Iodotrimethylplatinum(IV) is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Iodide compounds are used in internal medicine. Treating an iodide with Platinum dioxide and sulfuric acid sublimes the iodine.American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia)and follows applicable ASTM testing standards.Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement.
Platinum is a Block D, Group 10, Period 6 element. The number of electrons in each of Platinum's shells is 2, 8, 18, 32, 17, 1 and its electronic configuration is [Xe] 4f14 5d9 6s1. In its elemental form platinum's CAS number is 7440-06-4. The platinum atom has a radius of 137.3.pm and it's Van derWaals radius is 172.pm. Platinum is not toxic. Platinum is a member of the platinum group of metals. It is highly corrosion resistant and has numerous catalytic applications. These include in petrochemical cracking catalysts, automotive catalytic converters and in the processes used for proton exchange membrane fuel cells. The metal does not oxidize in air at any temperature. The metal is extensively used in jewelry, electronic wire, and crucibles for corrosive and high temperature laboratory uses and in many advanced instruments. Platinum compounds have application in medicine. Platinum is available as metal and compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity); metals in the form of foil, sputtering target, and rod, and compounds as submicron and nanopowder. Platinum was first discovered by Julius Scaliger in 1735. The origin of the name comes from the Spanish word platina meaning silver. See Platinum research below.
Iodine is a Block P, Group 17, Period 5 element. The number of electrons in each of Iodine's shells is 2, 8, 18, 18, 7 and its electronic configuration is [Kr] 4d10 5s2 5p5. In its elemental form iodine's CAS number is 7553-56-2. The iodine atom has a radius of 133.1.pm and it's Van der Waals radius is 198.pm. Iodine in large amounts is poisonous but in small doses is only slightly toxic. Iodine forms compounds with many elements, but is less active than the other halogens, which displace it from iodides. Iodine exhibits some metallic-like properties. It dissolves readily in chloroform, carbon tetrachloride, or carbon disulfide to form purple solutions. It is only slightly soluble in water. Iodine compounds are important in organic chemistry and very useful in medicine. Iodides, and thyroxine which contains iodine, are used internally in medicine. Potassium iodide finds use in photography. The deep blue color with starch solution is characteristic of the free element.Iodine is available in compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity). See Iodine research below. Iodine it forms compounds with many elements, but is less active than the other halogens, which displace it from iodides. Iodine exhibits some metallic-like properties. It dissolves readily in chloroform, carbon tetrachloride, or carbon disulfide to form purple solutions. It is only slightly soluble in water. Iodine compounds are important in organic chemistry and very useful in medicine. Iodides, and thyroxine which contains iodine, are used internally in medicine. Potassium iodide finds use in photography. The deep blue color with starch solution is characteristic of the free element.Iodine is available in compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity). See Iodine research below.
PACKAGING SPECIFICATIONS FOR BULK & RESEARCH QUANTITIES
Typical bulk packaging includes palletized plastic 5 gallon/25 kg. pails, fiber and steel drums to 1 ton super sacks in full container (FCL) or truck load (T/L) quantities. Research and sample quantities and hygroscopic, oxidizing or other air sensitive materials may be packaged under argon or vacuum. Shipping documentation includes a Certificate of Analysis and Material Safety Data Sheet (MSDS). Solutions are packaged in polypropylene, plastic or glass jars up to palletized 440 gallon liquid totes.
S-1 Monotherapy for Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck After Progression on Platinum-based Chemotherapy.
Yokota T, Onozawa Y, Boku N, Hamauchi S, Tsushima T, Taniguchi H, Todaka A, Machida N, Yamazaki K, Fukutomi A, Yasui H.
Jpn J Clin Oncol. 2011 Oct 5. [Epub ahead of print]
PMID:
21980053
[PubMed - as supplied by publisher]
Gemcitabine and platinum pathway pharmacogenetics in asian breast cancer patients.
Wong AL, Yap HL, Yeo WL, Soong R, Ng SS, Wang LZ, Cordero MT, Yong WP, Goh BC, Lee SC.
