PLLA microcapsules combined with silver nanoparticles and chlorhexidine acetate showing improved antibacterial effect.

Title PLLA microcapsules combined with silver nanoparticles and chlorhexidine acetate showing improved antibacterial effect.
Authors Y. Zhou; K. Hu; Z. Guo; K. Fang; X. Wang; F. Yang; N. Gu
Journal Mater Sci Eng C Mater Biol Appl
DOI 10.1016/j.msec.2017.04.100
Abstract

In this study, composite antibacterial microcapsules combining of two antibacterial agents: chlorhexidine acetate and silver nanoparticle were prepared. The chlorhexidine acetate was encapsulated inside of the microcapsules and nano-sized silver particles were modified on the surface of microcapsules by electrostatic adsorption methods. Results show that this method decreases the silver usage dramatically, and promises a sustained antibacterial effect >30days. These microcapsules can also be modified on the surface of polymer films easily, which demonstrated the potential in functionalizing the implanted materials with antibacterial property.

Citation Y. Zhou; K. Hu; Z. Guo; K. Fang; X. Wang; F. Yang; N. Gu.PLLA microcapsules combined with silver nanoparticles and chlorhexidine acetate showing improved antibacterial effect.. Mater Sci Eng C Mater Biol Appl. 2017;78:349353. doi:10.1016/j.msec.2017.04.100

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Silver

See more Silver products. Silver (atomic symbol: Ag, atomic number: 47) is a Block D, Group 11, Period 5 element with an atomic weight of 107.8682. Silver Bohr ModelThe number of electrons in each of Silver's shells is 2, 8, 18, 18, 1 and its electron configuration is [Kr]4d10 5s1. The silver atom has a radius of 144 pm and a Van der Waals radius of 203 pm. Silver was first discovered by Early Man prior to 5000 BC. In its elemental form, silver has a brilliant white metallic luster. Elemental SilverIt is a little harder than gold and is very ductile and malleable, being exceeded only by gold and perhaps palladium. Pure silver has the highest electrical and thermal conductivity of all metals and possesses the lowest contact resistance. It is stable in pure air and water, but tarnishes when exposed to ozone, hydrogen sulfide, or air containing sulfur. It is found in copper, copper-nickel, lead, and lead-zinc ores, among others. Silver was named after the Anglo-Saxon word "seolfor" or "siolfur," meaning 'silver'.

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