Au-Ag alloy/porous-SiO core/shell nanoparticle-based surface-enhanced Raman scattering nanoprobe for ratiometric imaging analysis of nitric oxide in living cells.

Author(s) Li, L.; Si, Y.; He, B.; Li, J.
Journal Talanta
Date Published 2019 Dec 01

2 In this paper, we developed a novel surface-enhanced Raman scattering (SERS) nanoprobe via the assembly of 3,4-diaminobenzene-thiol on the surface of porous SiO-coated Au-Ag alloy nanoparticles and successfully applied this for ratiometric imaging analysis of NO in living cells. This nanoprobe exhibits excellent biocompatibility and chemical stability, superior SERS enhancement capacity, and good signal reproducibility. To the best of our knowledge, this is the first report of a porous SiO-coated Au-Ag alloy nanoparticle and ratiometric-based SERS nanosensor to be used for the detection of NO in living cells.

DOI 10.1016/j.talanta.2019.120116
ISSN 1873-3573
Citation Talanta. 2019;205:120116.

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