Cancer Genomics Proteomics. 2011 Sep;8(5):255-9.
PMID:
21980041
[PubMed - in process]
Pt-rotaxanes as cytotoxic agents.
Wang X, Smithrud DB.
Bioorg Med Chem Lett. 2011 Sep 16. [Epub ahead of print]
PMID:
21978681
[PubMed - as supplied by publisher]
Effects of solvents on in vitro potencies of platinum compounds.
Yi YW, Bae I.
DNA Repair (Amst). 2011 Oct 4. [Epub ahead of print] No abstract available.
PMID:
21978437
[PubMed - as supplied by publisher]
DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies.
Rezaee M, Alizadeh E, Hunting D, Sanche L.
Bioinorg Chem Appl. 2012;2012:923914. Epub 2011 Oct 2.
PMID:
21977010
[PubMed - in process]
Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in partially platinum-sensitive ovarian cancer patients: results from a subset analysis of the CALYPSO phase III trial.
Gladieff L, Ferrero A, De Rauglaudre G, Brown C, Vasey P, Reinthaller A, Pujade-Lauraine E, Reed N, Lorusso D, Siena S, Helland H, Elit L, Mahner S.
Ann Oncol. 2011 Oct 5. [Epub ahead of print]
PMID:
21976386
[PubMed - as supplied by publisher]
Multiple hydrogen bondings in a platinum complex.
Tabei ES, Samouei H, Rashidi M.
Dalton Trans. 2011 Oct 6. [Epub ahead of print]
PMID:
21975945
[PubMed - as supplied by publisher]
Surgery for early-stage small cell lung cancer.
Schneider BJ, Saxena A, Downey RJ.
J Natl Compr Canc Netw. 2011 Oct;9(10):1132-9.
PMID:
21975913
[PubMed - in process]
Epidermal growth factor receptor blockers for the treatment of ovarian cancer.
Haldar K, Gaitskell K, Bryant A, Nicum S, Kehoe S, Morrison J.
Cochrane Database Syst Rev. 2011 Oct 5;10:CD007927.
PMID:
21975775
[PubMed - in process]
Adjuvant chemotherapy for endometrial cancer after hysterectomy.
Johnson N, Bryant A, Miles T, Hogberg T, Cornes P.
Cochrane Database Syst Rev. 2011 Oct 5;10:CD003175.
PMID:
21975736
[PubMed - in process]
Mechanism and release rates of surface confined cyclodextrin guests.
Mallon CT, Forster RJ, Keyes TE.
Analyst. 2011 Oct 6. [Epub ahead of print]
PMID:
21975325
[PubMed - as supplied by publisher]
Erlotinib Monotherapy for the Maintenance Treatment of Non-Small Cell Lung Cancer after Previous Platinum-Containing Chemotherapy: A NICE Single Technology Appraisal.
Dickson R, Bagust A, Boland A, Blundell M, Davis H, Dundar Y, Hockenhull J, Martin Saborido C, Oyee J, Ramani VS.
Pharmacoeconomics. 2011 Oct 3. [Epub ahead of print]
PMID:
21967156
[PubMed - as supplied by publisher]
Low temperature crystallization of transparent, highly ordered nanoporous SnO(2) thin films: application to room-temperature hydrogen sensing.
Shao S, Qiu X, He D, Koehn R, Guan N, Lu X, Bao N, Grimes CA.
Nanoscale. 2011 Oct 5;3(10):4283-9. Epub 2011 Aug 30.
PMID:
21879121
[PubMed - in process]
Design, synthesis, characterization, luminescence and non-linear optical (NLO) properties of multinuclear platinum(ii) alkynyl complexes.
Chan CK, Tao CH, Li KF, Wong KM, Zhu N, Cheah KW, Yam VW.
Dalton Trans. 2011 Oct 28;40(40):10670-85. Epub 2011 Aug 19.
PMID:
21858294
[PubMed - in process]
Platinum porphyrins as ionophores in polymeric membrane electrodes.
Lvova L, Verrelli G, Stefanelli M, Nardis S, Di Natale C, Amico AD, Makarychev-Mikhailov S, Paolesse R.
