Liquid Exfoliation of Colloidal Rhenium Disulfide Nanosheets as a Multifunctional Theranostic Agent for In Vivo Photoacoustic/CT Imaging and Photothermal Therapy.

Title Liquid Exfoliation of Colloidal Rhenium Disulfide Nanosheets as a Multifunctional Theranostic Agent for In Vivo Photoacoustic/CT Imaging and Photothermal Therapy.
Authors Z.H. Miao; L.X. Lv; K. Li; P.Y. Liu; Z. Li; H. Yang; Q. Zhao; M. Chang; L. Zhen; C.Y. Xu
Journal Small
DOI 10.1002/smll.201703789
Abstract

Near-infrared light-mediated theranostic agents with superior tissue penetration and minimal invasion have captivated researchers in cancer research in the past decade. Herein, a probe sonication-assisted liquid exfoliation approach for scalable and continual synthesis of colloidal rhenium disulfide nanosheets, which is further explored as theranostic agents for cancer diagnosis and therapy, is reported. Due to high-Z element of Re (Z = 75) and significant photoacoustic effect, the obtained PVP-capped ReS nanosheets are evaluated as bimodality contrast agents for computed tomography and photoacoustic imaging. In addition, utilizing the strong near-infrared absorption and ultrahigh photothermal conversion efficiency (79.2%), ReS nanosheets could also serve as therapeutic agents for photothermal ablation of tumors with a tumor elimination rate up to 100%. Importantly, ReS nanosheets show no obvious toxicity based on the cytotoxicity assay, serum biochemistry, and histological analysis. This work highlights the potentials of ReS nanosheets as a single-component theranostic nanoplatform for bioimaging and antitumor therapy.

Citation Z.H. Miao; L.X. Lv; K. Li; P.Y. Liu; Z. Li; H. Yang; Q. Zhao; M. Chang; L. Zhen; C.Y. Xu.Liquid Exfoliation of Colloidal Rhenium Disulfide Nanosheets as a Multifunctional Theranostic Agent for In Vivo Photoacoustic/CT Imaging and Photothermal Therapy.. Small. 2018;14(14):e1703789. doi:10.1002/smll.201703789

Related Elements

Rhenium

See more Rhenium products. Rhenium (atomic symbol: Re, atomic number: 75) is a Block D, Group 7, Period 6 element with an atomic weight of 186.207. The number of electrons in each of rhenium's shells is 2, 8, 18, 32, 13, 2 and its electron configuration is [Xe] 4f14 5d5 6s2. Rhenium Bohr ModelThe rhenium atom has a radius of 137 pm and a Van der Waals radius of 217 pm. Rhenium was discovered and first isolated by Masataka Ogawa in 1908. In its elemental form, rhenium has a silvery-white appearance. Rhenium is the fourth densest element exceeded only by platinum, iridium, and osmium. Rhenium's high melting point is exceeded only by those of tungsten and carbon.Elemental Rhenium Rhenium is found in small amounts in gadolinite and molybdenite. It is usually extracted from the flue dusts of molybdenum smelters. The name Rhenium originates from the Latin word 'Rhenus' meaning "Rhine" after the place of discovery.

Sulfur

See more Sulfur products. Sulfur (or Sulphur) (atomic symbol: S, atomic number: 16) is a Block P, Group 16, Period 3 element with an atomic radius of 32.066. Sulfur Bohr ModelThe number of electrons in each of Sulfur's shells is 2, 8, 6 and its electron configuration is [Ne] 3s2 3p4. In its elemental form, sulfur has a light yellow appearance. The sulfur atom has a covalent radius of 105 pm and a Van der Waals radius of 180 pm. In nature, sulfur can be found in hot springs, meteorites, volcanoes, and as galena, gypsum, and epsom salts. Sulfur has been known since ancient times but was not accepted as an element until 1777, when Antoine Lavoisier helped to convince the scientific community that it was an element and not a compound.

Related Forms & Applications