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Recent Research & Development for Lutetium
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Initial Characterization of a Dedicated Breast PET/CT Scanner During Human Imaging.
Bowen SL, Wu Y, Chaudhari AJ, Fu L, Packard NJ, Burkett GW, Yang K, Lindfors KK, Shelton DK, Hagge R, Borowsky AD, Martinez SR, Qi J, Boone JM, Cherry SR, Badawi RD.
J Nucl Med. 2009 Aug 18. [Epub ahead of print]
PMID: 19690029 [PubMed - as supplied by publisher]
- Molecular semiconductor-doped insulator (MSDI) heterojunctions: an alternative transducer for gas chemosensing.
Parra V, Brunet J, Pauly A, Bouvet M.
Analyst. 2009 Sep;134(9):1776-8. Epub 2009 May 29.
PMID: 19684897 [PubMed - in process]
- Management of Advanced Neuroendocrine Tumors With Hepatic Metastasis.
Khasraw M, Gill A, Harrington T, Pavlakis N, Modlin I.
J Clin Gastroenterol. 2009 Aug 3. [Epub ahead of print]
PMID: 19654558 [PubMed - as supplied by publisher]
- A Position Sensitive Gamma-Ray Scintillator Detector With Enhanced Spatial Resolution, Linearity and Field of View.
Domingo-Pardo C, Goel N, Engert T, Gerl J, Isaka M, Kojouharov I, Schaffner H.
IEEE Trans Med Imaging. 2009 Jul 21. [Epub ahead of print]
PMID: 19628451 [PubMed - as supplied by publisher]
- Spherical core-shell structured nanophosphors on the basis of europium-doped lutetium compounds.
Yermolayeva YV, Tolmachev AV, Korshikova TI, Yavetskiy RP, Dobrotvorskaya MV, Danylenko NI, Sofronov DS.
Nanotechnology. 2009 Aug 12;20(32):325601. Epub 2009 Jul 21.
PMID: 19620751 [PubMed - in process]
- Novel Neurotensin Analogues for Radioisotope Targeting to Neurotensin Receptor-Positive Tumors.
Alshoukr F, Rosant C, Maes V, Abdelhak J, Raguin O, Burg S, Sarda L, Barbet J, Tourwe´ D, Pelaprat D, Gruaz-Guyon A.
Bioconjug Chem. 2009 Jul 17. [Epub ahead of print]
PMID: 19610615 [PubMed - as supplied by publisher]
- The imaging performance of compact Lu2O3:Eu powdered phosphor screens: Monte Carlo simulation for applications in mammography.
Liaparinos PF, Kandarakis IS.
Med Phys. 2009 Jun;36(6):1985-97.
PMID: 19610287 [PubMed - indexed for MEDLINE]
- Peptide-targeted diagnostics and radiotherapeutics.
Tweedle MF.
Acc Chem Res. 2009 Jul 21;42(7):958-68.
PMID: 19552403 [PubMed - in process]
- Lanthanide Complexes of Triethylenetetramine Tetra-, Penta-, and Hexaacetamide Ligands as Paramagnetic Chemical Exchange-Dependent Saturation Transfer Contrast Agents for Magnetic Resonance Imaging: Nona- versus Decadentate Coordination.
Burdinski D, Pikkemaat JA, Lub J, de Peinder P, Nieto Garrido L, Weyhermu¨ller T.
Inorg Chem. 2009 Jun 9. [Epub ahead of print]
PMID: 19507818 [PubMed - as supplied by publisher]
- Comparison of imaging protocols for 18F-FDG PET/CT in overweight patients: optimizing scan duration versus administered dose.
Masuda Y, Kondo C, Matsuo Y, Uetani M, Kusakabe K.
J Nucl Med. 2009 Jun;50(6):844-8. Epub 2009 May 14.
PMID: 19443586 [PubMed - indexed for MEDLINE]
- Radiolabeling of trastuzumab with 177Lu via DOTA, a new radiopharmaceutical for radioimmunotherapy of breast cancer.
Rasaneh S, Rajabi H, Babaei MH, Daha FJ, Salouti M.
Nucl Med Biol. 2009 May;36(4):363-9.
PMID: 19423003 [PubMed - indexed for MEDLINE]
- Novel electro-optical coupling technique for magnetic resonance-compatible positron emission tomography detectors.