Analyst. 2011 Oct 4. [Epub ahead of print]
PMID:
21971176
[PubMed - as supplied by publisher]
Acquired platinum resistance enhances tumour angiogenesis through angiotensin II type 1 receptor in bladder cancer.
Tanaka N, Miyajima A, Kosaka T, Miyazaki Y, Shirotake S, Shirakawa H, Kikuchi E, Oya M.
Br J Cancer. 2011 Oct 4. doi: 10.1038/bjc.2011.399. [Epub ahead of print]
PMID:
21970881
[PubMed - as supplied by publisher]
Preclinical emergence of vandetanib as a potent antitumour agent in mesothelioma: molecular mechanisms underlying its synergistic interaction with pemetrexed and carboplatin.
Giovannetti E, Zucali PA, Assaraf YG, Leon LG, Smid K, Alecci C, Giancola F, Destro A, Gianoncelli L, Lorenzi E, Roncalli M, Santoro A, Peters GJ.
Br J Cancer. 2011 Oct 4. doi: 10.1038/bjc.2011.400. [Epub ahead of print]
PMID:
21970874
[PubMed - as supplied by publisher]
An indirect comparison of the efficacy of bevacizumab plus carboplatin and paclitaxel versus pemetrexed with cisplatin in patients with advanced or recurrent non-squamous adenocarcinoma non-small cell lung cancer.
Nuijten MJ, Aultman R, Carpeño JD, Vergnenègre A, Chouaid C, Walzer S, Siebert U.
Curr Med Res Opin. 2011 Oct 4. [Epub ahead of print]
PMID:
21970659
[PubMed - as supplied by publisher]
Hypersensitivity reactions to anticancer agents: data mining of the public version of the FDA Adverse Event Reporting System, AERS.
Kadoyama K, Kuwahara A, Yamamori M, Brown J, Sakaeda T, Okuno Y.
J Exp Clin Cancer Res. 2011 Oct 5;30(1):93. [Epub ahead of print]
PMID:
21970649
[PubMed - as supplied by publisher]
Reactions of metallodrugs with proteins: selective binding of phosphane-based platinum(ii) dichlorides to horse heart cytochrome c probed by ESI MS coupled to enzymatic cleavage.
Mügge C, Micheucci E, Boscaro F, Gabbiani C, Messori L, Weigand W.
Metallomics. 2011 Oct 4;3(10):987-90. Epub 2011 Sep 22.
PMID:
21947338
[PubMed - in process]
Recent Research & Development for Iodine
Approach to management of the patient with primary or secondary intrathoracic goiter.
Hegedüs L, Bonnema SJ.
J Clin Endocrinol Metab. 2010 Dec;95(12):5155-62.PMID: 21131536 [PubMed - in process]Related citations
SYSTEMATIC INVESTIGATION ON THE SYNTHESIS OF ANDROSTANE-BASED 3-; 11- AND 17-CARBOXAMIDES VIA PALLADIUM-CATALYZED AMINOCARBONYLATION.
Acs P, Takács A, Kiss M, Pálinkás N, Mahó S, Kollár L.
Steroids. 2010 Dec 2. [Epub ahead of print]PMID: 21130794 [PubMed - as supplied by publisher]Related citations
Intraoperative patient skin prep agents: is there a difference?
Zinn J, Jenkins JB, Swofford V, Harrelson B, McCarter S.
AORN J. 2010 Dec;92(6):662-74.PMID: 21130204 [PubMed - in process]Related citations
Non-malignant Thyroid Diseases after a Wide Range of Radiation Exposures.
Ron E, Brenner A.
Radiat Res. 2010 Dec;174(6):877-88. Epub 2010 Sep 7.PMID: 21128812 [PubMed - in process]Related citations
Prevalence of Hyperthyroidism after Exposure during Childhood or Adolescence to Radioiodines from the Chornobyl Nuclear Accident: Dose-Response Results from the Ukrainian-American Cohort Study.
Hatch M, Furukawa K, Brenner A, Olinjyk V, Ron E, Zablotska L, Terekhova G, McConnell R, Markov V, Shpak V, Ostroumova E, Bouville A, Tronko M.
