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CAS #:

Linear Formula:


MDL Number:


EC No.:



(2N) 99% Carboplatin
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(3N) 99.9% Carboplatin
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(4N) 99.99% Carboplatin
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(5N) 99.999% Carboplatin
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Carboplatin Properties (Theoretical)

Compound Formula C6H12N2O4Pt
Molecular Weight 371.26
Appearance White crystals or powder
Melting Point N/A
Boiling Point N/A
Density N/A
Exact Mass 371.044498
Monoisotopic Mass 371.044498

Carboplatin Health & Safety Information

Signal Word Danger
Hazard Statements H302 + H312 + H332-H317-H334-H340-H360
Hazard Codes T
Risk Codes 46-61-20/21/22-42/43
Safety Statements 53-22-26-36/37/39-45
RTECS Number TP2300000
Transport Information N/A
WGK Germany 3

View and Print SDS


Date Accessed: 03/18/2018
Date Revised: 05/15/2015


Product Name: Carboplatin

Product Number: All applicable American Elements product codes, e.g. PT-OMX-02 , PT-OMX-03 , PT-OMX-04 , PT-OMX-05

CAS #: 41575-94-4

Relevant identified uses of the substance: Scientific research and development

Supplier details:
American Elements
10884 Weyburn Ave.
Los Angeles, CA 90024
Tel: +1 310-208-0551
Fax: +1 310-208-0351

Emergency telephone number:
Domestic, North America: +1 800-424-9300
International: +1 703-527-3887


2.1 Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 4), H302
Acute toxicity, Inhalation (Category 4), H332
Acute toxicity, Dermal (Category 4), H312
Respiratory sensitisation (Category 1), H334
Skin sensitisation (Category 1), H317
Germ cell mutagenicity (Category 1B), H340
Reproductive toxicity (Category 1B), H360

2.2 GHS Label elements, including precautionary statements

Health Hazard - GHS08Exclamation Mark - GHS07

Signal word Danger
Hazard statement(s)
H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled
H317 May cause an allergic skin reaction.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H340 May cause genetic defects.
H360 May damage fertility or the unborn child.
Precautionary statement(s)
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and
P261 Avoid breathing dust/ fume/ gas/ mist/ Vapors/ spray.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
P285 In case of inadequate ventilation wear respiratory protection.
P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you
feel unwell. Rinse mouth.
P302 + P352 + P312 IF ON SKIN: Wash with plenty of soap and water. Call a POISON
CENTER or doctor/ physician if you feel unwell.
P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for
breathing. Call a POISON CENTER or doctor/ physician if you feel
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P333 + P313 If skin irritation or rash occurs: Get medical advice/ attention.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal plant.
2.3 Hazards not otherwise classified (HNOC) or not covered by GHS - none


3.1 Substances
Synonyms : cis-Diammine(1,1-cyclobutanedicarboxylato) platinum
Formula : C6H12N2O4Pt
Molecular weight : 371.25 g/mol
CAS-No. : 41575-94-4
EC-No. : 255-446-0
Hazardous components
Component Classification Concentration
Acute Tox. 4; Resp. Sens. 1;
Skin Sens. 1; Muta. 1B; Repr.
1B; H302 + H312 + H332,
H317, H334, H340, H360
<= 100 %


4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.Move out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available


5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx)
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available


6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing Vapors, mist or gas. Ensure adequate
ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for
6.4 Reference to other sections
For disposal see section 13.


7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place.
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated


8.1 Control parameters
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Hazardous components without workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without
touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after
use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method:
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the
supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an
industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It
should not be construed as offering an approval for any specific use scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected according to
the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type
N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the
sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.


9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
b) Odor No data available
c) Odor Threshold No data available
d) pH No data available
e) Melting point/freezing
No data available
f) Initial boiling point and
boiling range
No data available
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
j) Upper/lower flammability or explosive limits
No data available
k) Vapor pressure No data available
l) Vapor density No data available
m) Relative density No data available
n) Water solubility No data available
o) Partition coefficient: noctanol/water
No data available
p) Auto-ignition
No data available
q) Decomposition
No data available
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available


10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
Other decomposition products - No data available
In the event of fire: see section 5


11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - 343 mg/kg
No data available
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitisation
No data available
Germ cell mutagenicity
In vivo tests showed mutagenic effects
No data available
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a
known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a
carcinogen or potential carcinogen by OSHA.
Reproductive toxicity
Presumed human reproductive toxicant
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
RTECS: TP2300000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly
investigated., Vomiting, prolonged or repeated exposure can cause:, Liver injury may occur., Kidney injury may occur.
Stomach - Irregularities - Based on Human Evidence
Stomach - Irregularities - Based on Human Evidence


12.1 Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Other adverse effects
No data available


13.1 Waste treatment methods
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste
disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a
chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.


