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Technetium
Technetium information, including Technical Data, Safety Data and its high purity properties, research, applications and other useful facts are discussed below. Scientific facts such as the atomic structure, ionization energy, abundance on Earth, conductivity and thermal properties are included.

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Technetium Bohr ModelTechnetium is a Block D, Group 7, Period 5 element. The number of electrons in each of Technetium's shells is 2, 8, 18, 13, 2 and its electronic configuration is [Kr] 4d5 5s2. In its elemental form Technetium's CAS number is 7440-26-8. The Technetium atom has a radius of 135.2.pm and it's Van der Waals radius is 200.pm.

Technetium was discovered by Carlo Perrier and Emilio Segre in 1937. Technetium is produced as a byproduct of the nuclear industry from spent nuclear fuel rods and was the first element to be made artificially. This is indicated by its name which originates from the greek word "technetos" meaning artificial.



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Technetium Abundance. The following table shows the abundance of Technetium and each of its naturally occurring isotopes on Earth along with the atomic mass for each isotope.
Isotope Atomic Mass % Abundance on Earth
Tc-98 97.907216 -
Tc-99 98.906255 -


Technetium Safety Data. The safety data for Technetium metal, nanoparticles and its compounds can vary widely depending on the form. For potential hazard information, toxicity, and road, sea and air transportation limitations, such as DOT Hazard Class, DOT Number, EU Number, NFPA Health rating and RTECS Class, please see the specific material or compound referenced in the left margin. Technetium compounds have no biological role.

Ionization Energy. The ionization energy for Technetium (the least required energy to release a single electron from the atom in it's ground state in the gas phase) is stated in the following table:
1st Ionization Energy 702.42 kJ mol-1
2nd Ionization Energy 702.42 kJ mol-1
3rd Ionization Energy 2850.20 kJ mol-1


Conductivity. As to Technetium's electrical and thermal conductivity, the electrical conductivity measured in terms of electrical resistivity @ 20 ºC is 16.9 µOcm and its electronegativities (or its ability to draw electrons relative to other elements) is 2.1. The thermal conductivity of Technetium is 50.6 W m-1 K-1.

Thermal Properties of Technetium. The melting point and boiling point for Technetium are stated below. The following chart sets forth the heat of fusion, heat of vaporization and heat of atomization.
Heat of Fusion 23.81 kJ mol-1
Heat of Vaporization 585.22 kJ mol-1
Heat of Atomization 678 kJ mol-1


Recent Research & Development for Technetium
  • F-18 FDG PET/CT and Tc-99m Sulfur Colloid SPECT imaging in the diagnosis and treatment of a case of dual solitary fibrous tumors of the retroperitoneum and pancreas. Azadi J, Subhawong A, Durand DJ. J Radiol Case Rep. 2012;6(3):32-7. Epub 2012 Mar 1. PMID: 22690289 [PubMed - in process] Free PMC Article

  • Assessment of cerebral blood flow findings using 99mTc-ECD single-photon emission computed tomography in patients diagnosed with major depressive disorder. Nagafusa Y, Okamoto N, Sakamoto K, Yamashita F, Kawaguchi A, Higuchi T, Matsuda H. J Affect Disord. 2012 Jun 6. [Epub ahead of print] PMID: 22682101 [PubMed - as supplied by publisher]

  • TNF-a neutralization improves experimental hepatopulmonary syndrome in rats. Liu L, Liu N, Zhao Z, Liu J, Feng Y, Jiang H, Han D. Liver Int. 2012 Jul;32(6):1018-26. doi: 10.1111/j.1478-3231.2012.02821.x. PMID: 22672643 [PubMed - in process]

  • An occult filarial infection presenting as chyluria with proteinuria: a case report and review of literature. Saha M, Ray S, Goswami M, Kundu S, Saha P, Saha A, Maitra S, Talukdar A. BMJ Case Rep. 2012 Jun 1;2012. pii: bcr0120125635. doi: 10.1136/bcr.01.2012.5635. PMID: 22669920 [PubMed - in process]

  • Use of SPECT to detect changes in diastolic and coronary reserve in patients with obstructive sleep apnea. Wang B, Liu ZL, Niu B, Liang HW, Qiao RL. Sleep Breath. 2012 Jun 3. [Epub ahead of print] PMID: 22661252 [PubMed - as supplied by publisher]

  • Diagnostic accuracy of sentinel node in endometrial cancer by using hysteroscopic injection of radiolabeled tracer. Solima E, Martinelli F, Ditto A, Maccauro M, Carcangiu M, Mariani L, Kusamura S, Fontanelli R, Grijuela B, Raspagliesi F. Gynecol Oncol. 2012 May 30. [Epub ahead of print] PMID: 22659192 [PubMed - as supplied by publisher]

  • Synthesis and biological evaluation of novel technetium-99m labeled phenylbenzoxazole derivatives as potential imaging probes for ß-amyloid plaques in brain. Wang X, Cui M, Yu P, Li Z, Yang Y, Jia H, Liu B. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4327-31. Epub 2012 May 11. PMID: 22652052 [PubMed - in process]

