tracking of adipose tissue grafts with cadmium-telluride quantum dots.

Title tracking of adipose tissue grafts with cadmium-telluride quantum dots.
Authors C.J. Deglmann; K. B?a?ków-Schmalzbauer; S. Moorkamp; J. Wallmichrath; R.E. Giunta; A.L. Rogach; E. Wagner; R.G. Baumeister; M. Ogris
Journal Arch Plast Surg
DOI 10.5999/aps.2017.01487
Abstract

BACKGROUND: Fat grafting, or lipofilling, represent frequent clinically used entities. The fate of these transplants is still not predictable, whereas only few animal models are available for further research. Quantum dots (QDs) are semiconductor nanocrystals which can be conveniently tracked due to photoluminescence.

METHODS: Fat grafts in cluster form were labeled with cadmium-telluride (CdTe)-QD 770 and transplanted subcutaneously in a murine model. Photoluminescence levels were serially followed .

RESULTS: Tracing of fat grafts was possible for 50 days with CdTe-QD 770. The remaining photoluminescence was 4.9%±2.5% for the QDs marked fat grafts after 30 days and 4.2%± 1.7% after 50 days. There was no significant correlation in the relative course of the tracking signal, when vital fat transplants were compared to non-vital graft controls.

CONCLUSIONS: For the first-time fat grafts were tracked with CdTe-QDs. CdTe-QDs could offer a new option for tracking of fat grafts for at least 50 days, but do not document vitality of the grafts.

Citation C.J. Deglmann; K. B?a?ków-Schmalzbauer; S. Moorkamp; J. Wallmichrath; R.E. Giunta; A.L. Rogach; E. Wagner; R.G. Baumeister; M. Ogris.tracking of adipose tissue grafts with cadmium-telluride quantum dots.. Arch Plast Surg. 2018;45(2):111117. doi:10.5999/aps.2017.01487

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