About Perchlorates

Perchlorate Formula Diagram (ClO4-)

Perchlorates are salts derived from perchloric acid, a monobasic acid stronger than sulfuric and nitric acids and an exceptionally powerful oxidizer. This high reactivity makes perchloric acid and many of its derivitives exceedingly useful in a variety of industrial processes, though it also dictates that these compounds should be handled with care. Alone, the perchlorate salts will not catch fire or explode, but in combination with organic compounds can serve as rocket fuel or pyrotechnic agents. Perchlorates are additionally found in airbags, tire pressure monitor valve sensors, and some batteries. Perchlorates are known to have pronounced biological effects, particularly on the thyroid gland in humans. This is useful in the context of hyperthyroidism, as perchlorates can inhibit the overproduction of thyroid hormones, though this is no longer the primary method available for treating this condition. However, perchlorates have other potential negative effects on biological systems, and perchlorate contamination from industrial use of these chemicals is a significant environmental problem.

Recent Research & Development for Perchlorates

The discrimination of 72 nitrate, chlorate and perchlorate salts using IR and Raman spectroscopy., Zapata, Félix, and García-Ruiz Carmen , Spectrochim Acta A Mol Biomol Spectrosc, 2018 Jan 15, Volume 189, p.535-542, (2018)

Vibrational spectra, normal coordinate analysis, and hydrogen bond investigation of pyridinium perchlorate., Omidvar, Bibi Amineh, Tayyari Sayyed Faramarz, Vakili Mohammad, and Nekoei Abdo-Reza , Spectrochim Acta A Mol Biomol Spectrosc, 2018 Feb 15, Volume 191, p.558-565, (2018)

Dracorhodin perchlorate regulates fibroblast proliferation to promote rat's wound healing., Jiang, Xiaowen, Liu Lin, Qiao Lu, Zhang Binqing, Wang Xuewei, Han Yuwen, and Yu Wenhui , J Pharmacol Sci, 2018 Feb 07, (2018)

Anthropogenic Perchlorate Increases since 1980 in the Canadian High Arctic., Furdui, Vasile I., Zheng Jiancheng, and Furdui Andreea , Environ Sci Technol, 2018 Feb 06, Volume 52, Issue 3, p.972-981, (2018)

Triethanolaminate iron perchlorate revisited: change of space group, chemical composition and oxidation states in [Fe7(tea)3(tea-H)3](ClO4)2 (tea-H3 is triethanolamine)., van der Horn, Jitschaq A., and Lutz Martin , Acta Crystallogr C Struct Chem, 2018 Feb 01, Volume 74, Issue Pt 2, p.125-130, (2018)

Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor., Alterio, Vincenzo, Esposito Davide, Monti Simona Maria, Supuran Claudiu T., and De Simone Giuseppina , J Enzyme Inhib Med Chem, 2018 Dec, Volume 33, Issue 1, p.151-157, (2018)

A fluorophore-labelled copper complex: crystal structure, hybrid cyclic water-perchlorate cluster and biological properties., Bhat, Satish S., Revankar Vidyanand K., Shivalingegowda Naveen, and Lokanath N K. , Acta Crystallogr C Struct Chem, 2017 Sep 01, Volume 73, Issue Pt 9, p.710-717, (2017)

The rapid adsorption-microbial reduction of perchlorate from aqueous solution by novel amine-crosslinked magnetic biopolymer resin., Song, Wen, Gao Baoyu, Wang Hailan, Xu Xing, Xue Moxi, Zha Minchao, and Gong Bo , Bioresour Technol, 2017 Sep, Volume 240, p.68-76, (2017)

Distinct room-temperature dielectric transition in a perchlorate-based organic-inorganic hybrid perovskite., Sun, Yu-Ling, Shi Chao, and Zhang Wen , Dalton Trans, 2017 Nov 17, (2017)

Urinary Iodine, Perchlorate, and Thiocyanate Concentrations in U.S. Lactating Women., Lee, Sun Y., McCarthy Alicia M., Stohl Hindi E., Ibrahim Sherrine A., Jeong Christina, Braverman Lewis E., Ma Wendy Siqian, He Xuemei, Mestman Jorge H., Schuller Kristin E., et al. , Thyroid, 2017 Nov 12, (2017)

Use of the fluorescent dye tetramethylrhodamine methyl ester perchlorate for mitochondrial membrane potential assessment in human spermatozoa., Uribe, P, Villegas J V., Boguen R, Treulen F, Sánchez R, Mallmann P, Isachenko V, Rahimi G, and Isachenko E , Andrologia, 2017 Nov, Volume 49, Issue 9, (2017)

Low-temperature, high-mobility, solution-processed metal oxide semiconductors fabricated with oxygen radical assisted perchlorate aqueous precursors., Gao, Peixiong, Lan Linfeng, Lin Zhenguo, Sun Sheng, Li Yuzhi, Song Wei, Song Erlong, Zhang Peng, and Peng Junbiao , Chem Commun (Camb), 2017 May 31, (2017)

Electrode potential dependent desolvation and resolvation of germanium(100) in contact with aqueous perchlorate electrolytes., Niu, Fang, Schulz Rainer, Medina Arcesio Castañeda, Schmid Rochus, and Erbe Andreas , Phys Chem Chem Phys, 2017 May 31, Volume 19, Issue 21, p.13585-13595, (2017)

An improved size exclusion-HPLC method for molecular size distribution analysis of immunoglobulin G using sodium perchlorate in the eluent., Wang, Hsiaoling, Levi Mark S., Del Grosso Alfred V., McCormick William M., and Bhattacharyya Lokesh , J Pharm Biomed Anal, 2017 May 10, Volume 138, p.330-343, (2017)