  • Liver analysis using gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging: Correlation with histological grading and quantitative liver evaluation prior to hepatectomy. Kumazawa K, Edamoto Y, Yanase M, Nakayama T. Hepatol Res. 2012 Apr 17. doi: 10.1111/j.1872-034X.2012.01027.x. [Epub ahead of print] PMID: 22647151 [PubMed - as supplied by publisher]

  • (99m)Tc-albumin can replace (125)I-albumin to determine plasma volume repeatedly. Bonfils PK, Damgaard M, Stokholm KH, Nielsen SL. Scand J Clin Lab Invest. 2012 May 31. [Epub ahead of print] PMID: 22646079 [PubMed - as supplied by publisher]

  • Radiolabeling of folate targeted multifunctional conjugate with Technetium-99m and biodistribution studies in rats. Ak G, Yurt Lambrecht F, Sanlier SH. J Drug Target. 2012 Jul;20(6):509-14. PMID: 22643314 [PubMed - in process]

  • Synthesis of [DTPA-bis(D-ser)] Chelate (DBDSC): An Approach for the Design of SPECT Radiopharmaceuticals Based on Technetium. Varshney R, Sethi SK, Hazari PP, Chuttani K, Soni S, Milton MD, Mishra AK. Curr Radiopharm. 2012 May 29. [Epub ahead of print] PMID: 22642421 [PubMed - as supplied by publisher]

  • Future of Low Specific Activity Molybdenum-99/Technetium-99m Generator. Mushtaq A. Curr Radiopharm. 2012 May 29. [Epub ahead of print] PMID: 22642420 [PubMed - as supplied by publisher]

  • Technetium-99m New Production and Processing Strategies to Provide Adequate Levels for SPECT Imaging. Osso JA, Catanoso MF, Barrio G, Brambilla TP, Teodoro R, Dias CR, Suzuki KN. Curr Radiopharm. 2012 May 29. [Epub ahead of print] PMID: 22642387 [PubMed - as supplied by publisher]

  • Sentinel lymph node biopsy in penile carcinoma. Horenblas S. Semin Diagn Pathol. 2012 May;29(2):90-5. PMID: 22641958 [PubMed - in process]

  • Evaluation of coronary artery abnormalities in Williams syndrome patients using myocardial perfusion scintigraphy and CT angiography. Ergul Y, Nisli K, Kayserili H, Karaman B, Basaran S, Dursun M, Yilmaz E, Ergul N, Unal SN, Dindar A. Cardiol J. 2012;19(3):301-8. PMID: 22641550 [PubMed - in process]

  • Molybdenum-99 production from reactor irradiation of molybdenum targets - A viable strategy for enhanced availability of technetium-99m. Pillai MR, Russ Knapp FF. Q J Nucl Med Mol Imaging. 2012 May 28. [Epub ahead of print] PMID: 22641275 [PubMed - as supplied by publisher]

  • Toxicity Studies of Poly(Anhydride) Nanoparticles as Carriers for Oral Drug Delivery. Ojer P, de Cerain AL, Areses P, Peñuelas I, Irache JM. Pharm Res. 2012 May 26. [Epub ahead of print] PMID: 22638871 [PubMed - as supplied by publisher]

  • A NOVEL DEVICE FOR AUTOMATIC WITHDRAWAL AND ACCURATE CALIBRATION OF 99m-TECHNETIUM RADIOPHARMACEUTICALS TO MINIMISE RADIATION EXPOSURE TO NUCLEAR MEDICINE STAFF AND PATIENT. Nazififard M, Mahdizadeh S, Meigooni AS, Alavi M, Suh KY. Radiat Prot Dosimetry. 2012 May 23. [Epub ahead of print] PMID: 22628527 [PubMed - as supplied by publisher]

  • 99mTc(CO)3-Ibritumomab tiuxetan; a novel radioimmunoimaging (RII) agent of B cell non-Hodgkin's lymphoma (NHL). Shah SQ, Khan AU, Khan MR. Biol Chem. 2012 Jan 1;393(1-2):71-5. doi: 10.1515/BC-2011-170. PMID: 22628300 [PubMed - in process]

  • In the workup of patients with obscure gastrointestinal bleed, does 64-slice MDCT have a role? Kulkarni C, Moorthy S, Sreekumar K, Rajeshkannan R, Nazar P, Sandya C, Sivasubramanian S, Ramchandran P. Indian J Radiol Imaging. 2012 Jan;22(1):47-53. PMID: 22623816 [PubMed - in process]





  •  
    Formula Atomic Number Molecular Weight Electronegativity (Pauling) Density Melting Point Boiling Point Vanderwaals radius Ionic radius Energy of first ionization
    Tc 43 [98](0) g.mol -1 2.1 11 g·cm−3 2157  °C 4265 °C .200 nm - pm 702.42  kJ.mol-1

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