About Benzoates

Benzoate Formula Diagram (C6H5CO2)

Benzoates are salts or esters of benzoic acid. The systematic name for benzoate is benzenecarboxylate. Notable types of these compounds used in industry include sodium benzoate and potassium benzoates, which are both used widely as preservatives in food, medicine, and cosmetics. Organic benzoates are often used as organic solvents or as plasticizers. Additionally, some organic benzoates have useful properties as pharmaceuticals; notably, benzyl benzoate is an effective and inexpensive repellant and/or treatment for a variety of infectious insects, worms, and mites, and is used in both human and veterinary medicine.

American Elements manufactures multiple forms of benzoate compounds including solutions, nanopowders, submicron, and -325 mesh powders, and high surface area materials with particle distribution and particle size controlled and certified. We also produce larger -40 mesh, -100 mesh, -200 mesh range sizes and <0.5 mm, 2 mm, 5 mm and other sizes of shot, granules, lump, flake and pieces. Purities include 99%, 99.9%, 99.99%, 99.999% and 99.9999% (2N, 3N, 4N, 5N and 6N).

American Elements maintains industrial scale production for all its benzoate products and will execute Non-Disclosure or Confidentiality Agreements to protect customer know-how.

Recent Research & Development for Benzoates

β-Estradiol-3-benzoate confers neuroprotection in Parkinson MPP(+) rat model through inhibition of lipid peroxidation., Aguirre-Vidal, Yoshajandith, Monroy-Noyola Antonio, Anaya-Ramos Laura, Arteaga-Silva Marcela, Mendez-Armenta Marisela, Ostoa-Saloma Pedro, Díaz-Zaragoza Mariana, Morales-Montor Jorge, Rios Camilo, and Montes Sergio , Steroids, 2017 Oct, Volume 126, p.7-14, (2017)

Assessment of the Target Engagement and D-Serine Biomarker Profiles of the D-Amino Acid Oxidase Inhibitors Sodium Benzoate and PGM030756., Howley, Eimear, Bestwick Michael, Fradley Rosa, Harrison Helen, Leveridge Mathew, Okada Kengo, Fieldhouse Charlotte, Farnaby Will, Canning Hannah, Sykes Andy P., et al. , Neurochem Res, 2017 Nov, Volume 42, Issue 11, p.3279-3288, (2017)

Diethylamino hydroxybenzoyl hexyl benzoate (DHHB) as additive to the UV filter avobenzone in cosmetic sunscreen formulations - Evaluation of the photochemical behavior and photostabilizing effect., Kawakami, Camila Martins, Máximo Leandro Nériton C., Fontanezi Bianca Bueno, da Silva Roberto Santana, and Gaspar Lorena Rigo , Eur J Pharm Sci, 2017 Mar 01, Volume 99, p.299-309, (2017)

The Clinical Follow-Up of Estradiol Benzoate Priming During Induction of Estrus With Cabergoline in Dogs., Mogheiseh, Asghar, Ghiri Mohammad Javad Mosa, and Bandarian Esmaeil , Top Companion Anim Med, 2017 Mar, Volume 32, Issue 1, p.16-19, (2017)

Intragastric infusion of denatonium benzoate attenuates interdigestive gastric motility and hunger scores in healthy female volunteers., Deloose, Eveline, Janssen Pieter, Corsetti Maura, Biesiekierski Jessica, Masuy Imke, Rotondo Alessandra, Van Oudenhove Lukas, Depoortere Inge, and Tack Jan , Am J Clin Nutr, 2017 Mar, Volume 105, Issue 3, p.580-588, (2017)

Cytotoxic activity of alkyl benzoate and fatty acids from the red sea sponge Hyrtios erectus., Hawas, Usama W., El-Kassem Lamia T. Abou, Abdelfattah Mohamed S., I Y Elmallah Mohammed, Eid Mennat Allah G., Monier Marwa, and Nithiyanandam M , Nat Prod Res, 2017 Jul 03, p.1-6, (2017)

A two-dimensional copper(II) coordination polymer based on 2,4'-oxybis(benzoate) and 4,4'-bipyridine., Tang, Long, Zhang Juan, Liu Xiao Xia, Wang Ji Jiang, and Fu Feng , Acta Crystallogr C Struct Chem, 2017 Jul 01, Volume 73, Issue Pt 7, p.503-507, (2017)

Potassium 2-(l-hydroxypentyl)-benzoate attenuates neuroinflammatory responses and upregulates heme oxygenase-1 in systemic lipopolysaccharide-induced inflammation in mice., Zhao, Chunyang, Hou Weizhen, Lei Hui, Huang Longjian, Wang Shan, Cui Dandan, Xing Changhong, Wang Xiaoliang, and Peng Ying , Acta Pharm Sin B, 2017 Jul, Volume 7, Issue 4, p.470-478, (2017)

Benzoate- and Salicylate-Tolerant Strains of Escherichia coli K-12 Lose Antibiotic Resistance during Laboratory Evolution., Creamer, Kaitlin E., Ditmars Frederick S., Basting Preston J., Kunka Karina S., Hamdallah Issam N., Bush Sean P., Scott Zachary, He Amanda, Penix Stephanie R., Gonzales Alexandra S., et al. , Appl Environ Microbiol, 2017 Jan 15, Volume 83, Issue 2, (2017)

Crystal structures of (E)-4-[1-(2-carbamo-thio-yl-hydrazinyl-idene)eth-yl]phenyl acetate and (E)-4-[1-(2-carbamo-thio-ylhydrazinyl-idene)eth-yl]phenyl benzoate., Viswanathan, Vijayan, Ananth Mani Karthik, Narasimhan S, and Velmurugan Devadasan , Acta Crystallogr E Crystallogr Commun, 2017 Jan 01, Volume 73, Issue Pt 1, p.20-23, (2017)

Crystal structure of 2-oxo-2H-chromen-3-yl 4-chloro-benzoate and Hirshfeld surface analysis., Ziki, Eric, Sosso Siaka, Mansilla-Koblavi Frédérica, Djandé Abdoulaye, and Kakou-Yao Rita , Acta Crystallogr E Crystallogr Commun, 2017 Jan 01, Volume 73, Issue Pt 1, p.45-47, (2017)

Ovulation synchronization with estradiol benzoate or GnRH in a timed artificial insemination protocol in buffalo cows and heifers during the nonbreeding season., Carvalho, N A. T., Soares J G., Souza D C., Maio J R. G., Sales J N. S., B Júnior Martins, Macari R C., D'Occhio M J., and Baruselli P S. , Theriogenology, 2017 Jan 01, Volume 87, p.333-338, (2017)

Consecutive emamectin benzoate and deltamethrin treatments affect the expressions and activities of detoxification enzymes in the rainbow trout (Oncorhynchus mykiss)., Cárcamo, Juan Guillermo, Aguilar Marcelo N., Carreño Constanza F., Vera Tamara, Arias-Darraz Luis, Figueroa Jaime E., Romero Alex P., Alvarez Marco, and Yáñez Alejandro J. , Comp Biochem Physiol C Toxicol Pharmacol, 2017 Jan, Volume 191, p.129-137, (2017)

Kinetics of interaction between substrates/substrate analogs and benzoate 1,2-dioxygenase from benzoate-degrading Rhodococcus opacus 1CP., Solyanikova, Inna P., Borzova Oksana V., and Emelyanova Elena V. , Folia Microbiol (Praha), 2017 Feb 24, (2017)