Olcott PD, Peng H, Levin CS.
Mol Imaging. 2009 Mar-Apr;8(2):74-86.
PMID: 19397853 [PubMed - indexed for MEDLINE]
- Redox properties of mixed lutetium/yttrium nitride clusterfullerenes: endohedral Lu(x)Y(3-x)N@C80(I) (x = 0-3) compounds.
Tarábek J, Yang S, Dunsch L.
Chemphyschem. 2009 May 11;10(7):1037-43.
PMID: 19360798 [PubMed - indexed for MEDLINE]
- Tissue drug concentration determines whether fluorescence or absorption measurements are more sensitive in diffuse optical tomography of exogenous contrast agents.
Davis SC, Pogue BW, Dehghani H, Paulsen KD.
Appl Opt. 2009 Apr 1;48(10):D262-72.
PMID: 19340118 [PubMed - indexed for MEDLINE]
- Radiolabeling of monoclonal anti-CD105 with (177)Lu for potential use in radioimmunotherapy.
Lee SY, Hong YD, Felipe PM, Pyun MS, Choi SJ.
Appl Radiat Isot. 2009 Jul-Aug;67(7-8):1366-9. Epub 2009 Feb 25.
PMID: 19324561 [PubMed - indexed for MEDLINE]
- Radiolabeling of monoclonal anti-vascular endothelial growth factor receptor 1 (VEGFR 1) with (177)Lu for potential use in radioimmunotherapy.
Lee SY, Hong YD, Pyun MS, Felipe PM, Choi SJ.
Appl Radiat Isot. 2009 Jul-Aug;67(7-8):1185-9. Epub 2009 Feb 14.
PMID: 19324558 [PubMed - indexed for MEDLINE]
- [Peptide receptor radionuclide therapy of neuroendocrine tumors]
Arveschoug AK, Hjorthaug K, Rehling M, Højgaard L, Mortensen J, Oturai PS.
Ugeskr Laeger. 2009 Mar 23;171(13):1073. Danish. No abstract available.
PMID: 19321068 [PubMed - indexed for MEDLINE]
- Theoretical study on local defect structure of (FeO4)(5-) clusters in YGG and LGG crystals.
Li HL, Kuang XY, Li Y, Mao AJ.
Spectrochim Acta A Mol Biomol Spectrosc. 2009 Jul 15;73(2):273-6. Epub 2009 Feb 21.
PMID: 19297241 [PubMed - indexed for MEDLINE]
- [PET-CT for neuroendocrine tumors and nuclear medicine therapy options]
Scheidhauer K, Miederer M, Gaertner FC.
Radiologe. 2009 Mar;49(3):217-23. Review. German.
PMID: 19296068 [PubMed - indexed for MEDLINE]
- Continuous depth-of-interaction encoding using phosphor-coated scintillators.
Du H, Yang Y, Glodo J, Wu Y, Shah K, Cherry SR.
Phys Med Biol. 2009 Mar 21;54(6):1757-71. Epub 2009 Mar 3.
PMID: 19258685 [PubMed - indexed for MEDLINE]
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Material Safety Data Plate |
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1 Identification of substance
- Product details
- Trade name Lutetium metal
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2 Composition/Data on components:
- Chemical characterization:
Designation: (CAS#)
Lutetium (CAS# 7439-94-3), 100%
- Identification number(s):
- EINECS Number: 231-103-0
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3 Hazards identification
- Hazard designation: · void
- Information pertaining to particular dangers for man and environment
Fine powder:
R 11 Highly flammable
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4 First aid measures
- General information No special measures required.
- After inhalation No special measures required.
- After skin contact The product is not skin irritating.
- After eye contact Seek medical treatment in case of complaints.
- After swallowing Seek medical treatment in case of complaints.
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5 Fire fighting measures
- Suitable extinguishing agents Extinguishing powder. Do not use water.
- For safety reasons unsuitable extinguishing agents Water.
- Protective equipment: No special measures required.
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6 Accidental release measures
- Person-related safety precautions: Not required.
- Measures for environmental protection:
Do not allow material to be released to the environment without proper governmental permits.
- Measures for cleaning/collecting: Collect mechanically.
- Additional information:
See Section 7 for information on safe handling
See section 8 for information on personal protection equipment.