Not dangerous goods
Not dangerous goods
Not dangerous goods


SARA 302 Components
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components
This material does not contain any chemical components with known CAS numbers that exceed the threshold (De
Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards
Acute Health Hazard, Chronic Health Hazard
Massachusetts Right To Know Components
No components are subject to the Massachusetts Right to Know Act.
Pennsylvania Right To Know Components
Revision Date
New Jersey Right To Know Components
Revision Date
California Prop. 65 Components
WARNING: This product contains a chemical known to the
State of California to cause birth defects or other reproductive


Safety Data Sheet according to Regulation (EC) No. 1907/2006 (REACH). The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. American Elements shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. COPYRIGHT 1997-2018 AMERICAN ELEMENTS. LICENSED GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY.

About Carboplatin

Carboplatin (formal name: (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato(2-)-κO,κO'']-platinum) is a organometallic compound and one of several platinum-based antineoplastic agents used in certain types of chemotherapy for the treatment of cancer. These compounds, also known as platins, include Cisplatin, Oxaliplatin, Nedaplatin, and Satraplatin. Please note that this material is for research purposes only and not intended for human use. American Elements supplies all organometallic products in most volumes including bulk quantities and also can produce materials to customer specifications. Please request a quote above for more information on pricing and lead time.

Carboplatin Synonyms

Diammine-(1,1-cyclobutanedicarboxylato)platinum(II), 1,1-Cyclobutanedicarboxylatodiammineplatinum(II), CBDCA, cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II), cis-diammine(cyclobutane-1,1-dicarboxylate-O,O')platinum(II), carboplatinum, paraplatin, carbo platin

Chemical Identifiers

Linear Formula C6H12N2O4Pt
MDL Number MFCD00070464
EC No. 255-446-0
Beilstein Registry No. N/A
Pubchem CID 10339178
IUPAC Name azane; cyclobutane-1,1-dicarboxylate; platinum(2+)
SMILES C1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+2]
InchI Identifier InChI=1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2/p-2

Packaging Specifications

Typical bulk packaging includes palletized plastic 5 gallon/25 kg. pails, fiber and steel drums to 1 ton super sacks in full container (FCL) or truck load (T/L) quantities. Research and sample quantities and hygroscopic, oxidizing or other air sensitive materials may be packaged under argon or vacuum. Shipping documentation includes a Certificate of Analysis and Safety Data Sheet (SDS). Solutions are packaged in polypropylene, plastic or glass jars up to palletized 440 gallon liquid totes, and 36,000 lb. tanker trucks.

Related Elements

See more Nitrogen products. Nitrogen is a Block P, Group 15, Period 2 element. Its electron configuration is [He]2s22p3. In its elemental form, nitrogen's CAS number is 7727-37-9. Nitrogen is an odorless, tasteless, colorless and mostly inert gas. It is the seventh most abundant element in the universe and it constitutes 78.09% (by volume) of Earth's atmosphere. Nitrogen was discovered by Daniel Rutherford in 1772.

See more Platinum products. Platinum (atomic symbol: Pt, atomic number: 78) is a Block D, Group 10, Period 6 element with an atomic weight of 195.084. The number of electrons in each of platinum's shells is [2, 8, 18, 32, 17, 1] and its electron configuration is [Xe] 4f14 5d9 6s1. The platinum atom has a radius of 139 pm and a Van der Waals radius of 175 pm. Platinum Bohr ModelElemental PlatinumPlatinum was discovered and first isolated by Antonio de Ulloa in 1735. It is one of the rarest elements in the earth's crust, occurring at a concentration of only 0.005 ppm. Platinum is found uncombined as a free element and alloyed with iridium as platiniridium. In its elemental form, platinum has a grayish white appearance. It is highly resistant to corrosion: the metal does not oxidize in air at any temperature. It is generally non-reactive, even at high temperatures. The origin of the name "platinum" comes from the Spanish word platina, meaning silver.


March 18, 2018
Los Angeles, CA
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