl rubber, BR
Penetration time of glove material (in minutes)
480
Glove thickness
0.3 mm
Eye protection:
Tightly sealed goggles
Body protection:
Protective work clothing.

SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties
General Information
Appearance:
Form: Liquid
Odor: Ether-like
Odor threshold: Not determined.
pH-value: Not determined.
Change in condition
Melting point/Melting range: 4-5 °C (39-41 °F)
Boiling point/Boiling range: 121-122 °C (250-252 °F)
Sublimation temperature / start: Not determined
Flash point: 26 °C (79 °F)
Flammability (solid, gaseous)
Not determined.
Ignition temperature: 245 °C (473 °F)
Decomposition temperature: Not determined
Auto igniting: Not determined.
Danger of explosion: Product is not explosive. However, formation of explosive air/vapor mixtures is possible.
Explosion limits:
Lower: 0.88 Vol %
Upper: 23.8 Vol %
Vapor pressure at 20 °C (68 °F): 18 hPa (14 mm Hg)
Density at 20 °C (68 °F): 1.032 g/cm³ (8.612 lbs/gal)
Relative density
Not determined.
Vapor density
Not determined.
Evaporation rate
Not determined.
Solubility in / Miscibility with Water: Not determined
Partition coefficient (n-octanol/water): Not determined.
Viscosity:
dynamic: Not determined.
kinematic: Not determined.
Other information
No further relevant information available.

SECTION 10. STABILITY AND REACTIVITY

Reactivity
No information known.
Chemical stability
Stable under recommended storage conditions.
Thermal decomposition / conditions to be avoided:
Decomposition will not occur if used and stored according to specifications.
Possibility of hazardous reactions
Reacts with strong oxidizing agents
Conditions to avoid
No further relevant information available.
Incompatible materials:
Water/moisture
Oxidizing agents
Hazardous decomposition products:
Carbon monoxide and carbon dioxide
Silicon oxide

SECTION 11. TOXICOLOGICAL INFORMATION

Information on toxicological effects
Acute toxicity:
Fatal if inhaled.
The Registry of Toxic Effects of Chemical Substances (RTECS) contains acute toxicity data for this substance.
LD/LC50 values that are relevant for classification:
No data
Skin irritation or corrosion:
Causes skin irritation.
Eye irritation or corrosion:
Causes serious eye damage.
Sensitization:
No sensitizing effects known.
Germ cell mutagenicity:
No effects known.
Carcinogenicity:
No classification data on carcinogenic properties of this material is available from the EPA, IARC, NTP, OSHA or ACGIH.
Reproductive toxicity:
No effects known.
Specific target organ system toxicity - repeated exposure:
No effects known.
Specific target organ system toxicity - single exposure:
May cause respiratory irritation.
Aspiration hazard:
No effects known.
Subacute to chronic toxicity:
The Registry of Toxic Effects of Chemical Substances (RTECS) contains multiple dose toxicity data for this substance.
Additional toxicological information:
To the best of our knowledge the acute and chronic toxicity of this substance is not fully known.
Carcinogenic categories
OSHA-Ca (Occupational Safety & Health Administration)
Substance is not listed.

SECTION 12. ECOLOGICAL INFORMATION

Toxicity
Aquatic toxicity:
No further relevant information available.
Persistence and degradability
No further relevant information available.
Bioaccumulative potential
No further relevant information available.
Mobility in soil
No further relevant information available.
Additional ecological information:
General notes:
Do not allow undiluted product or large quantities to reach ground water, water course or sewage system.
Avoid transfer into the environment.
Results of PBT and vPvB assessment
PBT:
Not applicable.
vPvB:
Not applicable.
Other adverse effects
No further relevant information available.

SECTION 13. DISPOSAL CONSIDERATIONS

Waste treatment methods
Recommendation
Consult state, local or national regulations to ensure proper disposal.
Uncleaned packagings:
Recommendation:
Disposal must be made according to official regulations.

SECTION 14. TRANSPORT INFORMATION

UN-Number
DOT, IMDG, IATA
UN2606
UN proper shipping name
DOT
Methyl orthosilicate
IMDG, IATA
METHYL ORTHOSILICATE
Transport hazard class(es)
DOT
Class
6.1 Toxic substances.
Label
6.1+3
Class
6.1 (TF1) Toxic substances
Label
6.1+3
IMDG, IATA
Class
6.1 Toxic substances.
Label
6.1+3
Packing group
DOT, IMDG, IATA
I
Environmental hazards:
Not applicable.
Special precautions for user
Warning: Toxic substances
Poison inhalation hazard: Yes
EMS Number: F-E,S-D
Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code
Not applicable.
Transport/Additional information:
DOT
Marine Pollutant (DOT):
No
Remarks:
This material is poisonous by inhalation in Hazard Zone B.
UN "Model Regulation":
UN2606, Methyl orthosilicate, 6.1 (3), I

SECTION 15. REGULATORY INFORMATION

Safety, health and environmental regulations/legislation specific for the substance or mixture
GHS label elements
The product is classified and labeled in accordance with 29 CFR 1910 (OSHA HCS)
Hazard pictograms
GHS02
GHS05
GHS06
Signal word
Danger
Hazard statements
H226 Flammable liquid and vapour.
H330 Fatal if inhaled.
H315 Causes skin irritation.
H318 Causes serious eye damage.
H335 May cause respiratory irritation.
Precautionary statements
P210
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P320
Specific treatment is urgent (see on this label).
P405
Store locked up.
P501
Dispose of contents/container in accordance with local/regional/national/international regulations.
National regulations
All components of this product are listed in the U.S. Environmental Protection Agency Toxic Substances Control Act Chemical substance Inventory.
All components of this product are listed on the Canadian Domestic Substances List (DSL).
SARA Section 313 (specific toxic chemical listings)
Substance is not listed.
California Proposition 65
Prop 65 - Chemicals known to cause cancer
Substance is not listed.
Prop 65 - Developmental toxicity
Substance is not listed.
Prop 65 - Developmental toxicity, female
Substance is not listed.
Prop 65 - Developmental toxicity, male
Substance is not listed.
Information about limitation of use:
For use only by technically qualified individuals.
Other regulations, limitations and prohibitive regulations
Substance of Very High Concern (SVHC) according to the REACH Regulations (EC) No. 1907/2006.
Substance is not listed.
The conditions of restrictions according to Article 67 and Annex XVII of the Regulation (EC) No 1907/2006 (REACH) for the manufacturing, placing on the market and use must be observed.
Substance is not listed.
Annex XIV of the REACH Regulations (requiring Authorisation for use)
Substance is not listed.
Chemical safety assessment:
A Chemical Safety Assessment has not been carried out.

SECTION 16. OTHER INFORMATION

Safety Data Sheet according to Regulation (EC) No. 1907/2006 (REACH). The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. American Elements shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. COPYRIGHT 1997-2022 AMERICAN ELEMENTS. LICENSED GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY.