Versatile Self-Assembly and Biosensing Applications of DNA and Carbon Quantum Dots Coordinated Cerium Ions.

Title Versatile Self-Assembly and Biosensing Applications of DNA and Carbon Quantum Dots Coordinated Cerium Ions.
Authors J. Hao; L. Wang; Y. Wang; X. Sun; G. Zhang; S. Dong
Journal Chemistry
DOI 10.1002/chem.201701709
Abstract

Self-assembly exploits noncovalent interactions to offer a facile and effective method for the soft materials construction with multi-functionalities and diversity. In this work, fluorescence carbon quantum dots with coordinated Ce3+ ions (CQDCe) were firstly synthesized and exploited as building blocks to generate a series of hierarchical structures via ionic self-assembly of CQDCe and biomolecules, DNA, myoglobin (Mb) and hyaluronic acid (HA). In particularly, the vesicles can be constructed by simple mixing oppositely-charged CQDCe and DNA in water. The formation of unusual vesicles is attributed to the further self-assembly of CQDCe with rearrange-up structure and the rigid DNA biomolecular scaffolds. This facile noncovalent self-assembly method creates the innovatory inspiration of using virgin DNA as the building motif to construct vesicles instead of sophisticated synthesis. The self-assembly of CQDCe/biopolymers was accompanied an aggregation-induced photoluminescence (PL) quenching. The biosensing platform was designed to detect polypeptides and deoxyribonuclease I through competitive binding of CQDCe and enzymatic hydrolysis of DNA backbone. We believe that the integrative self-assembly of CQDCe and DNA will enrich the theoretical study of vesicle formation by DNA molecules and extend the biological application field of fluorescence carbon quantum dots.

Citation J. Hao; L. Wang; Y. Wang; X. Sun; G. Zhang; S. Dong.Versatile Self-Assembly and Biosensing Applications of DNA and Carbon Quantum Dots Coordinated Cerium Ions.. Chemistry. 2017. doi:10.1002/chem.201701709

Related Elements

Carbon

See more Carbon products. Carbon (atomic symbol: C, atomic number: 6) is a Block P, Group 14, Period 2 element. Carbon Bohr ModelThe number of electrons in each of Carbon's shells is 2, 4 and its electron configuration is [He]2s2 2p2. In its elemental form, carbon can take various physical forms (known as allotropes) based on the type of bonds between carbon atoms; the most well known allotropes are diamond, graphite, amorphous carbon, glassy carbon, and nanostructured forms such as carbon nanotubes, fullerenes, and nanofibers . Carbon is at the same time one of the softest (as graphite) and hardest (as diamond) materials found in nature. It is the 15th most abundant element in the Earth's crust, and the fourth most abundant element (by mass) in the universe after hydrogen, helium, and oxygen. Carbon was discovered by the Egyptians and Sumerians circa 3750 BC. It was first recognized as an element by Antoine Lavoisier in 1789.

Cerium

See more Cerium products. Cerium (atomic symbol: Ce, atomic number: 58) is a Block F, Group 3, Period 6 element with an atomic weight of 140.116. The number of electrons in each of cerium's shells is 2, 8, 18, 19, 9, 2 and its electron configuration is [Xe]4f2 6s2. Cerium Bohr ModelThe cerium atom has a radius of 182.5 pm and a Van der Waals radius of 235 pm. In its elemental form, cerium has a silvery white appearance. Cerium is the most abundant of the rare earth metals. It is characterized chemically by having two valence states, the +3 cerous and +4 ceric states. The ceric state is the only non-trivalent rare earth ion stable in aqueous solutions. Elemental CeriumIt is therefore strongly acidic and oxidizing, in addition to being moderately toxic.The cerous state closely resembles the other trivalent rare earths. Cerium is found in the minerals allanite, bastnasite, hydroxylbastnasite, monazite, rhabdophane, synchysite and zircon. Cerium was discovered by Martin Heinrich Klaproth, Jöns Jakob Berzelius, and Wilhelm Hisinger in 1803 and first isolated by Carl Gustaf Mosander in 1839. The element was named after the asteroid Ceres, which itself was named after the Roman god of agriculture.

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