Insertion of germanium atoms in high-nuclearity rhodium carbonyl compounds: synthesis, characterization and preliminary biological activity of the heterometallic [RhGe(CO)], [RhGe(CO)] and [RhGe(CO)] clusters.

Author(s) Boccalini, A.; Dyson, P.J.; Femoni, C.; Iapalucci, M.C.; Ruggieri, S.; Zacchini, S.
Journal Dalton Trans
Date Published 2018 Nov 13
Abstract

The reaction of the [Rh7(CO)16]3- cluster anion with Ge2+ salts, in different stoichiometric ratios and under different atmospheres, leads to the formation of new heterometallic Rh-Ge clusters, representing the first known examples of Rh carbonyl compounds containing interstitial germanium atoms. More specifically, under N2 the reaction progressively affords the new [Rh13Ge(CO)25]3- and [Rh14Ge2(CO)30]2- clusters in good yields, with the Ge atoms located in cubic and square-anti-prismatic cavities, respectively. However, under a CO atmosphere, the [Rh13Ge(CO)25]3- derivative undergoes a significant structural and chemical rearrangement giving the new compound, [Rh12Ge(CO)27]4-, where Ge is hosted in an icosahedral metal cage. All species have been characterized by IR spectroscopy and ESI mass spectrometry, and their structures have been elucidated by single-crystal X-ray diffraction. Additionally, preliminary biological tests on the [Rh13Ge(CO)25]3- and [Rh14Ge2(CO)30]2- clusters show that they are cytotoxic to various cell lines.

DOI 10.1039/c8dt02466a
ISSN 1477-9234
Citation Boccalini A, Dyson PJ, Femoni C, Iapalucci MC, Ruggieri S, Zacchini S. Insertion of germanium atoms in high-nuclearity rhodium carbonyl compounds: synthesis, characterization and preliminary biological activity of the heterometallic [RhGe(CO)], [RhGe(CO)] and [RhGe(CO)] clusters. Dalton Trans. 2018;47(44):15737-15744.

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