About Benzoates

Benzoate Formula Diagram (C6H5CO2)

Benzoates are salts or esters of benzoic acid. The systematic name for benzoate is benzenecarboxylate. Notable types of these compounds used in industry include sodium benzoate and potassium benzoates, which are both used widely as preservatives in food, medicine, and cosmetics. Organic benzoates are often used as organic solvents or as plasticizers. Additionally, some organic benzoates have useful properties as pharmaceuticals; notably, benzyl benzoate is an effective and inexpensive repellant and/or treatment for a variety of infectious insects, worms, and mites, and is used in both human and veterinary medicine.

Recent Research & Development for Benzoates

Structural sensitivity of CH vibrational band in methyl benzoate., Roy, Susmita, and Maiti Kiran Sankar , Spectrochim Acta A Mol Biomol Spectrosc, 2018 May 05, Volume 196, p.289-294, (2018)

A Predictive Model for the Decarboxylation of Silver Benzoate Complexes Relevant to Decarboxylative Coupling Reactions., Crovak, Robert A., and Hoover Jessica M. , J Am Chem Soc, 2018 Feb 21, Volume 140, Issue 7, p.2434-2437, (2018)

Blanching and antimicrobial mixture (potassium sorbate-sodium benzoate) impact on the stability of a tamarillo () sweet product preserved by hurdle technology., Preciado-Iñiga, Grace E., Amador-Espejo Genaro G., and Bárcenas María E. , J Food Sci Technol, 2018 Feb, Volume 55, Issue 2, p.740-748, (2018)

Modelling the effects of lactic acid, sodium benzoate and temperature on the growth of Candida maltosa., Valík, Ľ, Ačai P, and Liptáková D , Lett Appl Microbiol, 2017 Nov, Volume 65, Issue 5, p.453-460, (2017)

Assessment of the Target Engagement and D-Serine Biomarker Profiles of the D-Amino Acid Oxidase Inhibitors Sodium Benzoate and PGM030756., Howley, Eimear, Bestwick Michael, Fradley Rosa, Harrison Helen, Leveridge Mathew, Okada Kengo, Fieldhouse Charlotte, Farnaby Will, Canning Hannah, Sykes Andy P., et al. , Neurochem Res, 2017 Nov, Volume 42, Issue 11, p.3279-3288, (2017)

A two-dimensional copper(II) coordination polymer based on 2,4'-oxybis(benzoate) and 4,4'-bipyridine., Tang, Long, Zhang Juan, Liu Xiao Xia, Wang Ji Jiang, and Fu Feng , Acta Crystallogr C Struct Chem, 2017 Jul 01, Volume 73, Issue Pt 7, p.503-507, (2017)

Potassium 2-(l-hydroxypentyl)-benzoate attenuates neuroinflammatory responses and upregulates heme oxygenase-1 in systemic lipopolysaccharide-induced inflammation in mice., Zhao, Chunyang, Hou Weizhen, Lei Hui, Huang Longjian, Wang Shan, Cui Dandan, Xing Changhong, Wang Xiaoliang, and Peng Ying , Acta Pharm Sin B, 2017 Jul, Volume 7, Issue 4, p.470-478, (2017)

Crystal structures of (E)-4-[1-(2-carbamo-thio-yl-hydrazinyl-idene)eth-yl]phenyl acetate and (E)-4-[1-(2-carbamo-thio-ylhydrazinyl-idene)eth-yl]phenyl benzoate., Viswanathan, Vijayan, Ananth Mani Karthik, Narasimhan S, and Velmurugan Devadasan , Acta Crystallogr E Crystallogr Commun, 2017 Jan 01, Volume 73, Issue Pt 1, p.20-23, (2017)

Neutral losses of sodium benzoate and benzoic acid in the fragmentation of the [M + Na](+) ions of methoxyfenozide and tebufenozide via intramolecular rearrangement in electrospray ionization tandem mass spectrometry., Chai, Yunfeng, Gao Guanwei, Shen Shanshan, Liu Xin, and Lu Chengyin , Rapid Commun Mass Spectrom, 2017 Feb 15, Volume 31, Issue 3, p.245-252, (2017)

Effects of sodium benzoate, a commonly used food preservative, on learning, memory, and oxidative stress in brain of mice., Khoshnoud, Mohammad Javad, Siavashpour Asma, Bakhshizadeh Mojgan, and Rashedinia Marzieh , J Biochem Mol Toxicol, 2017 Dec 15, (2017)

The efficacy of sodium benzoate as an adjunctive treatment in early psychosis - CADENCE-BZ: study protocol for a randomized controlled trial., Ryan, Alex, Baker Andrea, Dark Frances, Foley Sharon, Gordon Anne, Hatherill Sean, Stathis Stephen, Saha Sukanta, Bruxner George, Beckman Martin, et al. , Trials, 2017 Apr 07, Volume 18, Issue 1, p.165, (2017)

Toxicokinetics and toxicity of potassium 2-(1-hydroxypentyl)-benzoate in beagle dogs., Li, Jiang, Wang Xiao-Liang, Wang Ai-Ping, Xu Shao-Feng, and Jin Hong-Tao , J Asian Nat Prod Res, 2017 Apr, Volume 19, Issue 4, p.388-401, (2017)

A Patient with MSUD: Acute Management with Sodium Phenylacetate/Sodium Benzoate and Sodium Phenylbutyrate., Köse, Melis, Canda Ebru, Kagnici Mehtap, Uçar Sema Kalkan, and Çoker Mahmut , Case Rep Pediatr, 2017, Volume 2017, p.1045031, (2017)

In Vitro Effects of Sodium Benzoate on Th1/Th2 Deviation in Patients with Multiple Sclerosis., Rezaei, N, Amirghofran Z, Nikseresht A, Ashjazade N, Zoghi S, Tahvili S, and Kamali-Sarvestani E , Immunol Invest, 2016 Sep 9, p.1-13, (2016)