See Section 13 for information on disposal.
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7 Handling and storage
- Handling
- Information for safe handling:
Handle under dry protective gas.
Keep containers tightly sealed.
Store in cool, dry place in tightly closed containers.
No special precautions necessary if used correctly.
- Information about protection against explosions and fires:
Fine powder: highly flammable
- Storage
- Requirements to be met by storerooms and containers:
No special requirements.
- Information about storage in one common storage facility:
Store away from air.
Store away from water.
Do not store together with oxidizing and acidic materials.
Store away from halogens.
- Further information about storage conditions:
Store under dry inert gas.
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8 Exposure controls and personal protection
- Additional information about design of technical systems:
No further data; see item 7.
- Components with critical values that require monitoring at the
workplace:
Not required.
- Additional information: No data
- Personal protective equipment
- General protective and hygienic measures
The usual precautionary measures should be adhered to in handling the chemicals.
- Breathing equipment: Not required.
- Protection of hands: Not required.
- Eye protection: Safety glasses
- Body protection: Protective work clothing.
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9 Physical and chemical properties:
- General Information
- Form: Pieces
- Colour: Silver grey
- Smell: Odourless
- Value/Range Unit Method
- Change in condition
- Melting point/Melting range: 1663 ° C
- Boiling point/Boiling range: 3402 ° C
- Sublimation temperature / start: Not determined
- Flash point: Not applicable
- Inflammability (solid, gaseous) Product is not inflammable.
Powder: flammable
- Ignition temperature: Not determined
- Decomposition temperature: Not determined
- Danger of explosion: Product is not explosive.
- Critical values for explosion:
- Lower: Not determined
- Upper: Not determined
- Steam pressure: Not determined
- Density at 20 ° C 9.84 g/cm³
- Solubility in / Miscibility with
- Water: Not determined
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10 Stability and reactivity
- Thermal decomposition / conditions to be avoided:
No decomposition if used and stored according to specifications.
- Materials to be avoided:
Oxidizing agents
Acids
Halogens
Water/moisture
Air
- Dangerous reactions:
Powder: contact with water liberates extremely flammable gases.
- Dangerous products of decomposition: Metal oxide
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11 Toxicological information
- Acute toxicity:
- Primary irritant effect:
- on the skin: No irritant effect.
- on the eye: No irritant effect.
- Sensitization: No sensitizing effect known.
- Additional toxicological information:
To the best of our knowledge the acute and chronic toxicity of this substance is not fully known.
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12 Ecological information:
- General notes:
Do not allow material to be released to the environment without proper governmental permits.
Water hazard class 1 (Self-assessment): slightly hazardous for water.
Do not allow undiluted product or large quantities of it to reach ground water, water bodies or sewage system.
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13 Disposal considerations
- Product:
- Recommendation
Consult state, local or national regulations for proper disposal.
Hand over to disposers of hazardous waste.
Must be specially treated under adherence to official regulations.
- Uncleaned packagings:
- Recommendation:
Disposal must be made according to official regulations.
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14 Transport information
- Land transport ADR/RID and GGVS/GGVE (cross-border/domestic)
- ADR/RID-GGVS/E Class: None
- Maritime transport IMDG/GGVSea:
- IMDG/GGVSea Class: None
- Air transport ICAO-TI and IATA-DGR:
- ICAO/IATA Class: None
- Transport/Additional information:
Not dangerous according to the above specifications.
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15 Regulatory information
- Designation according to EC guidelines:
Observe the normal safety regulations when handling chemicals
The product is not subject to identification regulations under EC Directives and the Ordinance on Hazardous Materials (GefStoffV).
- National regulations
- Information about limitation of use:
For use only by technically qualified individuals.
- Water hazard class:
Water hazard class 1 (Self-assessment): slightly hazardous for water.
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16 Other information:
Employers should use this information only as a supplement to other information gathered by them, and should make independent judgement of suitability of this information to ensure proper use and protect the health and safety of employees. This information is furnished without warranty, and any use of the product not in conformance with this Material Safety Data Plate, or in combination with any other product or process, is the responsibility of the user.
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Lutetium Foil Recent Research
- Separation of carrier-free hafnium and lutetium radionuclides produced in 16O activated terbium metal target.
Appl Radiat Isot. 2000 Jun;52(6):1399-405.
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