HPLC-ESI-MS method for C fullerene mitochondrial content quantification.

Author(s) Grebinyk, A.; Grebinyk, S.; Prylutska, S.; Ritter, U.; Matyshevska, O.; Dandekar, T.; Frohme, M.
Journal Data Brief
Date Published 2018 Aug
Abstract

The presented dataset describes the quantification of carbon nanoparticle C fullerene accumulated in mitochondria of human leukemic cells treated with nanostructure. Firstly, the high performance liquid chromatography-electro spray ionization-mass spectrometry (HPLC-ESI-MS) method was developed for quantitative analysis of pristine C fullerene. Then, human leukemic cells were incubated with C fullerene, homogenized and subjected to the differential centrifugation to retrieve mitochondrial fraction. The C fullerene content was quantified by HPLC-ESI-MS in extracts of cellular fractions. This data article refers to the research article "C Fullerene Accumulation in Human Leukemic Cells and Perspectives of LED-mediated Photodynamic Therapy" by Grebinyk et al. [1].

DOI 10.1016/j.dib.2018.06.089
ISSN 2352-3409
Citation Grebinyk A, Grebinyk, ii S, Prylutska S, Ritter U, Matyshevska O, Dandekar T, et al. HPLC-ESI-MS method for C fullerene mitochondrial content quantification. Data Brief. 2018;19:2047-2052.

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