Radiat Res. 2010 Dec;174(6):763-72. Epub 2010 Oct 7.PMID: 21128800 [PubMed - in process]Related citations
Comparative Biodistribution of PAMAM Dendrimers and HPMA Copolymers in Ovarian-Tumor-Bearing Mice.
Sadekar S, Ray A, Janàt-Amsbury M, Peterson CM, Ghandehari H.
Biomacromolecules. 2010 Dec 3. [Epub ahead of print]PMID: 21128624 [PubMed - as supplied by publisher]Related citations
Gold nanoparticles functionalized with gadolinium-diethylenetriamine pentaacetic acid-cysteine conjugate.
Shan L.
Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2010.
2010 Sep 24 [updated 2010 Nov 17].PMID: 21089255 [PubMed]Books & DocumentsFree textRelated citations
Gold nanoparticles coated with dithiolated diethylenetriamine pentaacetic acid-gadolinium chelate.
Shan L.
Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2010.
2010 Sep 24 [updated 2010 Nov 17].PMID: 21089230 [PubMed]Books & DocumentsFree textRelated citations
Usefulness of impairment of cardiac adrenergic nerve function to predict outcome in patients with cardiac syndrome x.
Di Monaco A, Lanza GA, Bruno I, Careri G, Pinnacchio G, Tarzia P, Battipaglia I, Giordano A, Crea F.
Am J Cardiol. 2010 Dec 15;106(12):1813-8. Epub 2010 Nov 2.PMID: 21126626 [PubMed - in process]Related citations
Thyroid function and pregnancy: Before, during and beyond.
Kennedy RL, Malabu UH, Jarrod G, Nigam P, Kannan K, Rane A.
J Obstet Gynaecol. 2010;30(8):774-83.PMID: 21126112 [PubMed - in process]Related citations
A Multidimensional Study of the Reaction CH(2)I+O(2): Products and Atmospheric Implications.
Gravestock TJ, Blitz MA, Bloss WJ, Heard DE.
Chemphyschem. 2010 Dec 1. [Epub ahead of print]PMID: 21125552 [PubMed - as supplied by publisher]Related citations
Preparation of functionalized organoaluminiums by direct insertion of aluminium to unsaturated halides.
Blümke T, Chen YH, Peng Z, Knochel P.
Nat Chem. 2010 Apr;2(4):313-8. Epub 2010 Mar 24.PMID: 21124514 [PubMed - in process]Related citations
Converting homogeneous to heterogeneous in electrophilic catalysis using monodisperse metal nanoparticles.
Witham CA, Huang W, Tsung CK, Kuhn JN, Somorjai GA, Toste FD.
Nat Chem. 2010 Jan;2(1):36-41. Epub 2009 Nov 29.PMID: 21124378 [PubMed - in process]Related citations
Has the time come for plastic surgeons to move from povidone-iodine to chlorhexidine?
Hassid VJ.
Plast Reconstr Surg. 2010 Dec;126(6):327e-8e. No abstract available. PMID: 21124119 [PubMed - in process]Related citations
Repeated injection of high doses of hemoglobin encapsulated liposomes (hemoglobin-vesicles) induces accelerated blood clearance in a hemorrhagic shock rat model.
Taguchi K, Iwao Y, Watanabe H, Kadowaki D, Sakai H, Kobayashi K, Horinouchi H, Maruyama T, Otagiri M.
Drug Metab Dispos. 2010 Dec 1. [Epub ahead of print]PMID: 21123166 [PubMed - as supplied by publisher]Related citations
Stereocontrolled Total Syntheses of Isodomoic Acids G and H via a Unified Strategy.
Denmark SE, Liu JH, Muhuhi JM.
J Org Chem. 2010 Dec 1. [Epub ahead of print]PMID: 21121685 [PubMed - as supplied by publisher]Related citations
Diabetes aggravates nanoparticles induced breakdown of the blood-brain barrier permeability, brain edema formation, alterations in cerebral blood flow and neuronal injury. An experimental study using physiological and morphological investigations in the rat.
