Photo-oxidative Cross-Dehydrogenative Coupling-Type Reaction of Thiophenes with ?-Position of Carbonyls Using a Catalytic Amount of Molecular Iodine.

Title Photo-oxidative Cross-Dehydrogenative Coupling-Type Reaction of Thiophenes with ?-Position of Carbonyls Using a Catalytic Amount of Molecular Iodine.
Authors Y. Sudo; E. Yamaguchi; A. Itoh
Journal Org Lett
DOI 10.1021/acs.orglett.7b00428
Abstract

A metal-free photo-oxidative intermolecular C-H/C-H coupling reaction of thiophenes is demonstrated with carbonyls using a catalytic amount of molecular iodine. In this system, molecular oxygen in the air acted as a terminal oxidant to regenerate molecular iodine. A mechanistic study was also performed.

Citation Y. Sudo; E. Yamaguchi; A. Itoh.Photo-oxidative Cross-Dehydrogenative Coupling-Type Reaction of Thiophenes with ?-Position of Carbonyls Using a Catalytic Amount of Molecular Iodine.. Org Lett. 2017;19(7):16101613. doi:10.1021/acs.orglett.7b00428

Related Elements

Iodine

See more Iodine products. Iodine (atomic symbol: I, atomic number: 53) is a Block P, Group 17, Period 5 element with an atomic radius of 126.90447. The number of electrons in each of Iodine's shells is 2, 8, 18, 18, 7 and its electron configuration is [Kr] 4d10 5s2 5p5. The iodine atom has a radius of 140 pm and a Van der Waals radius of 198 pm. In its elemental form, iodine has a lustrous metallic gray appearance as a solid and a violet appearance as a gas or liquid solution. Elemental IodineIodine forms compounds with many elements, but is less active than the other halogens. It dissolves readily in chloroform, carbon tetrachloride, or carbon disulfide. Iodine compounds are important in organic chemistry and very useful in the field of medicine. Iodine was discovered and first isolated by Bernard Courtois in 1811. The name Iodine is derived from the Greek word "iodes" meaning violet.

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