Sharma HS, Patnaik R, Sharma A.
J Nanosci Nanotechnol. 2010 Dec;10(12):7931-45.PMID: 21121280 [PubMed - in process]Related citations
Gelatin as a bioorganic reductant, ligand and support for palladium nanoparticles. Application as a catalyst for ligand- and amine-free Sonogashira-Hagihara reaction.
Firouzabadi H, Iranpoor N, Ghaderi A.
Org Biomol Chem. 2010 Nov 30. [Epub ahead of print]PMID: 21120230 [PubMed - as supplied by publisher]Related citations
Management of cystic lymphangioma in the head and neck region: endoscopic cautery and postoperative intratumoral negative pressure.
Shen W, Weiping S, Cui J, Chen J, Zou J.
J Craniofac Surg. 2010 Nov;21(6):1884-6.PMID: 21119446 [PubMed - in process]Related citations
Do histological, immunohistochemical and metabolic (radioiodine and fluorodeoxyglucose uptake) patterns of metastatic thyroid cancer correlate with patient outcome?
Deandreis D, Al Ghuzlan A, Leboulleux S, Lacroix L, Garsi JP, Talbot M, Lumbroso J, Baudin E, Caillou B, Bidart JM, Schlumberger M.
Endocr Relat Cancer. 2010 Nov 30. [Epub ahead of print]PMID: 21118976 [PubMed - as supplied by publisher]Related citations
Platinum is a Block D, Group 10, Period 6 element. The number of electrons in each of Platinum's shells is 2, 8, 18, 32, 17, 1 and its electronic configuration is [Xe] 4f14 5d9 6s1. In its elemental form platinum's CAS number is 7440-06-4. The platinum atom has a radius of 137.3.pm and it's Van derWaals radius is 172.pm. Platinum is not toxic. Platinum is a member of the platinum group of metals. It is highly corrosion resistant and has numerous catalytic applications. These include in petrochemical cracking catalysts, automotive catalytic converters and in the processes used for proton exchange membrane 
not oxidize in air at any
temperature. The metal is extensively used in jewelry, electronic wire, and crucibles for corrosive and high temperature laboratory uses and in many advanced instruments. Platinum compounds have application in medicine. Platinum is available as metal and compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity); metals in the form of foil, sputtering target, and rod, and compounds as submicron and nanopowder. Platinum was first discovered by Julius Scaliger in 1735. The origin of the name comes from the Spanish word platina meaning silver. See Platinum research below.
Iodine is a Block P, Group 17, Period 5 element. The number of electrons in each of Iodine's shells is 2, 8, 18, 18, 7 and its electronic configuration is [Kr] 4d10 5s2 5p5. In its elemental form iodine's CAS number is 7553-56-2. The iodine atom has a radius of 133.1.pm and it's Van der Waals radius is 198.pm. Iodine in large amounts is poisonous but in small doses is only slightly toxic. Iodine forms compounds with many elements, but is less active than the other halogens, which displace it from iodides. Iodine exhibits some metallic-like properties. It dissolves readily in chloroform, carbon tetrachloride, or carbon disulfide to form purple solutions. It is only slightly soluble in water. Iodine compounds are important in organic chemistry and very useful in medicine. Iodides, and thyroxine which contains iodine, are used internally 
in medicine. Potassium iodide finds use in photography. The deep blue color with starch solution is characteristic of the free element.Iodine is available in compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity). See Iodine research below. Iodine it forms compounds with many elements, but is less active than the other halogens, which displace it from iodides. Iodine exhibits some metallic-like properties. It dissolves readily in chloroform, carbon tetrachloride, or carbon disulfide to form purple solutions. It is only slightly soluble in water. Iodine compounds are important in organic chemistry and very useful in medicine. Iodides, and thyroxine which contains iodine, are used internally in medicine. Potassium iodide finds use in photography. The deep blue color with starch solution is characteristic of the free element.Iodine is available in compounds with purities from 99% to 99.999% (ACS grade to ultra-high purity). See Iodine research below. 
